Search Results - aptamers

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Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 1/29/2024   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
N-Heterocyclic Carbene Aptamers that Target Drug Delivery to Specific Cancer Cells
Cytotoxic Therapy Targets Malignancies, Avoiding Healthy Cells and Negative Side Effects Caused by Heavy Metal Buildup in OrgansThese aptamers, conjugated with N-heterocyclic carbene metal complexes, deliver therapeutic doses of the cytotoxic metal ion to targeted cancer cells. These complexes avoid toxicity to healthy cells while being highly effective...
Published: 6/27/2021   |   Inventor(s): Adam Veige, Mary Garner, Weijia Niu
Keywords(s): Aptamer crosslinker, aptamers, Cancer Cells Targeting, Cancer Drug Delivery, Cancer Drugs, Cancer Therapeutics, Cancer Therapeutics: Small Molecule, carbene, Cytotoxic, metal ion
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Human Health Care > Therapeutics