Search Results - reza+nazari

3 Results Sort By:
Modular 3D Printed Devices for Sample Delivery
­Background Microfluidic devices are commonly used in serial crystallography applications. In most serial crystallography experiments, the sample molecules are formed into droplets through electrical stimulation, then injected into a focused beam of electrons or X-rays so their structure can be analyzed. The various components of the experiment...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, John Spence, Diandra Doppler, Garrett Nelson, Richard Kirian, Reza Nazari, Ana Egatz-Gomez, Mukul Sonker, Mohammad Rabbani
Keywords(s):  
Category(s): Physical Science, Bioanalytical Assays, Chemistries & Devices
3D-Printed Microfluidic Device Featuring Electronically Triggered Droplet Generation and Injection for Serial Crystallography
Background Serial femtosecond crystallography (SFX) with recent advances in X-ray free electron lasers (XFELs) is a revolutionary technique for determining the structure of macromolecules at ambient temperature. It has enabled the study of large membrane protein complexes at atomic resolution and their reaction dynamics, previously considered impossible...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, Daihyun Kim, Diandra Doppler, Jorvani Cruz Villarreal, Richard Kirian, Reza Nazari, Sahir Gandhi
Keywords(s):  
Category(s): Chemical/Biological Sensors, Bioanalytical Assays, Chemistries & Devices, Physical Science, Manufacturing/Construction/Mechanical
Co-Flow Injection for Serial Crystallography Using a 3D-Printed Hybrid Nozzle/T-Junction Device
Background Serial femtosecond crystallography (SFX) with X-ray free electron lasers (XFELs) has enabled crystal structure determination of reaction intermediates at ambient temperatures. Unlike traditional crystallography, where a single crystal is irradiated as it rotates, SFX usually involves the injection of a continuous stream of randomly oriented...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, Daihyun Kim, Austin Echelmeier, Jorvani Cruz Villarreal, Diandra Doppler, Richard Kirian, Reza Nazari
Keywords(s):  
Category(s): Physical Science, Bioanalytical Assays, Chemistries & Devices, Manufacturing/Construction/Mechanical, Chemical/Biological Sensors