Search Results - biomaterials

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Removing Per- and Polyfluorinated (PFAS) from the Environment
An effective, green, scalable, and sustainable approach for removing chemical contaminants from drinking water and groundwater. Background: Poly- and perfluoroalkyl substances (PFAS) are persistent manmade chemicals that have been widely used since the 1950s. Across the United States, hundreds of sites have been contaminated by these anthropogenic...
Published: 4/1/2025   |   Inventor(s): Yanna Liang, Weilan Zhang
Keywords(s): biological materials, biomaterials, cleaning, cleaning technology, destruction, fluid management, hydrothermal liquefaction, PFAS, phytoremediation, Technologies
Category(s): Technology Classifications > Materials and Chemicals, Campus > University at Albany
Sliding Bioactive Peptides for Therapeutic Delivery
NU 2023-142 INVENTORS Samuel I. Stupp* Federico Lancia Madison E. Strong Matias A. Alvarez-Saavedra SHORT DESCRIPTION This technology involves the design and engineering of peptide amphiphile nanofibers that deliver bioactive peptides both extra- and intra-cellularly. The bioactive peptides can slide along these structures...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Biomaterials, Drug delivery
Category(s): Life Sciences > Therapeutics
Ion-Doped Supramolecular Nanostructures
NU 2023-006 INVENTORS Samuel Stupp* Zaida Alvarez Pinto Ivan Ramos Sasselli Nicholas Allen Sather Zois Syrgiannis SHORT DESCRIPTION This technology involves the development of ion-doped peptide amphiphiles (IDPAs) that form supramolecular nanostructures capable of enhancing neural development and membrane excitability...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Biomaterials, Drug delivery, Nanomaterials
Category(s): Physical Sciences > Materials and Industrial Processes
Peptide Amphiphiles for Sonic Hedgehog Regulation of Pelvic Nerves for Treatment of Stress Urinary Incontinence and Erectile Dysfunction
NU 2018-075, 2018-076, 2018-077 INVENTORS Caroline Podlasek Kevin McVary Daniel Harrington Samuel Stupp* SHORT DESCRIPTION Novel peptide amphiphile (PA) nanofiber hydrogel is used to deliver sonic hedgehog (SHH) protein to nerves of the major pelvic ganglia and the rhabdospincter as a treatment for erectile dysfunction and urinary incontinence. ...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Biomaterials, Drug delivery, Materials, Therapeutics
Category(s): Life Sciences > Therapeutics
Aqueous Peptide Programming of Organic Ferroelectric Materials
NU2023-005 INVENTORS Samuel Stupp* Yang Yang SHORT DESCRIPTION Novel peptide material with precise nanoscale assembly, versatility in morphology, enhanced ferroelectric properties, high-temperature and electrochemical performance. BACKGROUND Poly(vinylidene fluoride) (PVDF) is the leading organic ferroelectric material with multiaxial ferroelectricity,...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Biomaterials, Materials
Category(s): Physical Sciences > Materials and Industrial Processes
Enhanced Delivery and Efficacy of Antisense Drugs via Covalently Linked Nanodisc Scaffolds
Application A synthetic nanodisc (ND) scaffold for delivering antisense oligonucleotides (ASOs) for the treatment of disease. Key Benefits Improved cellular uptake and protein suppression using antisense oligos. Longer ASO half-life compared to other ASO delivery methods. Potential to overcome the delivery and efficacy challenges using ASOs for...
Published: 4/3/2025   |   Inventor(s): Khalid Salaita, Radhika Sharma
Keywords(s): Biomaterials, Cardiology and Vascular Devices, Chemistry, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery, TechPub Algolia > Micro and Nanotechnology
Biodegradable and Biocompatible Bioactive-based Polymers - Versatile Platform Technology
Invention Summary: The Uhrich group has developed various biodegradable polymers that chemically incorporate bioactive molecules, such as nonsteroidal anti-inflammatory drugs (e.g., salicylic acid), antioxidants (e.g., ferulic acid) and antimicrobials (e.g., carvacrol). Bioactive molecules are incorporated into polymer backbones through labile linkages,...
Published: 11/1/2024   |   Inventor(s): Kathryn Uhrich, Jonathan Faig, Kervin Smith
Keywords(s): Antibacterial, Bioengineering scaffolds, Biomaterials, Drug Delivery, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Fractional Catalytic Pyrolysis and Protein Adhesives Production from Biomass
Fractional catalytic pyrolysis (FCP) is a novel process for the conversion of biomass components into desirable products without a need for secondary separation techniques. FCP is applicable to whole biomass feedstocks, biomass-to-ethanol residues and organosolv pulping residues. Potential products include adhesives, biohydrogen, cresols and phenols....
Published: 10/27/2023   |   Inventor(s): Foster Agblevor
Keywords(s): Biomaterials, Mechanical & Manufacturing, Renewable Energy - Biomass
Category(s): Technology Classifications > Agriculture, Technology Classifications, Technology Classifications > Chemicals/Materials
Customized Telodendrimer Nanocarriers for Targeted Drug Delivery for Disease Treatments
A suite of nanocarrier technologies that provide targeted drug delivery of hydrophobic and hydrophilic drugs to specific disease sites. Background: Delivery of therapeutic and diagnostic compounds is limited by the lack of efficient carriers to improve in vivo stability, selectivity as well as to reduce immunogenicity. Conventional nanocarrier design...
Published: 4/1/2025   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, affinity alkylating agent, autoimmune, autoimmune disease, bioactivity, biocompatible, biomaterials, chemical formulation, chemistry, cisplatin, combintorial conjugated dendrimer, dendritic drug delivery, drug delivery component, drug formulation, Featured, graft rejection, hydrophilic drug, hydrophobic drug, immune modulating, immunogenicity inflammation, inflammatory, inflammatory, inflammatory, inflammatory, inflammatory response, inflammatory response, intracellular delivery, methotrexate, moieties, nanocarriers, nanomedicine, nanoparticle, nanoparticle drug delivery, nanoparticle-enhanced delivery, nanotherapy, polyethylene glycol, polymyxin, targeted biologics delivery, targeted delivery, targeted drug delivery, targeted therapeutic delivery, targeting drug, Technologies, therapeutic drug, topoisomerase, vitamin E
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Novel Delivery System for BMP4 for the Treatment of Pediatric High-Grade Glioma
NU 2020-051 INVENTORS Samuel I. Stupp SHORT DESCRIPTION A novel delivery system for bone morphogenetic protein 4 utilizing nanotechnology. BACKGROUND Pediatric high-grade glioma (HGG) is among the most formidable cancer occurring in childhood patients. Current treatments include surgery followed by chemo- and radiation therapy but, these have...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Biomaterials, Cancer/Oncology, Drug delivery, Drug delivery, Nanomaterials
Category(s): Life Sciences > Therapeutics
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