Search Results - medical+diagnostics

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Brain Cancer: Novel Prognostic Method and Therapeutic Target for Glioblastoma

Advantages: A precision-guided method for identifying glioblastoma-related genes that improves assessment of the current prognostic biomarker Enables the identification of potential novel therapeutic targets: GLP1R agonists, which are already used for managing obesity and type 2 diabetes, could be explored as treatments for GBM Broader Applications:...

Published: 3/24/2025 | Inventor(s): George Blanck, Teresa Thomas

Keywords(s): Cancer Diagnostics, Medical Diagnostics, Oncology, Therapeutics

Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Oncology, Technology Classifications > Medical > Therapeutics

Novel Anti- Aggregation Therapeutic Targets Against Cystic Fibrosis Caused by Pseudomonas Aeruginosa

Advantages: Therapeutic Targets: Identified essential genes in Pa aggregate formation that can be potentially targeted with therapeutics Improved Infection Model: use of synthetic CF sputum media that closely mimics the physical and nutritional environment of CF sputum Potential for Broader Applications: can be extended to other bacterial species...

Published: 2/21/2025 | Inventor(s): Sophie Darch

Keywords(s): Medical Devices, Medical Diagnostics, Therapeutics

Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Medical Diagnostics

New Target for Heart Failure Therapies: Modifying MRPS5/ATF4 Signaling in Cardiomyocytes

Advantages: Identification of MRPS5 as a Therapeutic Target: Reduction of MRPS5 expression stimulates cardiomyocyte proliferation and enhances heart function Discovery of the MRPS5 signaling axis: Decreased MRPS5 enhances ATF4 and Knl1, which promote cardiomyocyte, boosting cardiac recovery after myocardial injury Improved Survival and Cardiac...

Published: 1/17/2025 | Inventor(s): Da-Zhi Wang, John Mably

Keywords(s): Biotechnology, Cardiological Diseases Treatment, Cell & Tissue Culture & Engineering, Medical Diagnostics, Pharmaceuticals

Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Pharmaceuticals

3D Printed Swab for Diagnostic Testing

Advantages: 3D-printed swab comprising a shaft and a plurality of protrusions, that can be manufactured at high capacity with low potential for contamination. 3D-printed swabs can be manufactured with various tip shapes and stem lengths to help optimize sample collections from different targeted locations. 3D printing allows tip diameters...

Published: 7/30/2024 | Inventor(s): Summer Decker, Jonathan Ford, Michael Teng, Kami Kim, Todd Hazelton, John Sinnott, Todd Goldstein

Keywords(s): Medical Devices, Medical Diagnostics

Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Medical Devices

AI-Driven Magnetic Respiratory Sensor for Real-Time Monitoring of Respiratory Diseases Like COVID-19

Advantages: An AI-assisted contactless device that measures a patient’s breathing pattern and provides early and rapid detection of COVID-19 respiratory symptoms, in under 5 minutes. The ultrahigh sensitivity enables real-time monitoring of abnormal variations in a patient’s breath across multiple stages of disease. The portable...

Published: 7/15/2024 | Inventor(s): Manh-Huong Phan, Kee Young Hwang, Valery Ortiz Jimenez, Baleeswaraiah Muchharla

Keywords(s): Artificial Intelligence, Medical Diagnostics, Respiratory Diseases

Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Respiratory

Object-Detecting Deep Learning for Multi-Event Electrochemical Data (Case No. 2024-088)

Summary: UCLA researchers in the Department of Chemistry and Biochemistry developed a custom-designed deep learning architecture for object detection and mechanisms classification to streamline the experimental design of cyclic voltammograms. Background: Cyclic voltammetry, a widely used electrochemical test, serves as a crucial tool in understanding...

Published: 2/14/2025 | Inventor(s): Chong Liu, Quanquan Gu, Benjamin Hoar, Weitong Zhang, Yuanzhou Chen

Keywords(s): 2D ultrasound imaging, Artifical Intelligence (Machine Learning, Data Mining), artificial electromagnetic materials, bioelectronics, Biomaterial, electrochemical sensors, Electronics & Semiconductors, Lithium Battery, Lithium-Ion Battery, Machine Learning, Materials, Medical Devices and Materials, Medical diagnostics, Pharmaceutical Drug, Pharmaceutical testing, Rechargeable Battery, zzenergy storage

Category(s): Electrical > Electronics & Semiconductors, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Storage, Energy & Environment > Water Monitoring & Treatment, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical > Signal Processing

Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....

Published: 2/14/2025 | Inventor(s): Aydogan Ozcan, Hyouarm Joung, Hyun-June Jang, Junhong Chen

Keywords(s): Biomarker, biomarkers, Biomaterial, Biosensor, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Electrical, Electrical Engineering, electrically-mediated sensing, electrochemical sensors, enzyme functionalization, field-effect transistors (FETs), Medical diagnostics, multiplexed analysis, Point Of Care, point-of-care, porous media, sample matrix effects, transistors

Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms, Platforms > Diagnostic Platform Technologies

Frequency Domain Diffuse Correlation Spectroscopy

Advantages: Robust simultaneous quantitative measurement of tissue blood flow and absorption, ensuring reliability and enabling easy cross-subject comparisons for versatility. Single source source-detector separation measurement, reducing the size of the optical probe significantly for portability. Simplifies electronics by eliminating the...

Published: 3/6/2024 | Inventor(s): Ashwin Parthasarathy, Sadhu Moka, Abdul Mohaimen Safi

Keywords(s): Biotechnology, Medical Diagnostics, Spectroscopy

Category(s): Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Medical Imaging, Technology Classifications > Medical > Medical Devices, Technology Classifications > Electronics > Spectroscopy

Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)

Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...

Published: 3/20/2025 | Inventor(s): Eleazar Eskin, Valerie Arboleda

Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing

Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics

Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)

Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...

Published: 2/14/2025 | Inventor(s): Dino Di Carlo, Michael Bogumil

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Flow Cytometry, Medical diagnostics

Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Chemical > Emulsions, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

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