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The use of complex or fusion protein of soluble MIC (Smic) and antibody to treat MIC-negative cancer

NU 2019-146 INVENTORS Jennifer Wu* SHORT DESCRIPTION A fusion protein complex comprising soluble MIC and a non-blocking sMIC-neutralizing antibody that effectively activates CD8 T cells for the treatment of MIC-negative cancer. BACKGROUND Effective T cell co-stimulation is critical for durable tumor control, yet many current immunotherapies...

Published: 12/3/2025 | Inventor(s):

Keywords(s): Antibody, Cancer/Oncology, Research tool

Category(s): Life Sciences > Therapeutics

2-(Pyridin-3-yl)quinazoline compounds as glucocerebrosidase modulators

✅ Feedback form for Tech ID 2015-064 PROPOSED TITLE: 2-(Pyridin-3-yl) quinazoline Compounds as Glucocerebrosidase Modulators NU 2015-064 INVENTORS Richard Silverman* Dimitri Krainc Jianbin Zheng SHORT DESCRIPTION Novel substituted quinazoline compounds that modulate glucocerebrosidase activity, offering a promising therapeutic approach for...

Published: 11/18/2025 | Inventor(s):

Keywords(s): Neurodegenerative disease, Neurologic disease, PD - Parkinson's Disease, Research tool, Therapeutics

Category(s): Life Sciences > Therapeutics

Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas

NU 2012-090 INVENTORS Chad Mirkin (Northwestern University, Department of Chemistry)* Keith Brown Shu He Guoliang Liu Xing Liao Wooyoung Shim Abrin Schmucker SHORT DESCRIPTION This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks. BACKGROUND Current...

Published: 11/11/2025 | Inventor(s):

Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools

A Biological Marker for Concussion

NU 2016-016 INVENTORS Nina Kraus* Trent Nicol Travis White-Schwoch SHORT DESCRIPTION This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...

Published: 11/7/2025 | Inventor(s):

Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool

Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools

Flexible Nanophotonic Cavity-Enhanced Infrared Photodetectors Employing Double Quantum Wells

Double-quantum-well infrared photodetectors (DQWIPs) integrated with nanophotonic cavities enable highly responsive mid-infrared detection through enhanced intersubband absorption in the thin semiconductor heterostructure. Additionally, the technology is compatible with flexible substrates. Background: Quantum Well Infrared Photodetectors (QWIPs)...

Published: 11/6/2025 | Inventor(s): Peter Liu, Puspita Paul

Keywords(s): Featured, Imaging: Medical Imaging, Instrumentation, Night vision and thermal imaging, Optics, Research Tool, Sensors, Surveillance, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Electronics, Technology Classifications > Engineering, Technology Classifications > Semiconductor Devices and Manufacturing

Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening

NU 2010-131 INVENTORS Vadim Backman* Dhwanil Damania Dhananjay Kunte Hariharan Subramanian Hemant Roy Mart De La Cruz SHORT DESCRIPTION This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer. BACKGROUND Colorectal...