Search Results - dna+sequencing

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Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)
Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...
Published: 9/17/2024   |   Inventor(s): Eleazar Eskin, Valerie Arboleda
Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing
Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics
2021-255 Benchmarking Computational Doublet-detection Methods For Single-cell RNA Sequencing Data
SUMMARY: UCLA researchers in the Department of Statistics have developed a software to compare existing doublet detection algorithms for Single-Cell RNA Sequencing Data. BACKGROUND: Single-cell RNA sequencing (scRNA-seq) provides the expression profiles of individual cells and is considered the gold standard for defining cell states and phenotypes...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s): Algorithm, DNA Sequencing, Error Detection And Correction, Nucleotide, Polymorphism (Biology), RNA, RNA-Seq, Sequencing, Software, Software & Algorithms
Category(s): Software & Algorithms, Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Software & Algorithms > Programs
Electrically Actuatable Zero-mode Waveguides for High-Throughput pg-Level Sequencing
INV-20008 Background DNA sequencing technologies have undergone tremendous improvements in recent years in throughput and quality. One advantage of single-molecule DNA sequencing technologies is that long DNA molecules can be read in a single run, which greatly facilitates genome assembly and aids in the construction of reference-quality genomes....
Published: 9/10/2024   |   Inventor(s): Meni Wanunu, Mohammadamin Alibakhshi, Fatemeh Farhangdoust
Keywords(s): DNA sequencing, single-molecule
Category(s): Technology Classifications > 1. Life Science > Gene sequencing, Technology Classifications > 1. Life Science, Chemistry, Technology Classifications > 1. Life Science > Biotechnology
High-Resolution Sensor of Biopolymer Sequence and Molecules Based on a Localized Nanopore Electrode Sequencer (LNES)
INV-19043 Background This technology introduces two approaches to polymer sequencing using nanopores in electrically conducting, ion‐intercalating MXene membranes, split into two applications: - The first application of MXene membranes is based on ion transport localization between an ultrathin nanopore composed of intercalated ions (between MXene...
Published: 9/10/2024   |   Inventor(s): Meni Wanunu, Mehrnaz Mojtabavi, Armin Vahid Mohammadi, Majid Beidaghi
Keywords(s): DNA sequencing, Nanopores, Protein sequencing, RNA sequencing, Single-molecule mapping
Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering
Thermostable, Solvent-Tolerant Biocatalyst for Extreme Conditions
Haloarchaeal Inorganic Pyrophosphatase Operates in a Variety of Solvents to Aid DNA Sequencing, PCR, SNP Genotyping, and RNA Synthesis This biocatalyst, or enzyme, accelerates organic synthesis reactions in extreme conditions that available biocatalysts do not tolerate. This thermostable inorganic pyrophosphatase (PPA) developed by University of Florida...
Published: 2/22/2024   |   Inventor(s): Julie Maupin, Nathaniel Hepowit, Lana McMillan
Keywords(s): Biocatalyst, Biotech, Biotechnology, Dna Sequencing, Enzyme, Heat Stable, Inorganic pyrophosphatase, organic synthesis reactions, PCR, RNA synthesis, single-base-extension, SNP genotyping, solvent-tolerant, Thermostable
Category(s): Technology Classifications > Research Tools > Others