Search Results - regenerative+medicine

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Compositions and Methods for Enhanced Mitochondrial Delivery for Regenerative Therapies

SHORT DESCRIPTION A novel peptide coating process that improves mitochondrial cell uptake, preserves function, and enables targeted delivery for cardiovascular and regenerative therapies. NU Tech ID NU 2025-055 INVENTORS Bin Jiang* Northwestern University Feinberg School of Medicine, Department of Surgery (Vascular...

Published: 6/18/2026 | Updated: 6/18/2026 | Inventor(s):

Keywords(s): BIO2026, Cardiology and Cardiovascular disease, MI - Myocardial Infarction, Neurodegenerative disease, Regenerative medicine, Targeted therapy, Therapeutics, Vascular disease, Vascular repair

Category(s): Life Sciences > Therapeutics

Bioactive Supramolecular Peptide Amphiphile Platforms for CNS In Vitro Models, CNS Regeneration, and Neurotherapeutic Delivery

SHORT DESCRIPTION A suite of self‑assembling peptide amphiphile nanostructures and hydrogels that mimic key neurotrophic factors, modulate ionic and electrical microenvironments, and protect therapeutic peptides to enhance neural survival, maturation, and regeneration across CNS diseases and injuries INVENTORS Samuel I Stupp Weinberg...

Published: 6/16/2026 | Updated: 6/16/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, ALS - Amyotrophic Lateral Sclerosis, BIO2026, Biomaterials, CNS - Central Nervous System, Drug delivery, Drug discovery, Drug screening, Hydrogel, In vitro models, Neurology, PD - Parkinson's Disease, Regenerative medicine, Research tool, Scaffold, SCI - Spinal cord injury, Smart/Functional materials, Therapeutics

Category(s): Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

Epigenetic Gene Editing in Cardiomyopathy to Improve Heart Function

SHORT DESCRIPTION A precision cardiac gene‑regulation platform that deletes a MYH7 enhancer to shift ventricular myosin isoform balance toward faster α‑MHC and activates upstream MYH6 enhancers to increase MYH6 expression and improve contractility, creating a dual toolkit for disease‑modifying therapy in cardiomyopathy and heart failure. INVENTORS Elizabeth...

Published: 6/16/2026 | Updated: 5/12/2026 | Inventor(s):

Keywords(s): BIO2026, Cardiology and Cardiovascular disease, Cardiomyopathy, Gene therapy, Regenerative medicine, Therapeutics

Category(s): Life Sciences > Therapeutics

Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications

SHORT DESCRIPTION Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry Anna Metlushko Bo...

Published: 6/16/2026 | Updated: 4/30/2026 | Inventor(s):

Keywords(s): BIO2026, Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

Interoceptomimetics: Dietary Supplements to Enhance Exercise Motivation and Performance

Enhancing exercise performance by modulating the activity of motivation-generating brain regions via stimulation of cannabinoid (CB1) receptors of the enteric nervous system. Problem: An increase in sedentary lifestyles driven by the modernization of society has led to a surge in several metabolic and neurological diseases worldwide. Although exercise...

Published: 4/30/2026 | Updated: 4/30/2026 | Inventor(s): Christoph Thaiss, John Nicholas Betley

Keywords(s): Aging, Cardiovascular, Healthcare IT, Microbiome, Neurology, Obesity Metabolic Disease and Diabetes, Regenerative Medicine, Small Molecule

Category(s): Technology Classifications > Food Science and Nutrition, Technology Classifications > Therapeutics

Precision Gene Therapy for Diseases Driven by Endothelial Dysfunction

SHORT DESCRIPTION Dual promoter system constructs for tissue-specific and cell-type-specific gene expression, enabling precision gene therapy targeting endothelial dysfunction in specific organs. INVENTORS Youyang Zhao* Ann & Robert H Lurie Children's Hospital of Chicago * Principal Investigator NU...

Published: 6/16/2026 | Updated: 4/27/2026 | Inventor(s):

Keywords(s): BIO2026, Cardiology and Cardiovascular disease, CMD - Cardiometabolic disease, CPD - Cardiopulmonary disease, Gene therapy, Pulmonary disease, Regenerative medicine, Targeted therapy, Therapeutics, Vascular disease

Category(s): Life Sciences > Therapeutics

Next Gen Immune-Optimized Gene Delivery

Application An advanced gene therapy approach that improves therapeutic efficiency by protecting transgene expressing cells from host immune responses, through modulation of a key immune checkpoint pathway. Key Benefits Enhanced efficiency across viral and non-viral gene delivery systems, including AAV, lentivirus, LNPs, and electroporation. Enables...

Published: 6/15/2026 | Updated: 2/23/2026 | Inventor(s): Matthew (Matt) Gardner, Michael Kuipa, Abubakarr Koroma, Isai Leguizamo

Keywords(s): Biologics, Cell Therapy, Gene Therapy and Editing, Immunology and Inflammation Treatments, Oncology Treatments, Platform, Regenerative Medicine

Category(s): TechPub Algolia > Therapeutics

Netrin-1 Mimetic Peptide Amphiphile Assemblies for Enhanced CNS Regeneration

NU 2024-174 INVENTORS Samuel Stupp* Cara Smith Zaida Alvarez Pinto SHORT DESCRIPTION Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration. BACKGROUND Neurotrophic factors are essential for the development and regeneration of neurons; however,...

Published: 6/16/2026 | Updated: 2/20/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, BIO2026, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Nanotechnology, Neurodegenerative disease, Regenerative medicine, SCI - Spinal cord injury, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Protein Polymers for Organelle Engineering

Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...

Published: 5/22/2026 | Updated: 11/7/2025 | Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla

Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools

Category(s): TechPub Algolia > Therapeutics

A New High-Throughput Cell Biology Method to Screen for Genes Critical for Cell Differentiation

A high-throughput method for identifying genes involved in the process of stem cell differentiation into specialized cells. Background: One of the many draws of stem cells is their potential for regenerating tissues, nerves, and other organs, but the differentiation potential of stem cells is highly regulated by genes. Therefore, the ability to...

Published: 6/26/2026 | Updated: 5/13/2025 | Inventor(s): Chunyu Liu

Keywords(s): cell culture, development, differentiation, high-throughput, neuroscience, regenerative medicine, screen

Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines

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