Search Results - mouse+models

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Genetically Encoded Membrane Tension Sensor for Real-Time Fluorescent Imaging
This technology is a genetically encoded, membrane-bound fluorescent tension sensor that converts changes in cell membrane tension into changes in light intensity. It enables real-time visualization and measurement of mechanical forces in living cells, tissues, and model systems for mechanobiology research, disease modeling, and therapeutic screening. The...
Published: 5/15/2026   |   Updated: 5/15/2026   |   Inventor(s): Em Ben Sorum
Keywords(s): Cell Lines, Drug Screening, Fluorescence, Imaging, Membranes, Mouse Models, Quantification
Category(s): Research Tools, Human Health Care, Human Health Care > Biomarkers, Diagnosis and Detection
Murine metastatic pancreatic adenocarcinoma cell lines
Abstract: Researchers at the National Cancer Institute (NCI) have developed orthotopic allograft models for pancreatic cancer that utilize low passage primary pancreatic adenocarcinoma cells or tumor fragments implanted into the cancer-free pancreata of recipient syngeneic immunocompetent mice. Tumor development in these models is more synchronized,...
Published: 5/29/2025   |   Updated: 8/2/2023   |   Inventor(s): Serguei Kozlov, Ludmila Szabova, Melanie Gordon, Myhaymin Kamal, Jerome Schlomer, Theresa Guerin, Theresa O'Sullivan, Terry Van Dyke
Keywords(s): ADENOCARCINOMA, CANCER, GEM-Derived Allograft, Inflammation, Kozlov, Mouse Models, Pancreatic
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials