Search Results - research+tool

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Rapid Nanomechanical Diagnostic Assay for SARS-CoV-2 and Other Pulmonary Diseases Detection
NU 2021-142 INVENTORS Gajendra Shekhawat* Vinayak Dravid SHORT DESCRIPTION This invention introduces a nanomechanical diagnostic assay leveraging microcantilevers for the rapid and specific detection of SARS-CoV-2 antigens, achieving results in under 10 minutes with high sensitivity and selectivity. BACKGROUND Rapid detection of respiratory...
Published: 3/2/2025   |   Inventor(s):  
Keywords(s): COVID-19, Diagnostics, Pulmonary disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
CRISPR-Mediated Cleavage of Enzyme-Oligonucleotide Conjugates for Detection of Target Analytes
CRISPR-Mediated Cleavage of Enzyme-Oligonucleotide Conjugates for Detection of Target Analytes NU 2021-068 INVENTORS Chad Mirkin* Devleena Samanta Sasha Ebrahimi SHORT DESCRIPTION This technology leverages CRISPR-mediated cleavage of enzyme-oligonucleotide conjugates to enable sensitive, colorimetric detection of target analytes without the...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): COVID-19, Diagnostics, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Electrochemical Polymer Pen Lithography for High-Throughput Nano/Micro-Patterning
NU 2020-243 INVENTORS Chad Mirkin* Eun Bi Oh Rustin Golnabi David Walker SHORT DESCRIPTION Electrochemical Polymer Pen Lithography (ePPL) is a novel lithographic technique that enables high-throughput nano- to micro-scale patterning of metallic inks using a hydrogel pen array integrated into a three-electrode cell. BACKGROUND ...
Published: 2/5/2025   |   Inventor(s):  
Keywords(s): 3D Printing/Additive Manufacturing, Devices, Engineering, Lithography, Research tool
Category(s): Physical Sciences > Materials and Industrial Processes
Single Objective Oblique Plane Imaging System
NU 2018-182 INVENTORS Yevgenia Kozorovitskiy* Manish Kumar SHORT DESCRIPTION A novel oblique plane imaging system utilizing a reduced number of objectives to enable the use of low numerical aperture (NA) objectives, thus achieving a compact and cost-effective design while maintaining high-quality imaging performance. BACKGROUND Traditional...
Published: 2/5/2025   |   Inventor(s):  
Keywords(s): 3D imaging, Engineering, Imaging, Microscopy, Optics, Research tool
Category(s): Physical Sciences > Engineering & Technology
Borophene Tubes
Nanotubes directly synthesized from atomically thin sheets of borophene to adopt multiple structures with high thermal and electrical conductivity. Background: Borophene nanotubes (BNT) have been a synthetic goal for decades based on predictions of their usefulness in energy storage and generation. BNTs offer options for carbon nanotubes applications,...
Published: 2/21/2025   |   Inventor(s): Paras Prasad, Mark Swihart, Pranay Ranjan, Devendra Negi, Amitava Banerjee, Shahzad Ahmad, Moin Siddiqui, Arshiya Ansari, Ghanshyam Varshney
Keywords(s): Chemistry, Featured, Materials & Chemicals, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Materials and Chemicals, Technology Classifications > Engineering
TauSeeK: Disease Specific Tau Protein Fibrils & Seeding Proteins
NU2024-139 INVENTORS Austin Dubose Michael Vigers Andrew Longhini Vishnu Vijayan Kenneth Kosik Sam Lobo Peter C. Ryffel Songi Han* SHORT DESCRIPTION Compositions, kits, and methods for generating synthetic miniature tau peptides and fibrils, and synthetic full-length pathogenic tau fibrils. BACKGROUND A major hallmark of several neurodegenerative...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Neurodegenerative disease, Research tool, Synthetic biology
Category(s): Life Sciences > Therapeutics
A Protein Fusion Approach for Cell Free Production and Purification of Tagless Therapeutic Hormones
NU 2021-182 INVENTORS Michael C. Jewett* Ariel N. Thames Madison A. DeWinter Weston K. Kightlinger BACKGROUND Sensitive biologic medicines can be difficult to safely deliver due to cold chain and infrastructure constraints. Point-of-care drug manufacturing could circumvent these challenges since medicines could be produced locally and...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Continuous Ammonia Production from Air
An integrated system with a cascading plasma electrochemical process to generate ammonia at room temperature and pressure, using water as the proton source, significantly lowering the carbon footprint while providing the highest ammonia production rate among the reported literature. Background: Ammona synthesis is a fundamental reaction for the production...
Published: 1/28/2025   |   Inventor(s): Yuguang Li, Xiaoli Ge
Keywords(s): Chemistry, Energy, Environment, Featured, Instrumentation, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications > Engineering, Technology Classifications > Energy, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Research Tools and Reagents
Therapy for non-alcoholic fatty liver disease
NU 2019-095 INVENTORS Grant Barish* Meredith Sommars Madhavi Senagolage SHORT DESCRIPTION Targeting B cell lymphoma protein 6 (BCL6) with small molecule inhibitors as a therapeutic strategy for non-alcoholic fatty liver disease. BACKGROUND Obesity is widely prevalent and linked to multiple comorbidities including metabolic dysfunction-associated...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Biomarker, Research tool
Category(s): Life Sciences > Therapeutics
CRISPR Spherical Nucleic Acids
NU 2021-043 INVENTORS Chad A. Mirkin* Chi Huang BACKGROUND The use of CRISPR/Cas9 systems in genome editing has been limited by the inability to efficiently deliver the key editing components to tissues...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Genomics, Nanotechnology, Research tool
Category(s): Life Sciences > Therapeutics
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