Search Results - nanoparticle

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Multi-Particle System for Capture and Detection of Cellular and Molecular Analytes (Case No. 2025-267)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel multi-particle system that selectively confines cells and molecular reactions within cavities formed by interacting particles. Background: Screening and selecting cells with specific, beneficial traits has become a vital process in using cell-derived products...
Published: 7/29/2025   |   Inventor(s): Dino Di Carlo, Alyssa Arnheim, Michael Mellody, Yuta Nakagawa, Lily Shang
Keywords(s): Assay, B Cell, barcode, Bioassay, biological assays, Biomarker, biomarkers, Biomaterial, capping particles, CAR-T cell platform, CAR-T cell therapy, cavities, cavity-containing particles, Cell and tissue culture, cell encapsulation, cell engineering, cell imaging, cell mapping, cell sorting, cell type identification, cell-based therapy, centrifugation, confinement, Diagnostic Platform Technologies (E.G. Microfluidics), Digital Microfluidics, Drug, Drug Delivery, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, Immunoassay, Immunoassay Sense (Molecular Biology), Microfluidics, Microfluidics And Mem's, Microfluidics Nanosphere, microparticles, moieties, Nanoparticle, single cell analysis, single cell analysis and testing, Single cell data, single-cell resolution, single-cell trapping
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices, Platforms
High-index Facet Nanocatalysts for Clean Energy Applications
NU2023-109 INVENTORS Chad Mirkin* Bo Shen Zihao Ye SHORT DESCRIPTION A machine learning-guided, high-throughput DFT approach to synthesize high-index facet nanocatalysts with enhanced catalytic performance and broader material applicability. BACKGROUND Nanocrystals with high-index facets offer superior catalytic activity due to their abundance...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Catalyst, Cleantech, Materials, Metals, Nanomaterials, Nanoparticle
Category(s): Physical Sciences > Engineering & Technology
Megalibrary Platform for Oxygen Evolution Reaction Catalysts
NU2023-039 INVENTORS Chad Mirkin* Jin Huang SHORT DESCRIPTION A high-throughput nanoparticle megalibrary platform for discovering multielemental catalysts with enhanced activity and stability for oxygen evolution reactions in electrochemical energy systems. BACKGROUND The oxygen evolution reaction (OER) is a critical reaction in electrochemical...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Chemicals, Cleantech, Materials, Nanomaterials, Nanoparticle, Spectroscopy
Category(s): Physical Sciences > Materials and Industrial Processes
Customized Telodendrimer Nanocarriers for Targeted Drug Delivery for Disease Treatments
A suite of nanocarrier technologies that provide targeted drug delivery of hydrophobic and hydrophilic drugs to specific disease sites. Background: Delivery of therapeutic and diagnostic compounds is limited by the lack of efficient carriers to improve in vivo stability, selectivity as well as to reduce immunogenicity. Conventional nanocarrier design...
Published: 5/13/2025   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, affinity alkylating agent, autoimmune, autoimmune disease, bioactivity, biocompatible, biomaterials, chemical formulation, chemistry, cisplatin, combintorial conjugated dendrimer, dendritic drug delivery, drug delivery component, drug formulation, Featured, graft rejection, hydrophilic drug, hydrophobic drug, immune modulating, immunogenicity inflammation, inflammatory, inflammatory, inflammatory, inflammatory, inflammatory response, inflammatory response, intracellular delivery, methotrexate, moieties, nanocarriers, nanomedicine, nanoparticle, nanoparticle drug delivery, nanoparticle-enhanced delivery, nanotherapy, polyethylene glycol, polymyxin, targeted biologics delivery, targeted delivery, targeted drug delivery, targeted therapeutic delivery, targeting drug, Technologies, therapeutic drug, topoisomerase, vitamin E
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Engineered Lipid Tags for Extracellular Vesicle Loading
NU 2022-178 INVENTORS Neha Kamat* Joshua Leonard* Justin Alexander Peruzzi Taylor Gunnels SHORT DESCRIPTION This technology enhances the loading of protein cargo into extracellular vesicles (EVs) by directing protein association with membrane lipid rafts, utilizing engineered lipid tags for targeted delivery. BACKGROUND Extracellular...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Leveraging Lipid-Protein Interactions to Engineer Spatial Organization in Cell-free Systems
NU 2021-231 INVENTORS Neha Kamat* Justin Alexander Peruzzi Jan Steinkuehler SHORT DESCRIPTION This innovative method enables the control of membrane protein location and distribution in synthetic lipid membranes using lipid-protein interactions, without chemical conjugation, facilitating the development of advanced cell-free systems. BACKGROUND Spatially...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Physical Sciences > Engineering & Technology
Control of Periprosthetic Joint Infections (Case No. 2021-334)
Summary: UCLA researchers in the Department of Orthopaedic Surgery have developed a non-invasive method to disrupt biofilms on orthopaedic implants and decrease the overall rate of infections. Background: Prosthetic joint infection (PJI) remains a serious complication in hip and knee arthroplasty, with skyrocketing revision rates across all orthopaedic...
Published: 2/14/2025   |   Inventor(s): Fabrizio Billi, Beth Lazazzera
Keywords(s): Biofilm, Cell Growth, electromagnetic, Infection, Nanoparticle, Orthopaedics, Orthopedics and Prosthetics (O & P), Osteo, Prosthetics
Category(s): Medical Devices > Prosthetics, Chemical > Coatings, Adhesives & Inks, Diagnostic Markers > Immunology, Materials > Membranes, Medical Devices > Coatings, Therapeutics > Orthopaedics
Dynamic Extension of the Eyebox for Maxwellian View AR Waveguides (Case No. 2024-163)
Summary: Researchers in the Department of Electrical & Computer Engineering have developed a new metasurface material that improves the size and resolution of augmented reality overlays. Background: Augmented reality (AR) waveguide displays have revolutionized the way users can interact with virtual content overlaid in the real world. High...
Published: 2/14/2025   |   Inventor(s): Chee Wei Wong, Hyunpil Boo
Keywords(s): artificial electromagnetic materials, artificial-intelligent materials, Augmented Reality, augmented reality (AR), bacterial nanocellulose, Carbon Nanotube, Composite Materials, Construction Materials, Extended reality, Functional Materials, intercalated materials, liquid crystal nanofibers, Materials, Medical Devices and Materials, meta materials, metal nanocomposites, metasurfaces, microarchitectured materials, Microfluidics Nanosphere, Mixed Reality, nanobody, nanocomposite scintillators, Nanocomposites, Nanocrystal, nanocrystalline metals, nanodispersion, Nanoelectronics, Nanoemulsion droplet, Nanofiber, nanograined metals, Nanomaterials, Nanoparticle, Nanoparticles, nanophotonic, nanophotonic structures, nanophotonics, Nanosensor, Nanostructure, nanostructured materials, Nanotechnology, Optoelectronic materials, photonic materials, Raw materials supplier, Toxicity Of Nanomaterials, Ultrahard materials/abrasives, Virtual Reality, Virtual Reality Braille Haptic Technology Joule Heating, Virtual Reality Occupational Therapy Exercise Machine, Water Purification, Nanofiltration, Ultrafiltration, zzsemiconducting materials
Category(s): Software & Algorithms, Software & Algorithms > Ar/Vr, Materials, Materials > Composite Materials, Materials > Functional Materials, Materials > Nanotechnology
Nanocomposite Scintillators (Case No. 2024-126)
Summary: UCLA researchers from the Department of Materials Science and Engineering have developed a novel nanocomposite material for high-efficiency radiation detection and monitoring. Background: Scintillators are materials that emit light when they absorb radiation, such as gamma rays or x-rays. The photons generated by the scintillators can...
Published: 2/14/2025   |   Inventor(s): Qibing Pei, Ziqing Han
Keywords(s): adhesive material, Algorithm Optical Coherence Tomography, anode material, artificial electromagnetic materials, artificial-intelligent materials, background radiation, Biomaterial, Biomaterial 3D Printing, bulk material, Composite Material, composite scintillators, Computed tomography, Computerized Tomography scan (CT), Diffraction Tomography, Drug Delivery Microporous Material, fast scintillators, gamma spectroscopy, High resolution computed tomography, high-Z organometallics, hole transporting material, Hyperelastic Material, intercalated materials, material characterization, Materials, meta materials, metal nanocomposites, microarchitectured materials, nanocomposite scintillators, Nanocomposites, Nanomaterials, Nanoparticle, Nanoparticles, nanostructured materials, neutrino detection, Optical Tomography, Optoelectronic materials, photonic materials, positron emission tomography (PET), radiation detection, Raw materials supplier, scintillators, second harmonic generation, Smart Material, Solar Cell Metamaterial, Surgical Instrument Optical Coherence Tomography, suturable biomaterial, X-Ray Computed Tomography
Category(s): Chemical, Chemical > Chemical Sensors, Materials, Materials > Functional Materials
­HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY
­HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY Researchers at Berkeley have developed synthetic cell membranes that are optimized for screening the toxicity and efficacy of lipid nanoparticle formulations in vitro, in a high throughput format. Lipid nanoparticles (LNPs) represent a highly effective and efficient...
Published: 4/22/2024   |   Inventor(s): Markita Landry, Alison Lui
Keywords(s): Nanoparticle, SARS-CoV-2, Vaccine
Category(s): Technology Classifications > Biology
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