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Patient-Specific Organ Dose Quantification and Optimization for CT

RPI ID: 2020-032-401 Innovation Summary: A computational method enables quantification of organ-specific radiation dose during CT imaging and uses inverse optimization to adjust scan parameters accordingly. The system incorporates patient-specific anatomical models and dose-response data to guide personalized imaging protocols. It supports real-time...

Published: 3/10/2026 | Inventor(s): Pingkun Yan, Birsen Yazici, Xie Xu

Keywords(s): AI workflow, Artificial Intelligence Radiology, Clinical Imaging, computed tomography (CT), CT dosimetry, CT Scanner, deep learning, Dosimetry, Imaging, medical imaging, Nuclear Medicine, Personalized Medicine, Radiology, X-Rays

Category(s): Biotechnology and the Life Sciences

Multipurpose Micro Diffractive- Imaging Magnetooptical System

RPI ID: 2020-019-401 Innovation Summary: A magneto-optical imaging system integrates diffractive optics to enhance spatial resolution and material-specific contrast. The system uses magnetic field modulation and diffractive lensing to visualize magnetic domains and anisotropic structures. It supports micro- and nanoscale imaging and is compatible with...

Published: 3/10/2026 | Inventor(s): Edwin Fohtung

Keywords(s): diffractive, Imaging, laser magnetometry, magnetooptical

Category(s): Computational Science and Engineering

Deep learning for automated, motion-resolved tumor segmentation in radiotherapy

NU2025-264 INVENTORS Mohamed Abazeed* Sagnik Sarkar Peng Thian Troy Teo SHORT DESCRIPTION This invention describes a method for automatically outlining lung tumors for radiotherapy planning. It uses deep learning to precisely identify tumors across breathing cycles, improving accuracy and reducing manual effort. BACKGROUND Accurate tumor...

Published: 2/17/2026 | Inventor(s):

Keywords(s): Artificial Intelligence & Machine Learning, Cancer/Oncology, Diagnostics, Imaging, Lung cancer, Radiotherapy

Category(s): Life Sciences > Healthcare Devices, Tools & IT

Extracellular vesicles for diagnosis and treatment of breast cancer

SHORT DESCRIPTION Novel methods for detecting cancer through exosome analysis and bioengineered exosomes specifically designed to target cancer stem cells (CSCs). INVENTORS Huiping Liu*, MD, PhD Associate Professor, Pharmacology, Medicine (Hematology and Oncology), Northwestern University Feinberg School...

Published: 2/6/2026 | Inventor(s):

Keywords(s): Biomarker, Breast cancer, Cancer/Oncology, Diagnostics, Imaging, Research tool

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools

3D-Printed Microrobots for Magnetic Actuation, Imaging, and Hyperthermia

Executive Summary Microrobots offer transformative potential in biomedical applications, including targeted drug delivery, detoxification, and minimally invasive surgeries. However, two key challenges hinder their clinical translation: achieving scalable and precision fabrication, and enabling non-invasive imaging and tracking within deep biological...

Published: 2/2/2026 | Inventor(s): Jinxing Li, Liuxi Xing

Keywords(s): 3D, Imaging, Medical

Category(s): Medical, Advanced Materials

Monitoring Structural Health Using Diffractive Optical Processors (Case No. 2025-201)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel structural health monitoring system that is highly accurate and cost effective, addressing limitations in current infrastructure and civil health monitoring and a rise in public safety concerns. Background: The need for structural health monitoring...

Published: 12/5/2025 | Inventor(s): Aydogan Ozcan, Ertugrul Taciroglu, Yuntian Wang, Yuhang Li

Keywords(s): 3D structures, Adaptive Optics, AI-generated images and content, all-optical diffractive computing, all-optical transformation, analog computing, analog optical computing, Analogue Electronics, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial-intelligent materials, civil engineering, civil infrastructure, civil monitoring, computational imaging, computational imaging task, Construction, deep diffractive network, Diffraction, diffractive design, diffractive image reconstruction, diffractive network, diffractive processor, diffractive surface, digital image reconstruction, electromagnetic spectrum, Electro-Optics, Image Analysis, Image Processing, Image Resolution, image restoration, image signal processing, Imaging, Infrastructure, Lens (Optics), linear optics, Nanostructure, optical processor, optically-guided structural monitoring, Optics, passive light-matter interactions, security imaging, Signal Reconstruction, Structural health monitoring, structural health monitoring (SHM), structure monitoring, Structures

Category(s): Electrical, Electrical > Signal Processing, Electrical > Imaging, Materials, Materials > Construction Materials, Electrical > Visual Computing, Electrical > Computing Hardware, Electrical > Instrumentation, Energy & Environment, Energy & Environment > Energy Efficiency, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Software & Algorithms > Programs

Summary: UCLA researchers have developed a software algorithm for locally low-rank denoising that improves image quality and diagnostic reliability in multi-coil, multi-contrast MRI by correcting complex noise and preserving fine image details. Background: Magnetic resonance imaging (MRI) is a powerful, non-invasive tool widely used in both research...

Published: 12/1/2025 | Inventor(s): Shu-Fu Shih, Holden Wu

Keywords(s): 3D tissue imaging, AI-guided medical imaging, Biomedical Engineering, Cardiac MRI, Cine MRI, Deep learning MRI, DENSE MRI, Imaging, Magnetic Resonance Imaging, Magnetic Resonance Imaging Carotid Artery Stenosis, Magnetic Resonance Imaging Hypoxia (Medical), Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Microangiopathy, Magnetic Resonance Imaging Pathology, Magnetic Resonance Imaging Spin Polarization, Medical artificial intelligence (AI), Medical Device, Medical Devices and Materials, Medical diagnostics, Medical Imaging, MRI, multiparametric MRI (mpMRI), radial MRI

Category(s): Electrical > Imaging, Electrical > Signal Processing, Life Science Research Tools > Research Methods, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Software & Algorithms > Image Processing, Software & Algorithms

Method and Apparatus for Improving the Signal-To-Noise Ratio in Multi-Dimensional Magnetic Resonance Imaging Data (Case No. 2025-204)

Summary: UCLA researchers have developed a software-based denoising method that makes cardiac MRI images clearer and more reliable, enabling more accurate heart function measurements without requiring longer scan times. Background: Cardiac MRI is a powerful imaging tool for assessing heart health because it can provide detailed pictures of how the...

Published: 11/13/2025 | Inventor(s): Xiaodong Zhong, Shu-Fu Shih, Holden Wu, Kim-Lien Nguyen

Category(s): Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Software & Algorithms > Image Processing, Software & Algorithms

Direct Carrier Fractional Frequency Synthesizer Using a DiCAD-Based Digital-To-Phase Modulator (Case No. 2025-9AA)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a low-noise, DiCAD-based fractional frequency synthesis system that enables fine frequency resolution and enhanced signal stability for millimeter-wave applications. Background: Millimeter-wave (mmW) communication and radar systems demand carrier frequency...

Published: 10/16/2025 | Inventor(s): Mau-Chung Chang, Christopher Chen, Adrian Tang, Jia Zhou

Keywords(s): 5G, Automotive, Bandwidth (Signal Processing), Communications Satellite, efficiency bandwidth products, electrically-mediated sensing, Extremely High Frequency, Frequency conversion, frequency modulation, high frequency electronics, high-frequency signals, high-speed communications, Imaging, millimeter-wave, Millimeterwave network, Quantum Computer, Radar, satellite imaging, Signal-To-Noise Ratio, Telecommunication

Category(s): Electrical, Electrical > Signal Processing, Software & Algorithms > Communication & Networking, Electrical > Electronics & Semiconductors > Circuits, Software & Algorithms

Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening

NU 2010-131 INVENTORS Vadim Backman* Dhwanil Damania Dhananjay Kunte Hariharan Subramanian Hemant Roy Mart De La Cruz SHORT DESCRIPTION This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer. BACKGROUND Colorectal...

Published: 12/9/2025 | Inventor(s):

Keywords(s): Cancer/Oncology, Colon cancer, Diagnostics, Drug screening, Imaging, Research tool

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools

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