Search Results - hydrogel

13 Results

Sort By:

COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS

COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...

Published: 9/24/2024 | Inventor(s): Charles Chan, Thomas Ambrosi, Irving Weissman, Michael Longaker, Rahul Sinha, Debashis Sahoo

Keywords(s): Hydrogel, Stem Cell

Category(s): Technology Classifications > Biology

Aesthetics and Wound Healing-related Technologies

NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-071; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094 Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes hydrogels...

Published: 9/10/2024 | Inventor(s):

Keywords(s): Adhesive, Biomedical, Biotechnology, General surgery, Hydrogel, Wound Healing

Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT

Functional Enrichment and Purification of a Therapeutically Superior Population of Cells (Case No. 2024-024)

Summary: UCLA researchers in the Departments of Bioengineering and Biological Chemistry have developed a method for identifying and enriching therapeutically useful cell sub-populations based on their secretions (SEC-seq). Background: Cell function is defined by a myriad of biomolecules that they secrete; over 3 thousand proteins are estimated to...

Published: 9/11/2024 | Inventor(s): Dino Di Carlo, Kathrin Plath, Shreya Udani, Justin Langerman

Keywords(s): Cell Surface Receptor, Cytometry, Flow Cytometry, Functional Genomics, High-Throughput Screening, hydrogel, Microfluidics, single cell analysis, Therapeutics

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Therapeutics > Cell Therapy

Affinity and Functional Based Screening of T Cell Receptor Repertoire Using Nanovials (Case No. 2024-042)

Summary: Researchers in the Department of Bioengineering at UCLA have developed a hydrogel platform that measures single T cell secretions, aiding in the definition of T cell receptor repertoires for functional immunotherapy applications. Background: T cell immunotherapies, namely T cell receptor (TCR) therapies, have emerged as promising candidates...

Published: 9/20/2024 | Inventor(s): Dino Di Carlo, Owen Witte, Doyeon Koo, Zhiyuan Mao

Keywords(s): Cancer Immunotherapy, CAR-T cell therapy, Flow Cytometry, hydrogel, Immunooncology, Immunotherapy, Peptide, single cell analysis, T Cell, T cell based therapy

Category(s): Diagnostic Markers > Immunology, Life Science Research Tools > Screening Libraries, Therapeutics > Immunology And Immunotherapy

HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING

HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING Researchers at the NIH and UCSF have developed methods that detect RNA or DNA markers with single molecule sensitivity in cells of interest that allow rapid isolation of these cells or extracts/derivatives of these cells for in-depth transcriptomic, genomic or epigenomic analyses....

Published: 10/26/2023 | Inventor(s): Adam Abate, Iain Clark, Eli Boritz

Keywords(s): High-Throughput, Hydrogel, Microfluidic, Single Cell Genomics, Single Cell Transcriptomics

Category(s): Technology Classifications > Biology

A peptide hydrogel for use in vascular anastomosis

Abstract: In collaboration with surgery specialists from Johns Hopkins University, researchers at the National Cancer Institute (NCI) developed novel hydrogel compositions and methods of using them in the microsurgical suturing of blood vessels, which is particularly beneficial for surgeons in whole tissue transplant procedures. The lead candidate electropositive...

Published: 4/8/2024 | Inventor(s): Joel Schneider, Gerald Brandacher, Daniel Smith, Gabriel Brat, Johanna Grahammer

Keywords(s): Anastomosis, Hydrogel, Microsurgery, Peptide, Schneider, Surgery

Nanoparticle-hydrogel Composite for Nucleic Acid Molecule Delivery

Abstract: Mesothelioma is an aggressive cancer covering anatomic surfaces (e.g. lining of the lungs, heart, abdomen, etc.) that resists multi-modality therapies. Regional recurrence of mesothelioma from residual tumor cells prevents long-term benefits after surgical resection. Furthermore, there is no clinical consensus on intracavitary adjuvants that...

Published: 4/8/2024 | Inventor(s): Joel Schneider, Poulami Majumder, Chuong Hoang, Anand Singh

Keywords(s): Hoang, Hydrogel, Mesothelioma, MicroRNA, Nanoparticle, Schneider, Surface Cancer

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics

SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS

SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS Researchers at UCSF have developed materials and methods for high throughput single cell epigenomic sequencing using a capture/profiling approach with hydrogel scaffolds, thus facilitating a scale and form of epigenomic profiling beyond what has been previously...

Published: 7/6/2023 | Inventor(s): Adam Abate, Xiangpeng Li

Keywords(s): DNA Capture, Droplet, Epigenomic, High-Throughput, Hydrogel, Microfluidic, Single-Cell

Category(s): Technology Classifications > Biology

PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING

PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING Researchers at UCSF have developed a method for high throughput single-cell multi-omic sequencing that is rapid, simple to operate, and offers key innovations over existing technologies. Single-cell sequencing technologies refer to the methods to obtain genomics, transcriptomics or multi-omics...

Published: 4/20/2023 | Inventor(s): Adam Abate, Xiangpeng Li, Benjamin Demaree

Keywords(s): Genomic DNA, Hydrogel, Microfluidic, Partitioning, Sequencing, Single-Cell, Transcriptomics

Category(s): Technology Classifications > Biology

2020-747 Multi-Functional Anti-Icing Hydrogel Technique for Controlling Ice Nucleation, Growth, and Adhesion

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed an anti-icing coating that is the first to incorporate a trifold approach by lowering the ice formation temperature, making the surface difficult for ice to stick to and delaying ice crystal growth. Background: Undesired icing/frosting on various surfaces...

Published: 9/26/2023 | Inventor(s): Ximin He

Keywords(s): adhesion, anti-freeze, anti-icing, ceramic, Ceramics, Coating, Coatings, Adhesives, & Inks, General Device Coatings, glass, hydrogel, ice, ice prevention, mechanical durability, nucleation, organo hydrogel, spin coat, temperature control

Category(s): Chemical > Coatings, Adhesives & Inks, Materials > Membranes, Chemical > Polymers, Energy & Environment > Thermal

1 2