Search Results - drug+screening

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Micro-Droplet Generator for Time-Resolved Solution Scattering
Invention Description Accurate liquid sample delivery is important for applications ranging from biomedical diagnostics to advanced X-ray and electron spectroscopy, scattering, and diffraction. Producing droplets with precise volume, timing, and placement offers significant advantages, including higher efficiency, lower sample consumption, and better...
Published: 3/31/2026   |   Updated: 3/31/2026   |   Inventor(s): Adil Ansari, Richard Kirian, Reza Nazari
Keywords(s): Additive Manufacturing, Drug Delivery, Drug Screening
Category(s): Manufacturing/Construction/Mechanical, Pharmaceuticals, Physical Science, Imaging, Bioanalytical Assays, Chemistries & Devices
A Rat Model of IgA Nephropathy
NU 2019-196 INVENTORS Jing Jin* Xinfang Xie SHORT DESCRIPTION A novel rat model of IgA nephropathy (IgAN, also known as Berger's disease), enabling reproducible kidney mesangial deposits characteristic of the human disease for therapeutic and diagnostic evaluation. BACKGROUND IgAN, the most common glomerulonephritis worldwide, results...
Published: 4/13/2026   |   Updated: 2/26/2026   |   Inventor(s):  
Keywords(s): Animal Model, Antibody, Drug screening, Immunology, Inflammation, Renal Disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
TauSeeK: Disease Specific Tau Protein Fibrils & Seeding Proteins
NU 2024-154 INVENTORS Songi Han* Austin Dubose Michael Vigers Andrew Longhini Vishnu Vijayan Kenneth Kosik Samuel Lobo Peter C. Ryffel Lokeswara Rao Potnuru Karen Tsay Chung-Ta Han SHORT DESCRIPTION Compositions, kits, and methods for generating synthetic miniature tau peptides and fibrils, and synthetic full-length pathogenic tau...
Published: 3/23/2026   |   Updated: 10/30/2025   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Drug discovery, Drug screening, HD - Huntington's Disease, Neurodegenerative disease, Neurology, PD - Parkinson's Disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening
NU 2010-131 INVENTORS Vadim Backman* Dhwanil Damania Dhananjay Kunte Hariharan Subramanian Hemant Roy Mart De La Cruz SHORT DESCRIPTION This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer. BACKGROUND Colorectal...
Published: 12/9/2025   |   Updated: 10/10/2025   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Colon cancer, Diagnostics, Drug screening, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Compounds to Modulate Retinoid X Receptors
The human retinoid X receptors (RXRs) function as transcriptional regulators, often in partnership with members of a larger nuclear receptor family of transcription factors. RXR agonists have been shown to modulate RXR transcription and activate or repress various biological pathways and effect therapeutic results for various conditions. There are a...
Published: 2/26/2026   |   Updated: 8/27/2025   |   Inventor(s): Carl Wagner, Peter Jurutka, Pamela Marshall, Arjan Van Der Vaart
Keywords(s): Bio-Technology, Drug Screening
Category(s): Life Science (All LS Techs), Cancer Therapeutics, Pharmaceuticals, Neurodegenerative Disease Technologies, Non-Cancer Therapeutics
Multi-Particle System for Capture and Detection of Cellular and Molecular Analytes (Case No. 2025-267)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel multi-particle system that selectively confines cells and molecular reactions within cavities formed by interacting particles. Background: Screening and selecting cells with specific, beneficial traits has become a vital process in using cell-derived products...
Published: 10/20/2025   |   Updated: 7/29/2025   |   Inventor(s): Dino Di Carlo, Alyssa Arnheim, Michael Mellody, Yuta Nakagawa, Lily Shang
Keywords(s): Assay, B Cell, barcode, Bioassay, biological assays, Biomarker, biomarkers, Biomaterial, capping particles, CAR-T cell platform, CAR-T cell therapy, cavities, cavity-containing particles, Cell and tissue culture, cell encapsulation, cell engineering, cell imaging, cell mapping, cell sorting, cell type identification, cell-based therapy, centrifugation, confinement, Diagnostic Platform Technologies (E.G. Microfluidics), Digital Microfluidics, Drug, Drug Delivery, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, Immunoassay, Immunoassay Sense (Molecular Biology), Microfluidics, Microfluidics And Mem's, Microfluidics Nanosphere, microparticles, moieties, Nanoparticle, single cell analysis, single cell analysis and testing, Single cell data, single-cell resolution, single-cell trapping
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices, Platforms
Synapticflow Universal Scientific MPC/API Gateway (Case No. 2025-265)
Summary: UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed an advanced API gateway that leverages AI to autonomously process data requests with exceptional speed, reliability, and efficiency. Background: Application Programming Interface (API) infrastructures are universally employed to enable...
Published: 12/23/2025   |   Updated: 7/16/2025   |   Inventor(s): Lulan Wang
Keywords(s): AI, AI algorithms, Artifical Intelligence (Machine Learning, Data Mining), Coronavirus, Data Acquisition, Data Analytics, data security, Data Structure, Drug Discovery, drug screening, high speed, Medical diagnostics, Software, Software & Algorithms, Software Development Tools
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Bioinformatics, Software & Algorithms > Data Analytics
Subgraph Matching for High-Throughput DNA-Aptamer Secondary Structure Classification and Machine Learning Interpretability (Case No. 2025-104)
Intro Sentence: UCLA researchers in the Department of Mathematics have developed machine learning methods to rapidly identify novel aptamer sequences for target binding to accelerate highly-accurate diagnostic and therapeutic development. Background: Aptamers are single-stranded nucleotide polymers that bind with high affinity to targets such as...
Published: 8/19/2025   |   Updated: 7/15/2025   |   Inventor(s): Andrea Bertozzi, Anne Andrews, Matthew Tyler, Paolo Climaco, Noelle Mitchell
Keywords(s): Advanced Computing / AI, advanced computing methods, Aptamers, Artifical Intelligence (Machine Learning, Data Mining), artificial intelligence/machine learning models, bioinformatics pipeline, cancer target, clustering, computational efficiency, computational efficiency and analysis, design software, DNA clustering, DNA oligomer, DNA Sequencing, Drug, Drug Delivery, Drug Development, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, interpretability, pipeline, large-scale parallelization, Machine Learning, machine learning modeling, motif structures, open source, open source code, OpenAI, Pharmaceutical Drug, protein classification, secondary structure, SELEX, sequences of interest, single strand DNA sequences, Software, Software & Algorithms, Software Development Tools, Software-enabled learning, subgraph matching, target binding, target detection, Targeted Therapy, Targets And Assays, tissue targeting accuracy
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Screening Libraries, Platforms, Platforms > Drug Delivery, Diagnostic Markers > Targets And Assays, Diagnostic Markers, Software & Algorithms > Bioinformatics
iPSCs derived from endometriosis and PCOS patients
NU 2025-155 INVENTORS Ji-Yong Kim* Teresa Woodruff SHORT DESCRIPTION Induced pluripotent stem cells (iPSCs) were generated from peripheral blood mononuclear cells (PBMCs) of women diagnosed with endometriosis or polycystic ovary syndrome (PCOS). BACKGROUND Endometriosis and PCOS are complex, multifactorial reproductive disorders that affect...
Published: 3/25/2026   |   Updated: 7/14/2025   |   Inventor(s):  
Keywords(s): Cell Line, Drug screening, Obstetric/Gynecological, Stem cell
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Functionalized lipid nanoparticles
NU 2022-184 INVENTORS Neha Kamat* Justin Alexander Peruzzi* Timothy Vu* SHORT DESCRIPTION This technology facilitates the rapid expression and conjugation of therapeutic proteins to nanoparticles, creating highly specific drug delivery systems that can be generated swiftly and cost-effectively. BACKGROUND In recent years, there...
Published: 4/13/2026   |   Updated: 2/28/2025   |   Inventor(s):  
Keywords(s): Drug delivery, Drug screening, HTS - High-throughput screening, Nanoparticle, Nanotechnology, Research tool, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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