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Search Results - research+tools
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Genetic engineering approach for enhancing recombinant protein production by mammalian cells
Summary Vanderbilt researchers have developed a novel approach to enhance recombinant protein production in mammalian cell culture systems through metabolic engineering. By overexpressing specific metabolic proteins in these cells, this technology achieves higher monoclonal antibody titers and increased cell-specific productivity compared to conventional...
Published: 12/2/2025
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Inventor(s):
Keywords(s):
Category(s):
Biomanufacturing
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Research Tools
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Therapeutics
Oxygen-Tolerant Probiotic Therapy for Intestinal Inflammatory Diseases
Summary Anaerobic bacteria used in current probiotic compositions cannot tolerate the oxygen stress found in the gut during inflammation, reducing their effectiveness in restoring a healthy gut microbiome. Vanderbilt researchers have engineered Bacteroides thetaiotaomicron, an obligate anaerobe, to endure oxygen-rich conditions in the gut. This advancement...
Published: 12/2/2025
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Inventor(s):
Keywords(s):
Category(s):
Research Tools
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Therapeutics
Real-Time High-Resolution Eye-Tracking
Real-Time High-Resolution Eye-Tracking High-precision eye-tracking system using Purkinje reflections for real-time gaze localization in virtual and augmented reality applications Institute Reference: 1-18137 Background Eye-tracking systems are widely used in fields like clinical diagnostics, human-computer interaction, and virtual/augmented reality....
Published: 11/19/2025
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Inventor(s):
Michele Rucci
,
Ruei-Jr Wu
,
Zhetuo Zhao
Keywords(s):
Category(s):
Devices
,
Optics
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Research Tools
Vinyl-Comonomer Additive for Radically Activated Dynamic Phenomena
PRODUCT OPPORTUNITIES •Recycling vinyl-derived polymers • Sustainable plastics •Upcycled waste materials PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES • Broad material compatibility • Complete radical closed-loop cycling • Upcycle capability TECHNOLOGY DESCRIPTION This invention demonstrates...
Published: 11/6/2025
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Inventor(s):
Reika Katsumata
,
Autumn Mineo
Keywords(s):
Category(s):
Chemicals
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Engineering
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Material science
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Physical Science
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Research tools
Demineralized Bone Paper and Applications Thereof
PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...
Published: 10/1/2025
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Inventor(s):
Jungwoo Lee
,
Jae-Hyuck Shim
,
Ryan Carpenter
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Yongkuk Park
,
Jun-Goo Kwak
Keywords(s):
Category(s):
Biotechnology
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Devices
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Healthcare
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Life Sciences
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Research tools
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Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...
Published: 9/25/2025
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Inventor(s):
Lisa Minter
,
Gregory Tew
,
Emrah Ozay
Keywords(s):
Category(s):
Biotechnology
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Healthcare
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Life Sciences
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Research tools
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Therapeutics & prevention
The Floor Projection Maze: A novel rodent model system for studying how complex visual information guides behavior and cognition.
Floor Projection Maze: A Novel Rodent Model System for Studying Visual Cognition Overview The Floor Projection Maze stands as an innovative rodent research platform, specifically designed to advance our understanding of visual information processing, learning, memory, and attention. This device projects two-dimensional visual cues onto the maze floor...
Published: 10/29/2025
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Inventor(s):
Rebecca Burwell
Keywords(s):
Category(s):
Research Tools
Pediatric Cardiac Defect Heart Model
Reference #: 1716 The University of South Carolina is offering licensing opportunities for Pediatric Cardiac Defect Heart Model. Background: To address the current nursing shortage, it is critical to get qualified and well-trained nurses into the profession as quickly as possible without sacrificing quality training. Manipulative anatomy tools are...
Published: 10/30/2025
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Inventor(s):
Stephanie Schaller
,
Katherine Chappell
,
Lonnie Rosier
,
Teresa Bowers
Keywords(s):
Category(s):
Research Tools
,
Health Sciences
The Myotonic Dystrophy Type-1 Health Index (MDHI Type-1) Italian Translation
The Myotonic Dystrophy Health Index (MDHI) Italian Version is a survey designed to efficiently measure the overall level of disease burden in a patient with myotonic dystrophy type-1 whose native language is Italian. This disease-specific patient-reported outcome measure is designed is designed to reliably and responsively measure therapeutic benefit...
Published: 12/16/2024
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Inventor(s):
Chad Heatwole
Keywords(s):
Category(s):
Copyright
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Informatics
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Research Tools
Quantifying Cell-Derived Changes in Collagen Synthesis, Alignment, and Mechanics in a 3D Connective Tissue Model
Quantifying Cell-Derived Changes in Collagen Synthesis, Alignment, and Mechanics in a 3D Connective Tissue Model Overview The extracellular matrix (ECM) of the body is the network of proteins and other molecules that surrounds cells and tissues. The ECM is directly involved in a variety of essential cellular processes including structural support,...
Published: 10/31/2025
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Inventor(s):
Jeffrey Morgan
,
Benjamin Wilks
Keywords(s):
Category(s):
Stem Cells and Regenerative Medicine
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Research Tools
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Drug Discovery Platform
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