Search Results - biomaterials

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Enhanced Delivery and Efficacy of Antisense Drugs via Covalently Linked Nanodisc Scaffolds
Application A synthetic nanodisc (ND) scaffold for delivering antisense oligonucleotides (ASOs) for the treatment of disease. Key Benefits Improved cellular uptake and protein suppression using antisense oligos. Longer ASO half-life compared to other ASO delivery methods. Potential to overcome the delivery and efficacy challenges using ASOs for...
Published: 8/22/2024   |   Inventor(s): Khalid Salaita, Radhika Sharma
Keywords(s): Biomaterials, Cardiovascular, Chemistry, Oncology
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery, TechPub Algolia > Micro and Nanotechnology
Biodegradable and Biocompatible Bioactive-based Polymers - Versatile Platform Technology
Invention Summary: The Uhrich group has developed various biodegradable polymers that chemically incorporate bioactive molecules, such as nonsteroidal anti-inflammatory drugs (e.g., salicylic acid), antioxidants (e.g., ferulic acid) and antimicrobials (e.g., carvacrol). Bioactive molecules are incorporated into polymer backbones through labile linkages,...
Published: 4/17/2024   |   Inventor(s): Kathryn Uhrich, Jonathan Faig, Kervin Smith
Keywords(s): Antibacterial, Bioengineering scaffolds, Biomaterials, Drug Delivery, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Fractional Catalytic Pyrolysis and Protein Adhesives Production from Biomass
Fractional catalytic pyrolysis (FCP) is a novel process for the conversion of biomass components into desirable products without a need for secondary separation techniques. FCP is applicable to whole biomass feedstocks, biomass-to-ethanol residues and organosolv pulping residues. Potential products include adhesives, biohydrogen, cresols and phenols....
Published: 10/27/2023   |   Inventor(s): Foster Agblevor
Keywords(s): Biomaterials, Mechanical & Manufacturing, Renewable Energy - Biomass
Category(s): Technology Classifications > Agriculture, Technology Classifications, Technology Classifications > Chemicals/Materials
Removing Per- and Polyfluorinated (PFAS) from the Environment
An effective, green, scalable, and sustainable approach for removing chemical contaminants from drinking water and groundwater. Background: Poly- and perfluoroalkyl substances (PFAS) are persistent manmade chemicals that have been widely used since the 1950s. Across the United States, hundreds of sites have been contaminated by these anthropogenic...
Published: 3/27/2024   |   Inventor(s): Yanna Liang, Weilan Zhang
Keywords(s): biological materials, biomaterials, cleaning, cleaning technology, destruction, fluid management, hydrothermal liquefaction, PFAS, phytoremediation, Technologies
Category(s): Technology Classifications > Materials and Chemicals, Campus > University at Albany
Customized Telodendrimer Nanocarriers for Targeted Drug Delivery for Disease Treatments
A suite of nanocarrier technologies that provide targeted drug delivery of hydrophobic and hydrophilic drugs to specific disease sites. Background: Delivery of therapeutic and diagnostic compounds is limited by the lack of efficient carriers to improve in vivo stability, selectivity as well as to reduce immunogenicity. Conventional nanocarrier design...
Published: 9/24/2024   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, affinity alkylating agent, autoimmune, autoimmune disease, bioactivity, biocompatible, biomaterials, chemical formulation, chemistry, cisplatin, combintorial conjugated dendrimer, dendritic drug delivery, drug delivery component, drug formulation, Featured, graft rejection, hydrophilic drug, hydrophobic drug, immune modulating, immunogenicity inflammation, inflammatory, inflammatory, inflammatory, inflammatory, inflammatory response, inflammatory response, intracellular delivery, methotrexate, moieties, nanocarriers, nanomedicine, nanoparticle, nanoparticle drug delivery, nanoparticle-enhanced delivery, nanotherapy, polyethylene glycol, polymyxin, targeted biologics delivery, targeted delivery, targeted drug delivery, targeted therapeutic delivery, targeting drug, Technologies, therapeutic drug, topoisomerase, vitamin E
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Nanosphere Size Control by Varying the Ratio of Copolymer Blends
table;telerik-style-name: TableNormal;border-collapse: collapse; } Schematic showing the process of creating drug-loaded nanospheres Invention Summary: Recent advances in nanotechnology have demonstrated the advantages of encapsulating poorly bioavailable drugs in nanometer-sized spheres (nanospheres) and deliver them in a targeted manner....
Published: 2/5/2024   |   Inventor(s): Joachim Kohn, Mariana Reis Nogueira de Lima
Keywords(s): Biomaterials, Drug Delivery, Nanotechnology, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences
Engineered Biomaterials for Vascular Grafts
Application A biomaterial to create grafts for treating babies with congenital heart diseases. Key Benefits A biocompatible material that can be used to reroute blood within the body. Experimental data in animals show the material is biocompatible with no clots, thrombus, or adverse immune reactions. Potential to be used in other cardiovascular...
Published: 7/30/2024   |   Inventor(s): Saimuralidhar (Murali) Padala, Jahnavi Mudigonda
Keywords(s): Biomaterials, Cardiovascular
Category(s): TechPub Algolia > Non-Therapeutics
Novel ChABC formulation with machine learning-guided automation
​ ​ Invention Summary: Spinal cord injury (SCI) leads to the formation of scar tissue. The scarring leads to the toughening of the extracellular matrix, or the cellular environment. One of the major concerns of SCI is the prevention of neuronal connection recovery, which can lead to paralysis or reduced control of the nervous system. For...
Published: 6/13/2024   |   Inventor(s): Adam Gormley, Matthew Tamasi, Shashank Kosuri, Michael Webb, Carlos Borca, Roshan Patel
Keywords(s): Biomaterials, Polymers & Composites, Proteins, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Software & Algorithms, Technology Classifications > Therapeutics
Chameleon-Inspired Strain-Accommodating Smart Skin
Application A flexible smart skin that changes its color in response to heat or sunlight. Key Benefits Strain-accommodating. Thermal and photothermal responsive. Light responsive. Highly stretchable. Market Summary Hydrogels are water-insoluble, three-dimensional networks of polymer chains capable of holding large amounts of water. They are...
Published: 7/30/2024   |   Inventor(s): Khalid Salaita, Yixiao Dong
Keywords(s): Biomaterials, Chemistry
Category(s): TechPub Algolia > Micro and Nanotechnology
Functionalized Collagen Biochips with Core-Shell Structures and Collagen-Mimetic Peptide Nanotubes
Application Synthetic collagen-based biomaterials for therapeutic delivery or drug testing. Key Benefits Synthetic collagen substitute. Capable of formulating into various structures. Free of animal-based contaminants. Able to be spatially patterned. Market Summary Organ failure and tissue defects affect millions of Americans, resulting in...
Published: 8/22/2024   |   Inventor(s): Vincent Conticello, Andrea Merg, Gavin Touponse
Keywords(s): Biomaterials, Enzyme/Protein
Category(s): TechPub Algolia > Micro and Nanotechnology
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