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Genetically Modified Cell Line for Enhanced Viral Vector Manufacturing

Summary Recent FDA approvals have spurred the demand for viral vector products, prompting the need for more efficient bioproduction methods. In this context, Vanderbilt researchers have engineered a new cell line with significantly enhanced viral production capabilities compared to traditional cell lines. This innovation is expected to lead to substantial...

Published: 8/27/2024 | Inventor(s):

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Category(s): Research Tools, Natural Products

A novel, modular, apparatus to measure rodent spatial and social cognition without the limitations of currently used apparatuses

Overview The ability to understand, create and maintain social relationships is a fundamental part of life. Emerging research shows there is a critical link between the social networks we create and our spatial cognition. For example, social relationships are often described in terms of space, varying from “close” to “distant.”...

Published: 8/12/2024 | Inventor(s): Taylor Wise, Rebecca Burwell

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Category(s): Research Tools

Pediatric Cardiac Defect Heart Model

Reference #: 1716 The University of South Carolina is offering licensing opportunities for Pediatric Cardiac Defect Heart Model. Background: To address the current nursing shortage, it is critical to get qualified and well-trained nurses into the profession as quickly as possible without sacrificing quality training. Manipulative anatomy tools are...

Published: 9/16/2024 | Inventor(s): Stephanie Schaller, Katherine Chappell, Lonnie Rosier, Teresa Bowers

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Category(s): Research Tools, Health Sciences

Fluidic control system for repeat analysis of individual particles

Reference #: 1709 The University of South Carolina is offering licensing opportunities for Fluidic Control System for Repeat Analysis of Individual Particles Background: Cytometry is the study of cellular/particle characteristics in a controlled environment by subjecting them to multiple tests/treatments in order to classify and distinguish them....

Published: 7/29/2024 | Inventor(s): Michael Myrick, Zechariah Kitzhaber

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Category(s): Chemistry and Biochemistry, Research Tools

Denoising Algorithm for Sets of Evoked Potentials

Denoising Algorithm for Sets of Evoked Potentials A mathematical algorithm that denoises separately measured evoked potentials. Institute Reference: 2-23107 Background Evoked potentials are measured brain responses to some stimulus typically measured on the scalp using electroencephalography (EEG) electrodes. Measuring evoked potential serves many...

Published: 7/22/2024 | Inventor(s): Ross Maddox

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Category(s): Research Tools, Diagnostic

In-Situ Beta-particle detector for High Resolution 234Th Export Measurements

Reference #: 01654 The University of South Carolina is offering licensing opportunities for In-Situ Beta-particle Detector for High Resolution 234Th Export Measurements. Background: Thorium-234 (234Th) levels serve as a crucial indicator of carbon sequestration from the ocean surface. Measuring 234Th activity in ocean-settling particles can be used...

Published: 7/15/2024 | Inventor(s): Tim Shaw, Michael Myrick

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Category(s): Research Tools, Environmental and Sustainability

Precision Diagnostics: COVID-19 Severity Assessment via Advanced Plasma Biomarkers

24023-05: Precision Diagnostics: COVID-19 Severity Assessment via Advanced Plasma Biomarkers Inventor: Marko Radic, Ph.D. •COVID-19 patients who died had extensive damage to the elastin fibers in the lungs. •This suggests that neutrophil activity and elastin degradation play a crucial role in pulmonary fibrosis development. •High...

Published: 5/2/2024 | Inventor(s): Marko Radic

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Category(s): Research Tools

Magnetohydrodynamic clearing and antibody staining

PRODUCT OPPORTUNITIES Devices and methods for moving charged molecules into and out of tissue samples PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Significantly reduces the time required to clear tissue samples Significantly reduces the time required for histological procedures in large tissue samples Removes biomarkers...

Published: 5/3/2024 | Inventor(s): Joseph Bergan, Joseph Dwyer

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Category(s): Biotechnology, Devices, Life Sciences, Research tools

Let-7 promotes superior anti-tumor activity of CD8 T cells and memory formation

PRODUCT OPPORTUNITIES Improve T-cell therapies PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Improve cancer immunotherapies that are based on adoptive T cell transfer/ improves T-cell therapies TECHNOLOGY DESCRIPTION This invention demonstrates that let-7 miRNA regulates T cell responses...

Published: 4/29/2024 | Inventor(s): Leonid Pobezinsky, Elena Pobezinskaya

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Category(s): Biotechnology, Life Sciences, Therapeutics & prevention, Research tools

Accurate Tracking and Measurement of Intercellular Mitochondrial Transfer

Opportunity Mitochondria are commonly referred to as the powerhouse of the cell, and any change in mitochondrial function can drastically alter normal cell function. Diseases including neurodegeneration and cancer have been linked to changes in mitochondrial transfer between cells, which can weaken the functioning of healthy cells. Although studying...

Published: 3/14/2024 | Inventor(s): Simon Grelet, Greg Hoover

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Category(s): All Technologies, Cancer Therapeutics, Research Tools, Screening Tests

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