Search Results - nanoparticle

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Control of Periprosthetic Joint Infections (Case No. 2021-334)
Summary: UCLA researchers in the Department of Orthopaedic Surgery have developed a non-invasive method to disrupt biofilms on orthopaedic implants and decrease the overall rate of infections. Background: Prosthetic joint infection (PJI) remains a serious complication in hip and knee arthroplasty, with skyrocketing revision rates across all orthopaedic...
Published: 9/23/2024   |   Inventor(s): Fabrizio Billi, Beth Lazazzera
Keywords(s): Biofilm, Cell Growth, electromagnetic, Infection, Nanoparticle, Orthopaedics, Orthopedics and Prosthetics (O & P), Osteo, Prosthetics
Category(s): Medical Devices > Prosthetics, Chemical > Coatings, Adhesives & Inks, Diagnostic Markers > Immunology, Materials > Membranes, Medical Devices > Coatings, Therapeutics > Orthopaedics
Dynamic Extension of the Eyebox for Maxwellian View AR Waveguides (Case No. 2024-163)
Summary: Researchers in the Department of Electrical & Computer Engineering have developed a new metasurface material that improves the size and resolution of augmented reality overlays. Background: Augmented reality (AR) waveguide displays have revolutionized the way users can interact with virtual content overlaid in the real world. High...
Published: 8/16/2024   |   Inventor(s): Chee Wei Wong, Hyunpil Boo
Keywords(s): artificial electromagnetic materials, artificial-intelligent materials, Augmented Reality, augmented reality (AR), bacterial nanocellulose, Carbon Nanotube, Composite Materials, Construction Materials, Extended reality, Functional Materials, intercalated materials, liquid crystal nanofibers, Materials, Medical Devices and Materials, meta materials, metal nanocomposites, metasurfaces, microarchitectured materials, Microfluidics Nanosphere, Mixed Reality, nanobody, nanocomposite scintillators, Nanocomposites, Nanocrystal, nanocrystalline metals, nanodispersion, Nanoelectronics, Nanoemulsion droplet, Nanofiber, nanograined metals, Nanomaterials, Nanoparticle, Nanoparticles, nanophotonic, nanophotonic structures, nanophotonics, Nanosensor, Nanostructure, nanostructured materials, Nanotechnology, Optoelectronic materials, photonic materials, Raw materials supplier, Toxicity Of Nanomaterials, Ultrahard materials/abrasives, Virtual Reality, Virtual Reality Braille Haptic Technology Joule Heating, Virtual Reality Occupational Therapy Exercise Machine, Water Purification, Nanofiltration, Ultrafiltration, zzsemiconducting materials
Category(s): Software & Algorithms, Software & Algorithms > Ar/Vr, Materials, Materials > Composite Materials, Materials > Functional Materials, Materials > Nanotechnology
Nanocomposite Scintillators (Case No. 2024-126)
Summary: UCLA researchers from the Department of Materials Science and Engineering have developed a novel nanocomposite material for high-efficiency radiation detection and monitoring. Background: Scintillators are materials that emit light when they absorb radiation, such as gamma rays or x-rays. The photons generated by the scintillators can...
Published: 5/15/2024   |   Inventor(s): Qibing Pei, Ziqing Han
Keywords(s): adhesive material, Algorithm Optical Coherence Tomography, anode material, artificial electromagnetic materials, artificial-intelligent materials, background radiation, Biomaterial, Biomaterial 3D Printing, bulk material, Composite Material, composite scintillators, Computed tomography, Computerized Tomography scan (CT), Diffraction Tomography, Drug Delivery Microporous Material, fast scintillators, gamma spectroscopy, High resolution computed tomography, high-Z organometallics, hole transporting material, Hyperelastic Material, intercalated materials, material characterization, Materials, meta materials, metal nanocomposites, microarchitectured materials, nanocomposite scintillators, Nanocomposites, Nanomaterials, Nanoparticle, Nanoparticles, nanostructured materials, neutrino detection, Optical Tomography, Optoelectronic materials, photonic materials, positron emission tomography (PET), radiation detection, Raw materials supplier, scintillators, second harmonic generation, Smart Material, Solar Cell Metamaterial, Surgical Instrument Optical Coherence Tomography, suturable biomaterial, X-Ray Computed Tomography
Category(s): Chemical, Chemical > Chemical Sensors, Materials, Materials > Functional Materials
­HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY
­HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY Researchers at Berkeley have developed synthetic cell membranes that are optimized for screening the toxicity and efficacy of lipid nanoparticle formulations in vitro, in a high throughput format. Lipid nanoparticles (LNPs) represent a highly effective and efficient...
Published: 4/22/2024   |   Inventor(s): Markita Landry, Alison Lui
Keywords(s): Nanoparticle, SARS-CoV-2, Vaccine
Category(s): Technology Classifications > Biology
Novel Anti-mesothelin CAR for Use in Engineered Cell Therapies (UCLA Case No. 2023-281)
UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have developed a nanobody-based CAR T cell platform with increased stability and cross-immunogenicity between human and mouse antigens. BACKGROUND: Chimeric antigen receptor (CAR) T-cell therapy makes use of reengineered T cells to target and clear cancer cells....
Published: 6/28/2024   |   Inventor(s): Yvonne Chen
Keywords(s): Cancer, CAR-T cell platform, CAR-T cell therapy, cell engineering, Immunotherapy, Mesothelin, nanobody, Nanoparticle
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Sunlight-Harvesting Windows for Enhanced Power Generation
Nanoparticle-Embedded Glass Redirects Scattered Light to Solar Cells Within Window Frames that Produce Electricity These sunlight-harvesting windows embedded with metal nanoparticles and framed with photovoltaic cells produce four times as much power as other solar windows. In 2014, the United States installed enough solar photovoltaics to power 4...
Published: 11/17/2023   |   Inventor(s): Wei David Wei, Jiangeng Xue
Keywords(s): Harvesting, Infrared Absorption, light scattering, Nanoparticle, Solar Cells, Solar Energy, Transparent
Category(s): Technology Classifications > Engineering > Electrical, Technology Classifications > Engineering > Materials
Ultrafine Platinum Catalysts for Hydrogen Fuel Cells (Case No. 2023-026)
Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel method to synthesize platinum-based catalysts with ultralow base transition metal-oxide content. Background: Ultrafine platinum (Pt)-based catalysts present a promising avenue for achieving exceptional fuel cell activity while minimizing base transition...
Published: 9/17/2024   |   Inventor(s): Yu Huang
Keywords(s): Catalysts, Fuel Cell, Metals, Nanoparticle, Nanoparticles, Nanotechnology, Platinum, transition metal catalysts
Category(s): Materials, Energy & Environment, Energy & Environment > Energy Storage, Energy & Environment > Energy Storage > Fuel Cells, Chemical, Chemical > Catalysts, Chemical > Synthesis, Materials > Nanotechnology
Nanoparticle delivery of lung cancer therapeutic
Abstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in developed countries.  Despite the availability of several synergistic, targeted therapy regiments, the 5-year survival rate for NSCLC is only 15%.  The poor prognosis of NSCLS is due in part to limitations of current treatments, which do not trigger an immune...
Published: 5/22/2024   |   Inventor(s): Dennis Klinman, Takashi Sato (Unable To Locate)
Keywords(s): Immunotherapy, Nanoparticle, Non-small cell lung cancer, NSCLC
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology
Peptide Hydrogels for Rate-Controlled Delivery of Therapeutics
Abstract: Hydrogels represent an attractive controlled drug-delivery system that have been used in various clinical applications, such as: tissue engineering for wound healing, surgical procedures, pain management, cardiology, and oncology. High-water content of hydrogels confers tissue-like physical properties and the crosslinked fibrillar network...
Published: 4/8/2024   |   Inventor(s): Joel Schneider, Stephen Miller, Yuji Yamada, Steven Tau, Julie Hixon, Wenqing Li, Caroline Andrews, Scott Walsh
Keywords(s): DEVICE, IL-7, Nanoparticle, Peptide, Peptide-based Hydrogel, Protein, Schneider, small molecule, T Cell Enhancer, Whole Cell Delivery System
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Immunology
Synthetic Bacterial Nanoparticles as Drug and Vaccine Delivery Vehicles
Abstract: Bacterial spores can be modified to display molecules of interest, including drugs, immunogenic peptides, antibodies and other functional proteins of interest (such as enzymes).  The resulting engineered bacterial spores can provide many useful functions such as the treatment of infections, use as an adjuvant for the delivery of vaccines,...
Published: 5/21/2024   |   Inventor(s): Kumaran Ramamurthi, I-Lin Wu
Keywords(s): Bacterial Spore, Drug Delivery, Nanoparticle, Ramamurthi, SSHEL, Synthetic Spore Husk-encased Lipid Bilayer, VACCINE DELIVERY
Category(s): TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology
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