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Search Results - biomarker
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Sensitive and Robust Biosensing Using Plasmonic Enhancement of Fluorescence by Rapid Thermal Annealed Silver Nanostructures
Advantages: Enhances cancer
biomarker
sensitivity Scalable production methods Enables low-concentration detection Ideal for portable diagnostics Summary: In cancer diagnostics, a major challenge is the detection of biomarkers at extremely low concentrations, particularly at the nanogram per milliliter (ng/ml) level, which is crucial for...
Published: 9/17/2024
|
Inventor(s):
Shuangming Li
,
Venkat Bhethanabotla
Keywords(s):
Biomarker
,
Cancer Diagnostics
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Electronics > Nanotechnology
,
Technology Classifications > Cancer > Cancer Diagnostics
,
Technology Classifications > Medical > Medical Nanotechnology
,
Technology Classifications > Medical > Medical Diagnostics
Therapy for non-alcoholic fatty liver disease
NU 2019-095 INVENTORS Grant Barish* Meredith Sommars Madhavi Senagolage SHORT DESCRIPTION Targeting B cell lymphoma protein 6 (BCL6) with small molecule inhibitors as a therapeutic strategy for non-alcoholic fatty liver disease. BACKGROUND Obesity is widely prevalent and linked to multiple comorbidities including metabolic dysfunction-associated...
Published: 7/3/2024
|
Inventor(s):
Keywords(s):
Biomarker
,
Research tool
Category(s):
Life Sciences > Therapeutics
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of
biomarker
s in bodily fluids....
Published: 4/1/2024
|
Inventor(s):
Aydogan Ozcan
,
Hyou-Arm Joung
,
Hyun-June Jang
,
Junhong Chen
Keywords(s):
Biomarker
,
biomarker
s
,
Biomaterial
,
Biosensor
,
Computer-Aided Diagnosis
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Electrical
,
Electrical Engineering
,
electrically-mediated sensing
,
electrochemical sensors
,
enzyme functionalization
,
Medical diagnostics
,
multiplexed analysis
,
Point Of Care
,
point-of-care
,
porous media
,
sample matrix effects
,
transistors
Category(s):
Electrical
,
Electrical > Sensors
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Platforms
,
Platforms > Diagnostic Platform Technologies
Novel Method of Cancer Diagnosis by Label-Free Spectroscopic Imaging of Cell Membrane
Advantages Utilizing rough aluminum substrates reduces expenses compared to traditional noble metals in cancer diagnostics. Our method ensures safety by using biocompatible aluminum substrates, eliminating the toxicity of noble metals. Atomic force microscopy (AFM) enhances precision, providing reliable Raman signal calibration for accurate...
Published: 3/5/2024
|
Inventor(s):
Dmitri Voronine
,
Phat Huynh
,
Dang Nguyen
,
Grace Binder
,
Sharad Ambardar
Keywords(s):
Biomarker
,
Cancer Diagnostics
,
Spectroscopy
Category(s):
Technology Classifications > Medical > Medical Devices
,
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Cancer > Cancer Diagnostics
,
Technology Classifications > Electronics > Spectroscopy
Mouse Model for Specific Proteomic Labeling
Application Proteomic labeling (labeling of proteins). Key Benefits Method can be used to express TurboID in any cell type. The mouse line can be crossed with any existing Cre line and can be extended to any organ/tissue system. Detection of labeled
biomarker
s can be identified in biofluids as biomarkers of cell specific disease mechanisms. Can...
Published: 7/30/2024
|
Inventor(s):
Srikant Rangaraju
,
Nicholas Seyfried
,
Sruti Rayaprolu
Keywords(s):
Animal Model
,
Biomarker
Category(s):
TechPub Algolia > Research Tools
Markers Predictive of Therapeutic Response in B-cell Malignancies
Application Test to detect NF-kB2 breaks to guide treatment with proteasome inhibitors and its use with other therapeutic agents. Key Benefits Improved the prediction model to determine which patients are more likely to respond to bortezomib treatment. Improved the efficacy of treatment for patients with multiple myeloma and lymphomas. Market...
Published: 7/30/2024
|
Inventor(s):
Leon Bernal-Mizrachi
Keywords(s):
Biomarker
,
Oncology
Category(s):
TechPub Algolia > Diagnostics
Assays for Labeling and Evaluating Lysine Methylation
Application A life science tool for evaluating protein lysine methylation for drug discovery and disease research. Key Benefits Highly specific labeling method for post-translational methylated lysine. Potential to improve the understanding of protein lysine methylation and help develop new drugs to block its interactions across several disease...
Published: 8/22/2024
|
Inventor(s):
Monika Raj
,
Ogonna Nwajiobi
Keywords(s):
Assay
,
Biomarker
Category(s):
TechPub Algolia > Diagnostics
ANTIBODIES TO IL1RN AS MARKERS OF PRETERM BIRTH
ANTIBODIES TO IL1RN AS MARKERS OF PRETERM BIRTH Researchers at CZ Biohub SF and UCSF have discovered a novel
biomarker
of pre-term birth. Little is known about pre-term delivery risk and more specifically the immunological processes that allow for tolerance of a semi-allogenic fetus within the mother’s body. However, the processes that govern...
Published: 8/17/2023
|
Inventor(s):
Elze Rackaityte
,
Joseph DeRisi
Keywords(s):
Antibody
,
Biomarker
,
Preterm Delivery Risk
Category(s):
Technology Classifications > Biology
A Viral Exposure Signature to Define and Detect Early Onset Hepatocellular Carcinoma
Abstract: Early detection of liver cancer, such as hepatocellular carcinoma (HCC), is key to improve cancer-related mortality. More than 800,000 people are diagnosed with this cancer each year throughout the world. Liver cancer is also a leading cause of cancer deaths worldwide, accounting for more than 700,000 deaths each year. Currently, millions...
Published: 4/8/2024
|
Inventor(s):
Xin Wei Wang
,
Jinping Liu
,
Wei Tang
Keywords(s):
Biomarker
,
HCC
,
hepatocellular carcinoma
,
Liver cancer
,
viral infection
,
Wang
Category(s):
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Oncology
,
Application > Diagnostics
Tumor Tissues Harboring Mutations in cAMP-specific Phosphodiesterases
Abstract: The National Institute of Child Health and Human Development (NICHD), Division of Intramural Research, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize clinical samples with genetic mutations associated with endocrine tumors. Researchers at the...
Published: 4/8/2024
|
Inventor(s):
Constantine Stratakis
,
Anelia Horvath
,
Kit Man Tsang
Keywords(s):
Biomarker
,
Clinical Samples
,
Endocrine Tumors
,
Phosphodiesterase Inhibitors
,
Research Tools
Category(s):
TherapeuticArea > Oncology
,
Application > Research Materials
,
Collaboration Sought > Licensing
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