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Search Results - biomarkers
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Algorithm for Identifying Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more. Background: Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 4/1/2025
|
Inventor(s):
Alex Valm
,
Yunlong Feng
Keywords(s):
bacterial cells
,
bacterial infection
,
bioengineering
,
biofilm control
,
bioinformatics
,
biomarker diagnostics
,
biomarkers
,
cancer
,
cell biology
,
computational biology
,
dental
,
diagnostics
,
digital image processing
,
fluorescence
,
fluorescence spectroscopy
,
gene expression analysis
,
image analysis
,
image processing
,
machine learning
,
medical imaging
,
microbial pathogenesis
,
personalized medicine
,
RNA
,
saliva
,
scanning microscopy
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Biological Materials
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Healthcare
,
Technology Classifications > Medical Imaging
,
Technology Classifications > Research Tools and Reagents
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Viral Vectors
Stratification Method that Determines the Prognosis of Breast Cancer at a Personalized Level
A reliable, accurate, and versatile method for determining the prognosis of primary breast cancer tumors post-surgery. Background: Breast cancer is the second most common type of cancer in women in the United States, after skin cancer. On rare occasions, it can also occur in men. According to the American Cancer Society, nearly 300,000 new cases...
Published: 4/1/2025
|
Inventor(s):
Vladimir Kuznetsov
,
Leszek Kotula
Keywords(s):
biomarkers
,
biostatistics
,
breast cancer
,
diagnostics
,
functional genomics
,
gene expression analysis
,
oncology
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Diagnostics
,
Technology Classifications > Healthcare
,
Technology Classifications > Medical Devices
Novel FISH probes for the prognosis of malignant transformation in Barrett’s epithelium
Left: Translocations as visualized by FISH assay during metaphase. Right: Fusion as visualized in human esophageal adenocarcinoma tissue sectionInvention Summary:Barrett’s epithelium (BE) is a premalignant tissue that can progress into esophageal adenocarcinoma (EA) following the metaplasia→low grade dysplasia→ high grade dysplasia→cancer sequence....
Published: 2/12/2025
|
Inventor(s):
Kiron Das
,
Manisha Bajpai
,
Hana Aviv
Keywords(s):
Anti-cancer
,
Biomarkers
,
Cancer
biomarkers
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Diagnostics
,
Technology Classifications > Cancer
A Novel Lymphocyte Stimulation Assay To Quantify Immune Responses (UCLA Case No. 2022-079)
UCLA researchers in the Department of Medicine have developed lymphocyte stimulation assays to evaluate immune responses, supporting various clinical applications such as adjusting immunosuppressant drug levels and advancing COVID-19 vaccine development. The assay systems are reliable, cost-effective, and easy-to-perform, providing accurate assessments...
Published: 2/14/2025
|
Inventor(s):
Yusaku Shino
Keywords(s):
Antibody
,
biomarkers
,
cytokines
,
Immunity (Medical)
,
immunosuppression
,
Organ Transplant
Category(s):
Life Science Research Tools > Antibodies
,
Therapeutics > Immunology And Immunotherapy
Urine-Based Diagnostics for Prostate Cancer (UCLA Case No. 2023-302)
UCLA researchers in the Department of Human Genetics have developed a urine-based method for non-invasive prostate cancer diagnosis. By quantifying secreted and extracellular vesicles proteomes from urine, they identified protein
biomarkers
that enable accurate diagnosis and risk stratification of prostate cancer, outperforming the current PSA test. BACKGROUND:...
Published: 2/14/2025
|
Inventor(s):
Paul Boutros
Keywords(s):
biomarkers
,
Cancer
,
diagnostics
,
extracellular vesicle
,
genitourinary
,
prostate cancer
,
prostatic lesion
,
risk stratification
,
secreted proteome
,
urinary proteome
,
Urine-based
Category(s):
Diagnostic Markers
Salivary Exosome (NSEV) Analysis to Elucidate Intercellular Signaling Events that Precede Pilot Fatigue (UCLA Case No. 2021-172)
Researchers at UCLA’s Department of Neurology and Drug Discovery Lab have identified a novel set of
biomarkers
that change based on levels of Cognitive Fatigue (CF). These biomarkers can be used to non-invasively predict and assess levels of cognitive fatigue. BACKGROUND: Cognitive fatigue (CF) is an important factor in the efficiency and safety...
Published: 2/14/2025
|
Inventor(s):
Bruce Teter
,
Whitaker Cohn
,
Varghese John
Keywords(s):
biomarkers
,
cognitive fatigue
,
exosome
,
noninvasive
,
non-invasive
Category(s):
Diagnostic Markers > Targets And Assays
Bioinformatic Methods for Determining Resistance to Cancer Treatments
Invention Summary: Determining resistance to chemotherapy treatments for specific types of cancer (e.g., prostate, lung, breast, etc.,) as early as possible can prolong patients' lives by enabling them to be treated with other, and hopefully, more effective treatments as soon as possible. Researchers at Rutgers University have...
Published: 11/12/2024
|
Inventor(s):
Antonina Mitrofanova
,
Sukanya Panja
,
Sarki Abdulkadir
,
Vishal Kothari
,
Edward Schaeffer
Keywords(s):
Bioinformatics
,
Biomarkers
,
Digital Health
,
Prostate Cancer
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
,
Technology Classifications > Cancer
,
Technology Classifications > Healthcare & Life Sciences
STAR-Echo: Software to Predict Cardiovascular Disease in Chronic Kidney Disease Patients
Application A novel software for prognosis of MACE in chronic kidney disease patients using spatiotemporal analysis and transformer-based radiomics models. Key Benefits Unique interpretable features – identifies novel features based on longitudinal changes in LVW shape (perimeter & sphericity) and texture (intensity variations) over a...
Published: 2/13/2025
|
Inventor(s):
Rohan Dhamdhere
,
Sadeer Al-Kindi
,
Gourav Modanwal
,
Anant Madabhushi
Keywords(s):
Algorithm, AI, and Machine Learning
,
Biomarkers
,
Cardiovascular Treatments
,
Nephrology Treatments
Category(s):
TechPub Algolia > Software
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of
biomarkers
in bodily fluids....
Published: 2/14/2025
|
Inventor(s):
Aydogan Ozcan
,
Hyouarm Joung
,
Hyun-June Jang
,
Junhong Chen
Keywords(s):
Biomarker
,
biomarkers
,
Biomaterial
,
Biosensor
,
Computer-Aided Diagnosis
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Electrical
,
Electrical Engineering
,
electrically-mediated sensing
,
electrochemical sensors
,
enzyme functionalization
,
field-effect transistors (FETs)
,
Medical diagnostics
,
multiplexed analysis
,
Point Of Care
,
point-of-care
,
porous media
,
sample matrix effects
,
transistors
Category(s):
Electrical
,
Electrical > Sensors
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Platforms
,
Platforms > Diagnostic Platform Technologies
Novel diagnostic/prognostic
biomarkers
for multisystem inflammatory syndrome and SARS‐CoV‐2 infection
Schematic representation of how the proposed
biomarkers
can improve the diagnosis and treatment of MIS-C and COVID-19 Invention Summary: Disease prognosis of COVID-19 has largely been influenced by multiorgan involvement. Specifically, the multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for...
Published: 11/26/2024
|
Inventor(s):
Jeisac Guzmán Rivera
,
Maria Gennaro
,
Dirk Moore
Keywords(s):
Biomarkers
Category(s):
Technology Classifications > COVID-19
,
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Infectious Disease
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