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Search Results - hydrogel
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VOLUME IMAGING OF BIOLOGICAL SPECIMENS BY PHOTOCHEMICAL SECTIONING
VOLUME IMAGING OF BIOLOGICAL SPECIMENS BY PHOTOCHEMICAL SECTIONING Researchers at UC Berkeley and University of Illinois, Chicago have developed a nanoscale volume fluorescence imaging method that enables high-resolution imaging of large tissue volumes.
Hydrogel
-based tissue clearing and expansion techniques have improved the ability to study cellular...
Published: 11/6/2024
|
Inventor(s):
Gokul Upadhyayula
,
RuiXuan Gao
Keywords(s):
Hydrogel
,
Imaging
,
Photodegradable
Category(s):
Technology Classifications > Biology
A Novel “Host-Guest”-Based Supramolecular
Hydrogel
for Dental Pulp Regeneration (Case No. 2023-154)
Summary: Researchers in the Department of Dentistry at UCLA have developed an innovative
hydrogel
for a vast array of biomedical and tissue engineering applications. Background: Hydrogels have emerged as powerful tools in biomedical engineering due to their ability to provide a supportive environment for cell growth, tissue repair, and drug delivery....
Published: 10/14/2024
|
Inventor(s):
Alireza Moshaverinia
,
Weihao Yuan
Keywords(s):
anti-dehydration
,
Drug Delivery
,
dynamic identification
,
hydrogel
,
Stem Cells / Regenerative Medicine
,
Targeted Therapy
,
tissue regeneration
Category(s):
Chemical
,
Materials > Functional Materials
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Antibody Delivery Platforms
,
Platforms > Drug Delivery > Nanoparticles
,
Platforms > Drug Delivery > Viral Delivery Systems
,
Therapeutics > Cell Therapy
,
Therapeutics > Medication
,
Therapeutics > Stem Cells And Regenerative Medicine
COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Charles Chan
,
Thomas Ambrosi
,
Irving Weissman
,
Michael Longaker
,
Rahul Sinha
,
Debashis Sahoo
Keywords(s):
Hydrogel
,
Stem Cell
Category(s):
Technology Classifications > Biology
Aesthetics and Wound Healing-related Technologies
NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-071; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094 Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes
hydrogel
s...
Published: 12/19/2024
|
Inventor(s):
Keywords(s):
Adhesive
,
Biomedical
,
Biotechnology
,
General surgery
,
Hydrogel
,
Wound Healing
Category(s):
Life Sciences > Therapeutics
,
Life Sciences > Healthcare Devices, Tools & IT
Functional Enrichment and Purification of a Therapeutically Superior Population of Cells (Case No. 2024-024)
Summary: UCLA researchers in the Departments of Bioengineering and Biological Chemistry have developed a method for identifying and enriching therapeutically useful cell sub-populations based on their secretions (SEC-seq). Background: Cell function is defined by a myriad of biomolecules that they secrete; over 3 thousand proteins are estimated to...
Published: 9/11/2024
|
Inventor(s):
Dino Di Carlo
,
Kathrin Plath
,
Shreya Udani
,
Justin Langerman
Keywords(s):
Cell Surface Receptor
,
Cytometry
,
Flow Cytometry
,
Functional Genomics
,
High-Throughput Screening
,
hydrogel
,
Microfluidics
,
single cell analysis
,
Therapeutics
Category(s):
Therapeutics > Immunology And Immunotherapy
,
Therapeutics
,
Therapeutics > Oncology > Oncology Immunotherapy
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Diagnostic Markers > Targets And Assays
,
Therapeutics > Cell Therapy
Affinity and Functional Based Screening of T Cell Receptor Repertoire Using Nanovials (Case No. 2024-042)
Summary: Researchers in the Department of Bioengineering at UCLA have developed a
hydrogel
platform that measures single T cell secretions, aiding in the definition of T cell receptor repertoires for functional immunotherapy applications. Background: T cell immunotherapies, namely T cell receptor (TCR) therapies, have emerged as promising candidates...
Published: 10/8/2024
|
Inventor(s):
Dino Di Carlo
,
Owen Witte
,
Doyeon Koo
,
Zhiyuan Mao
Keywords(s):
Cancer Immunotherapy
,
CAR-T cell therapy
,
Flow Cytometry
,
hydrogel
,
Immunooncology
,
Immunotherapy
,
Peptide
,
single cell analysis
,
T Cell
,
T cell based therapy
Category(s):
Diagnostic Markers > Immunology
,
Life Science Research Tools > Screening Libraries
,
Therapeutics > Immunology And Immunotherapy
HYDROGEL
PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING
HYDROGEL
PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING Researchers at the NIH and UCSF have developed methods that detect RNA or DNA markers with single molecule sensitivity in cells of interest that allow rapid isolation of these cells or extracts/derivatives of these cells for in-depth transcriptomic, genomic or epigenomic analyses....
Published: 10/26/2023
|
Inventor(s):
Adam Abate
,
Iain Clark
,
Eli Boritz
Keywords(s):
High-Throughput
,
Hydrogel
,
Microfluidic
,
Single Cell Genomics
,
Single Cell Transcriptomics
Category(s):
Technology Classifications > Biology
A peptide
hydrogel
for use in vascular anastomosis
Abstract: In collaboration with surgery specialists from Johns Hopkins University, researchers at the National Cancer Institute (NCI) developed novel
hydrogel
compositions and methods of using them in the microsurgical suturing of blood vessels, which is particularly beneficial for surgeons in whole tissue transplant procedures. The lead candidate electropositive...
Published: 12/6/2024
|
Inventor(s):
Joel Schneider
,
Gerald Brandacher
,
Daniel Smith
,
Gabriel Brat
,
Johanna Grahammer
Keywords(s):
Anastomosis
,
Hydrogel
,
Microsurgery
,
Peptide
,
Schneider
,
Surgery
Category(s):
TherapeuticArea > Oncology
,
TherapeuticArea > Endocrinology
,
Application > Non-Medical Devices
,
TherapeuticArea > Reproductive Health
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Infectious Disease
,
Collaboration Sought > Licensing
,
Application > Medical Devices
,
TherapeuticArea > Dermatology
,
TherapeuticArea > Immunology
,
TherapeuticArea > Gastroenterology
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Nephrology
,
TherapeuticArea > Ear, Nose, & Throat
,
TherapeuticArea > Ophthalmology
Nanoparticle-
hydrogel
Composite for Nucleic Acid Molecule Delivery
Abstract: Mesothelioma is an aggressive cancer covering anatomic surfaces (e.g. lining of the lungs, heart, abdomen, etc.) that resists multi-modality therapies. Regional recurrence of mesothelioma from residual tumor cells prevents long-term benefits after surgical resection. Furthermore, there is no clinical consensus on intracavitary adjuvants that...
Published: 4/8/2024
|
Inventor(s):
Joel Schneider
,
Poulami Majumder
,
Chuong Hoang
,
Anand Singh
Keywords(s):
Hoang
,
Hydrogel
,
Mesothelioma
,
MicroRNA
,
Nanoparticle
,
Schneider
,
Surface Cancer
Category(s):
TherapeuticArea > Oncology
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Therapeutics
SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED
HYDROGEL
S
SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED
HYDROGEL
S Researchers at UCSF have developed materials and methods for high throughput single cell epigenomic sequencing using a capture/profiling approach with hydrogel scaffolds, thus facilitating a scale and form of epigenomic profiling beyond what has been previously...
Published: 7/6/2023
|
Inventor(s):
Adam Abate
,
Xiangpeng Li
Keywords(s):
DNA Capture
,
Droplet
,
Epigenomic
,
High-Throughput
,
Hydrogel
,
Microfluidic
,
Single-Cell
Category(s):
Technology Classifications > Biology
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