Search Results - antibody

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COMPOSITIONS AND METHODS RELATED TO CORONAVIRUS THERAPIES
COMPOSITIONS AND METHODS RELATED TO CORONAVIRUS THERAPIES Researchers at Stanford have developed fusion proteins, containing ACE2 domain linked to a fragment of non-neutralizing anti-SARS-CoV-2 spike protein antibody, with a greater breadth of protection than previously described similar fusion proteins. Coronaviruses are a large family of viruses...
Published: 11/6/2024   |   Inventor(s): Peter Kim, Adrian Hugenmatter, Ashley Utz, Matthew Armbrust
Keywords(s): ACE2, Antibody, Coronavirus, Neutralizing, Spike
Category(s): Technology Classifications > Biology
Anti-Green Fluorescent Protein Antibodies
Applications Western Blot Immunocytochemistry Immunohistochemistry Specificity Vertebrates Subtype Chicken Polyclonal Immunogen His-tagged green fluorescent protein of the bioluminescent hydrozoan jellyfish (Aequorea Victoria). Technical Summary Drs. Tomasiewicz, Wood, & Flaherty have created a polyclonal anti- green fluorescent...
Published: 9/26/2024   |   Inventor(s): Henry Tomasiewicz, John Wood, Denise Flaherty
Keywords(s): Antibody
Category(s): TechPub Algolia > Research Tools
­METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES
­METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES Researchers at Stanford have developed new methods to create programmable synthetic receptors (PAGER). The advent of programmable synthetic receptors represents a new era in cellular therapies and in biomedical science. There are currently tens...
Published: 12/5/2023   |   Inventor(s): Nicholas Kalogriopoulos, Alice Ting, Matthew Ravalin, Reika Tei
Keywords(s): Antibody, Fusion Protein, Receptor
Category(s): Technology Classifications > Biology
­ANTIBODY COMPOSITIONS AND OPTIMIZATION METHODS
­ANTIBODY COMPOSITIONS AND OPTIMIZATION METHODS Researchers at Stanford have invented a method using directed evolution for predicting antibody improved antibody variants. Evolution searches across an immense space of possible sequences for rare mutations that improve fitness. In nature, this search is based on random mutation and recombination,...
Published: 9/14/2023   |   Inventor(s): Brian Hie, Peter Kim
Keywords(s): Antibody, Variant
Category(s): Technology Classifications > Software
ANTIBODIES TO IL1RN AS MARKERS OF PRETERM BIRTH
ANTIBODIES TO IL1RN AS MARKERS OF PRETERM BIRTH Researchers at CZ Biohub SF and UCSF have discovered a novel biomarker of pre-term birth. Little is known about pre-term delivery risk and more specifically the immunological processes that allow for tolerance of a semi-allogenic fetus within the mother’s body. However, the processes that govern...
Published: 8/17/2023   |   Inventor(s): Elze Rackaityte, Joseph DeRisi
Keywords(s): Antibody, Biomarker, Preterm Delivery Risk
Category(s): Technology Classifications > Biology
High-Affinity Mouse Monoclonal Antibodies to GPC-3 for Liver Cancer Research
Abstract: The National Cancer Institute Laboratory of Molecular Biology seeks parties for collaborative research to co-develop and commercialize antibody drug/toxin conjugates as liver cancer therapy and diagnostics.  There is great interest and value in developing more sensitive and efficient agents for earlier detection of hepatocellular cancer (HCC). ...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Yen Phung, Wei Gao, Yifan Zhang
Keywords(s): ANTIBODY, GLYCOPROTEIN, Glypican-3, GPC3, HCC, hepatocellular carcinoma, liver, monoclonal
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing
Anti-Py1235-Met Immunological Binding Reagent as Cancer Diagnostic
Abstract: This technology consists of highly specific rabbit monoclonal antibodies reactive with phosphorylated tyrosine located at amino acid 1235 in the human MET sequence. Binding to this pYl235 residue is independent of the phosphorylation of other tyrosines in the vicinity (1230 and 1234), does not cross-react with these nearby phosphotyrosine...
Published: 4/8/2024   |   Inventor(s): Apurva Srivastava, Thomas Pfister, Mario Navas, James Doroshow, Ralph Parchment
Keywords(s): ANTIBODY, Companion Diagnostic, diagnostic, MET, Rabbit Monoclonal Antibody, tyrosine kinase inhibitor
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology
Antibody and Immunotoxin Treatments for Mesothelin-expressing Cancers
Abstract: Mesothelin is a cell surface protein that is highly expressed in aggressive cancers such as malignant mesothelioma, ovarian cancer, pancreatic cancer, lung cancer, breast cancer, cholangiocarcinoma, bile duct carcinoma and gastric cancer. As a result, mesothelin is an excellent candidate for tumor targeted immunotherapeutics. However, the...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Ira Pastan
Keywords(s): ANTIBODY, Immunotherapy, MESOTHELIN, therapeutic
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology
Human Antibodies Against Middle East Respiratory Syndrome Coronavirus
Abstract: No effective therapeutics or vaccines against Middle East Respiratory Syndrome Coronavirus (MERS-CoV) are available. The human-to-human aspect of transmission and the high mortality rate associated with MERS-CoV infection have raised concerns over the potential for a future MERS-CoV pandemic and emphasized the need for development of effective...
Published: 5/22/2024   |   Inventor(s): Dimiter Dimitrov, Tianlei Ying, Tina Ju, Kwok Yuen
Keywords(s): ANTIBODY, CORONAVIRUS, MERs, middle east respiratory syndrome
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Infectious Disease
Monoclonal Antibodies and Immunoconjugates Directed to the Non-ShedPortion (“Stalk”) of Mesothelin are Excellent Candidates for Developing Therapeutic Agents
Abstract: Human mesothelin is overexpressed by various cancers such as synovial sarcoma, mesothelioma, and ovarian, lung, esophageal, and gastric cancers. This selective expression on certain cancers suggests that mesothelin is an excellent target for anticancer therapeutics. However, a large fragment (“the shed portion”) of mesothelin is constantly...
Published: 5/21/2024   |   Inventor(s): Ira Pastan, Masanori Onda, Tapan Bera, Mitchell Ho
Keywords(s): ANTIBODY, CANCER, CAR, chimeric antigen receptor, diagnostic, IMMUNOCONJUGATES, IMMUNOTOXINS, MESOTHELIN, Pastan, therapeutic
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
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