Search Results - research+tools

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Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics
­PRODUCT OPPORTUNITIES Cell-membrane-coated, cargo-encapsulated polymer nanoparticles as target-specific prodrugs PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Enhanced cellular uptake and endosomal escape, resulting in more efficient delivery of therapeutics Enhanced selectivity of intracellular delivery of therapeutics TECHNOLOGY...
Published: 3/9/2026   |   Updated: 3/9/2026   |   Inventor(s): Sankaran Thayumanavan
Keywords(s):  
Category(s): Healthcare, Life Sciences, Biotechnology, Nanotechnology, Therapeutics & prevention, Research tools
Malassezia-Secreted Factor with Antibiotic Activity
1. Technology Overview The invention introduces a novel antimicrobial activity produced by human-associated fungi, specifically Malassezia sympodialis, for potential development as antibiotics. The secreted factor exhibits bactericidal activity against Staphylococcus aureus and enhances bacterial sensitivity to other antibiotics, making it suitable...
Published: 1/8/2026   |   Updated: 1/2/2026   |   Inventor(s): Matthew Barber, Caitlin Kowalski
Keywords(s):  
Category(s): Therapeutics, Diagnostics, Research Tools
Novel Curcumin Derivatives with Enhanced Anti-Inflammatory Properties
SUMMARY This technology comprises two novel curcumin derivatives - compounds D3 and D4 - with potent anti-inflammatory properties. These compounds effectively inhibit a key inflammatory signaling pathway, offering enhanced therapeutic potential over traditional curcumin. The technology provides improved bioactive compounds for nutraceutical and pharmaceutical...
Published: 12/9/2025   |   Updated: 12/9/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Natural Products, Research Tools, Therapeutics
Genetic engineering approach for enhancing recombinant protein production by mammalian cells
Summary Vanderbilt researchers have developed a novel approach to enhance recombinant protein production in mammalian cell culture systems through metabolic engineering. By overexpressing specific metabolic proteins in these cells, this technology achieves higher monoclonal antibody titers and increased cell-specific productivity compared to conventional...
Published: 12/9/2025   |   Updated: 12/2/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Biomanufacturing, Research Tools, Therapeutics
Oxygen-Tolerant Probiotic Therapy for Intestinal Inflammatory Diseases
Summary Anaerobic bacteria used in current probiotic compositions cannot tolerate the oxygen stress found in the gut during inflammation, reducing their effectiveness in restoring a healthy gut microbiome. Vanderbilt researchers have engineered Bacteroides thetaiotaomicron, an obligate anaerobe, to endure oxygen-rich conditions in the gut. This advancement...
Published: 12/2/2025   |   Updated: 12/2/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Research Tools, Therapeutics
Real-Time High-Resolution Eye-Tracking
Real-Time High-Resolution Eye-Tracking High-precision eye-tracking system using Purkinje reflections for real-time gaze localization in virtual and augmented reality applications Institute Reference: 1-18137 Background Eye-tracking systems are widely used in fields like clinical diagnostics, human-computer interaction, and virtual/augmented reality....
Published: 11/19/2025   |   Updated: 11/19/2025   |   Inventor(s): Michele Rucci, Ruei-Jr Wu, Zhetuo Zhao
Keywords(s):  
Category(s): Devices, Optics, Research Tools
Vinyl-Comonomer Additive for Radically Activated Dynamic Phenomena
­PRODUCT OPPORTUNITIES •Recycling vinyl-derived polymers • Sustainable plastics •Upcycled waste materials PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES • Broad material compatibility • Complete radical closed-loop cycling • Upcycle capability TECHNOLOGY DESCRIPTION This invention demonstrates...
Published: 11/6/2025   |   Updated: 11/6/2025   |   Inventor(s): Reika Katsumata, Autumn Mineo
Keywords(s):  
Category(s): Chemicals, Engineering, Material science, Physical Science, Research tools
Demineralized Bone Paper and Applications Thereof
PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...
Published: 12/19/2025   |   Updated: 10/1/2025   |   Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak
Keywords(s):  
Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...
Published: 9/25/2025   |   Updated: 9/25/2025   |   Inventor(s): Lisa Minter, Gregory Tew, Emrah Ozay
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
The Floor Projection Maze: A novel rodent model system for studying how complex visual information guides behavior and cognition.
Floor Projection Maze: A Novel Rodent Model System for Studying Visual Cognition Overview The Floor Projection Maze stands as an innovative rodent research platform, specifically designed to advance our understanding of visual information processing, learning, memory, and attention. This device projects two-dimensional visual cues onto the maze floor...
Published: 10/29/2025   |   Updated: 8/13/2025   |   Inventor(s): Rebecca Burwell
Keywords(s):  
Category(s): Research Tools
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