Search Results - research+tool

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Safe, Automated, And High Yielding Method For Synthesizing Deoxyoligonucleicguanidines (DNG) Strands
NU 2019-109 SHORT DESCRIPTION Spherical nucleic acids (SNAs) incorporating deoxynucleic guanidine (DNG)-modified oligonucleotides enable improved cellular uptake and intracellular delivery by introducing positively charged backbone modifications. BACKGROUND Oligonucleotide therapeutics, including antisense and RNA interference (RNAi) approaches,...
Published: 5/21/2026   |   Updated: 5/18/2026   |   Inventor(s):  
Keywords(s): Drug delivery, Nucleic Acids, Platform technology, Research tool
Category(s): Life Sciences > Therapeutics
Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations. Background: Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 5/13/2026   |   Updated: 5/13/2026   |   Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
Production of Salivary Gland Epithelial Progenitors and Acinar Organoids
Human iPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function. Background: Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 5/13/2026   |   Updated: 5/13/2026   |   Inventor(s): Stelios Andreadis, Ronel Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays
A Biosensor Engineering Strategy for Improved Cell-based Therapy
NU 2016-174 Inventors Joshua N. Leonard* Kelly A. Schwarz Rachel M. Dudek Short Description A sophisticated multiplexed biosensor system that can activate a downstream promoter to effect diverse custom biological functions. #therapeutics #cellsignaling #healthcare #diagnostictool Background The market for cell-based therapeutics has gained wide...
Published: 5/12/2026   |   Updated: 5/12/2026   |   Inventor(s):  
Keywords(s): Biotechnology, Cell therapy, Research tool, Sensors, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Northwestern Startup: Syenex, Inc.
Northwestern Inventor: Joshua Leonard McCormick School of Engineering Chemical and Biological Engineering Syenex builds bioengineering technologies to unlock the future of human health. Leveraging the power of synthetic biology, we design scalable, precision-engineered components, empowering cell and gene therapy developers to cure disease and build...
Published: 5/5/2026   |   Updated: 5/5/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomedical, Drug delivery, Gene therapy, Platform technology, Research tool, Startup with Northwestern IP, Synthetic biology, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics
STING Agonist 8803 for Blood-Brain Barrier Opening in Glioblastoma Treatment
SHORT DESCRIPTION Chemical compound that opens the blood-brain barrier to enhance delivery of therapeutics for treating glioblastoma. INVENTORS Amy Heimberger* Northwestern University Feinberg School of Medicine, Department of Neurological Surgery * Principal Investigator NU Tech ID: NU 2025-212 IP...
Published: 5/7/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Adjunct therapy, ALS - Amyotrophic Lateral Sclerosis, Animal Model, Autoimmune disease, Bladder cancer, Brain cancer, Breast cancer, Cancer Treatment, Cancer/Oncology, Cervical cancer, CNS - Central Nervous System, Colon cancer, Drug delivery, Endometrial cancer, Gastric cancer, GBM - Glioblastoma, Head and neck cancer, Immunology, Immunotherapy, Liver cancer, Lung cancer, MS - Multiple Sclerosis, Neurodegenerative disease, Neurologic disease, Ovarian cancer, Pancreatic cancer, PD - Parkinson's Disease, Prostate cancer, Repurposed Drugs, Research tool, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Fluorescent Peptides for Membrane Tension Reporting and Biomarkers
A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension. Background: The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...
Published: 5/15/2026   |   Updated: 4/15/2026   |   Inventor(s): Thomas Suchyna, Sergei Sukharev
Keywords(s): Featured, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials
Antibodies for treatment of coronavirus disease
NU 2023-247 INVENTORS Huiping Liu* Deyu Fang* Hannah Mubarak Andrew Hoffmann Nurmaa Dashzeveg Lamiaa El-Shennawy Juncheng Wei Wuwei Tan Yang Shen SHORT DESCRIPTION Computationally redesigned antibodies targeting SARS-CoV-2 for treating COVID-19. BACKGROUND The continuous evolution of SARS-CoV-2 has allowed the virus to escape most therapeutic...
Published: 2/26/2026   |   Updated: 2/26/2026   |   Inventor(s):  
Keywords(s): Antibody, Artificial Intelligence & Machine Learning, Biologic, Infectious disease, Research tool, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
A Rat Model of IgA Nephropathy
NU 2019-196 INVENTORS Jing Jin* Xinfang Xie SHORT DESCRIPTION A novel rat model of IgA nephropathy (IgAN, also known as Berger's disease), enabling reproducible kidney mesangial deposits characteristic of the human disease for therapeutic and diagnostic evaluation. BACKGROUND IgAN, the most common glomerulonephritis worldwide, results...
Published: 4/13/2026   |   Updated: 2/26/2026   |   Inventor(s):  
Keywords(s): Animal Model, Antibody, Drug screening, Immunology, Inflammation, Renal Disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Extracellular vesicles for diagnosis and treatment of breast cancer
SHORT DESCRIPTION Novel methods for detecting cancer through exosome analysis and bioengineered exosomes specifically designed to target cancer stem cells (CSCs). INVENTORS Huiping Liu*, MD, PhD Associate Professor, Pharmacology, Medicine (Hematology and Oncology), Northwestern University Feinberg School...
Published: 2/6/2026   |   Updated: 2/6/2026   |   Inventor(s):  
Keywords(s): Biomarker, Breast cancer, Cancer/Oncology, Diagnostics, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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