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Search Results - diagnostics
153
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ID
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Urine-Based
Diagnostics
for Prostate Cancer (UCLA Case No. 2023-302)
UCLA researchers in the Department of Human Genetics have developed a urine-based method for non-invasive prostate cancer diagnosis. By quantifying secreted and extracellular vesicles proteomes from urine, they identified protein biomarkers that enable accurate diagnosis and risk stratification of prostate cancer, outperforming the current PSA test. BACKGROUND:...
Published: 11/5/2024
|
Inventor(s):
Paul Boutros
Keywords(s):
biomarkers
,
Cancer
,
diagnostics
,
extracellular vesicle
,
genitourinary
,
prostate cancer
,
prostatic lesion
,
risk stratification
,
secreted proteome
,
urinary proteome
,
Urine-based
Category(s):
Diagnostic Markers
Fast, Low-Input, Easy and Affordable Chromatin ImmunoPrecipitation (FLEA-ChIP)
FLEA-ChIP (Fast, Low-input, Easy and Affordable Chromatin ImmunoPrecipitation) is an efficient, reproducible, and sensitive method for ultra-low input epigenetic profiling, scalable to single cell resolution. FLEA-ChIP has been specifically designed to identify protein-DNA (histone marks and transcription factors) interactions from limiting and degraded...
Published: 10/4/2024
|
Inventor(s):
Roderic Guigo
,
Silvia Perez-Lluch
,
Marina Ruiz
Keywords(s):
Diagnostics
,
Epigenetics
,
Personalized Medicine
Category(s):
Methodology
,
Diagnostics
& Prognostics
,
Research Tools (cell lines, mice, kits, ABs, ...)
Machine-learning based forecasting of visual field deficits for glaucoma management
Summary The current technology is a machine learning algorithm that can accurately forecast glaucoma-induced visual field deficits and outperforms existing forecasting methods. This technology could allow for more efficient management of glaucoma by reducing the number of office-based visual field assessments. Technology Overview Glaucoma is characterized...
Published: 8/15/2024
|
Inventor(s):
Ashkan Abbasi
,
Hiroshi Ishikawa
,
Sowjanya Gowrisankaran
,
Xubo Song
,
Bhavna Antony
,
Gadi (Chaim) Wollstein
,
Joel Schuman
Keywords(s):
Diagnostics
,
Diagnostics
- Other
,
Software
,
Software - Diagnostic/Detection
Category(s):
Diagnostics
,
Software
Protease Activity Sensing Probes For Early Detection and Prognosis of Pancreatic Cancer
Summary The current technology is a liquid biopsy diagnostic screen for pancreatic ductal adenocarcinoma (PDAC), which is high throughput, requires very small blood volumes and has been validated in a large patient dataset. Technology Overview Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers and is typically discovered by accident...
Published: 7/31/2024
|
Inventor(s):
Jared Fischer
,
Jose Luis Montoya Mira
Keywords(s):
Diagnostics
,
Diagnostics
- Cancer
Category(s):
Diagnostics
Sealable Microvalve That Can Be Repeatedly Opened and Sealed
ink;color: #0000FF;text-decoration: underline; } INV-1243 Background The typical structure for a MEMS microvalve includes an orifice and a moveable plate that can be actuated to press against the orifice. When the plate does not press against the orifice, fluid can flow through the orifice and therefore through the valve. When the plate is pressed...
Published: 9/10/2024
|
Inventor(s):
Carol Livermore
,
Chenye Yang
Keywords(s):
Chemistry
,
Diagnostics
,
Environment
,
Homeland Security
,
Sensor Technology
Category(s):
-Chemistry
,
-Equipment
,
-Homeland Security
,
-Sensors tech
,
-Health
,
Diagnostics
,
Technology Classifications > 2. Physical Science > Environmental/Clean tech
,
Technology Classifications > 2. Physical Science > Lab tech/equipment
Analytical Device for Sorting Single Cells Based on Secreted Products
NU 2023-084 INVENTORS Shana O. Kelley* Zongjie Wang Mahmoud A. M. Labib SHORT DESCRIPTION A high-throughput, cost-effective device for sorting of single cells in a culture and analysis of their secreted products. BACKGROUND The demand for cost-effective cell analysis methods is expanding due to the increasing urge for the early detection,...
Published: 10/17/2024
|
Inventor(s):
Keywords(s):
Autoimmune disease
,
Biomedical
,
Devices
,
Diagnostics
,
Drug screening
,
Personalized medicine
Category(s):
Life Sciences > Biomarkers & Biomedical Research Tools
CD74 as a biomarker and therapeutic target for familial platelet (FPD) disorder
Summary Research at OHSU has identified the CD74 signaling cascade as a potential therapeutic target and diagnostic biomarker for RUNX1-mutated familial platelet disorder (FPD), which is a premalignant condition for acute myeloid leukemia. Technology Overview Current estimates suggest as many as 18,000 people may be living with RUNX1-FPD in the United...
Published: 2/27/2024
|
Inventor(s):
Anupriya Agarwal
,
Mona Mohammadhosseini
Keywords(s):
Diagnostics
,
Diagnostics
- Cancer
,
Diagnostics
- Other
,
Therapeutics
,
Therapeutics - Cancer
,
Therapeutics - Other
Category(s):
Diagnostics
,
Therapeutics
Acoustic Manipulation and Sampling of Lipids and Lipid Particles
Advantages: Preservation of Lipid Integrity Native Mass Spectrometry (MS) Capability Versatility and Efficiency Summary: This innovative technology addresses a significant challenge in lipid analysis, setting it apart from conventional methods. By utilizing high-frequency surface acoustic waves (SAW) for mechanical disruption of lipid...
Published: 8/16/2024
|
Inventor(s):
Theresa Evans-Nguyen
,
Venkat Bhethanabotla
,
Ashton Taylor
,
Yuqi Huang
,
Cheyenne Sircher
Keywords(s):
Biotechnology
,
Diagnostics
,
Laboratory Methods
,
Mass Spectrometry
Category(s):
Technology Classifications > Medical > Biomedical Engineering
SHIP-1 Agonists for Pancreatic Cancer Treatment
Advantages: SHIP-1 as a new molecular target to improve anti-tumor immunity and enhance immune checkpoint immunotherapy responses SHIP-1 agonists API and K306 as therapeutics for treating pancreatic cancer Combination treatment of a SHIP-1 agonist with a checkpoint inhibitor synergistically reduces tumor burden Summary: Portfolio includes...
Published: 6/11/2024
|
Inventor(s):
Tomar Ghansah
Keywords(s):
Biotechnology
,
Cancer Treatment
,
Diagnostics
Category(s):
Technology Classifications > Medical > Oncology
,
Technology Classifications > Medical > Medical
Diagnostics
Molecular Imaging of the Cochlea
Advantages: Microenvironment Sensitivity: Unveils subtle structural changes within the cochlear microenvironment, enhancing auditory health understanding. Treatment Response Tracking: Precisely quantifies potassium concentration changes, enabling accurate monitoring of treatment responses and disease progression. Non-Invasive Approach: Offers...
Published: 9/11/2024
|
Inventor(s):
Parveen Bazard
,
Mikalai Budzevich
,
Xiaoxia Zhu
,
Bo Ding
,
Robert Frisina
Keywords(s):
Diagnostics
,
Medical Imaging
Category(s):
Technology Classifications > Medical > Medical Imaging
,
Technology Classifications > Medical > Medical
Diagnostics
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