Search Results - non-cancer+therapeutics

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Precision Medicine for Psychedelic Therapies
Stress related psychiatric disorders (SRPDs) such as post-traumatic stress disorder (PTSD), major depressive disorder (MDD), mood disorders, psychotic disorders, anxiety disorders, substance use disorders (SUDs) and more, are a leading disease burden worldwide with increasing diagnoses among adolescents as well as adults. They are influenced by both...
Published: 12/11/2024   |   Inventor(s): Candace Lewis
Keywords(s):  
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals, Computing & Information Technology, Artificial Intelligence/Machine Learning
Novel Human C3 Derivatives for Therapeutic Complement Depletion
The complement system is part of the immune system and is important in both innate and adaptive immunity. However, the complement system can also be a pathogenetic factor in many diseases including, rheumatoid arthritis, reperfusion injury, myasthenia gravis, and more. Complement has also been shown to be important for the development of antibodies...
Published: 11/11/2024   |   Inventor(s): Carl-Wilhelm Vogel, Paul Finnegan, Julie Rayes, Sebastien Lacroix-Desmazes
Keywords(s):  
Category(s): Cancer Therapeutics, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Formulations to Prevent Neurological Diseases and Disorders, including TBI
Traumatic brain injury (TBI) is a major source of death and long-term physical, cognitive and mental disability worldwide, with roughly 27 million new cases each year. In the U.S. alone, this results in almost 70,000 deaths, annually. Although TBIs can affect people of all ages, the risk of getting a TBI is greatest in adolescents, young adults and...
Published: 11/4/2024   |   Inventor(s): Abhinav Acharya, Sarah Stabenfeldt
Keywords(s):  
Category(s): Vaccines/Antimicrobials, Pharmaceuticals, Non-Cancer Therapeutics, Neurodegenerative Disease Technologies, Life Science (All LS Techs)
Inflammation Targeting Contrast Agent for MR Imaging
Atherosclerosis is characterized by the formation of fatty plaque deposits within the vasculature. With increasing plaque buildup, the affected arteries may harden and narrow leading to complications such as heart attack, stroke, aneurysm and other cardiovascular events. The complex nature of plaque makes lesion-targeting imaging, and subsequently early...
Published: 7/25/2024   |   Inventor(s): Joshua Rousseau, Kuei-Chun Wang, Ting-Yun Wang
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Imaging, Medical Imaging, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Novel Vaccines and Therapeutics Against Melioidosis
Background Melioidosis, also commonly known as Whitmore’s disease, is an infection caused by the bacterium Burkholderia pseudomallei (B. pseudomallei) that currently has an estimated mortality rate of 54%. This bacteria lives in contaminated soil and surface water, and can be transmitted to humans or animals through direct contact. This bacterium...
Published: 6/11/2024   |   Inventor(s): Tung Hoang, Ian McMillan, Yun Heacock-Kang, Zhenxin (Amy) Sun, Jan Zarzycki-Siek, Michael Norris
Keywords(s):  
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Vaccines/Antimicrobials
Resveratrol and Quercetin-Loaded Nanoparticles
Obesity and related metabolic diseases are a significant public health issue in the US and worldwide. Studies have shown that pathologically expanded white adipose tissue is associated with multiple obesity-related comorbidities including diabetes, cardiovascular disease as well as certain types of cancer. Current strategies to combat obesity and metabolic...
Published: 4/29/2024   |   Inventor(s): Shu Wang, Fang Zhou, Corrie Whisner, Zhaoyang Fan
Keywords(s):  
Category(s): Nutraceuticals/Extracts, Advanced Materials/Nanotechnology, Life Science (All LS Techs), Non-Cancer Therapeutics
Multifunctional Radical Quenchers for Mitochondrial Diseases
Mitochondrial diseases are a group of disorders associated with dysfunctional mitochondria, often caused by genetic mutations to mitochondrial DNA. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Energy effecting defects have been implicated in forms of movement disorders, cardiomyopathy,...
Published: 1/25/2024   |   Inventor(s): Sidney Hecht, Arnaud Chevalier, Omar Khdour
Keywords(s):  
Category(s): Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 1/25/2024   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Nishant Visavadiya
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 1/25/2024   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Indrajit Bandyopadhyay
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine, Neurodegenerative Disorders, Parkinson's Disease, Pharmaceutical
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Multifunctional Radical Quenchers for Mitochondrial Diseases
Mitochondrial diseases are a group of disorders associated with dysfunctional mitochondria, often caused by genetic mutations to mitochondrial DNA. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Energy effecting defects have been implicated in forms of movement disorders, cardiomyopathy,...
Published: 1/25/2024   |   Inventor(s): Sidney Hecht, Omar Khdour, Mohammad Alam, Sriloy Dey, Yana Chen, Arnaud Chevalier
Keywords(s): Alzheimer's Disease, Drug Discovery, Mitochondrial medicine, Neurodegenerative Disorders
Category(s): Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics
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