Search Results - life+science+research+tools

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Highly Miniaturized Closed-Loop Biosensing and Drug Delivery (Case No. 2025-276)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an implantable closed-loop system that integrates electrochemical biosensing, wireless signal transmission, and programmable drug release. Background: Conventional disease management systems rely on single-point measurements and discrete interval drug...
Published: 2/5/2026   |   Inventor(s): Aydin Babakhani, Iman Habibagahi, Hamid Jafarisharemi, Roshan Mathews
Keywords(s): biomedical implantation, biomedical sensors, Drug Delivery, Drug monitoring, Implant (Medicine), implantable sensors, Medical Device, minimally invasive drug delivery systems, on-demand drug delivery, personalized dose assessment, Smart medical device, Therapeutics, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health, Wireless, wireless communication
Category(s): Life Science Research Tools, Electrical, Medical Devices, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms
Lesion Estimation with Geometric Object Measurement (LE-GEOM) (Case No. 2025-077)
Summary: UCLA researchers in the Department of Radiology have developed a novel, automated approach for tumor assessment by determining RANO-compliant tumor diameters from tumor segmentation data. Background: MRI tumor measurements are critical in both clinical trials and clinical practice. Traditionally, radiologists manually assessed tumors by...
Published: 2/19/2026   |   Inventor(s): Benjamin Ellingson, Francesco Sanvito, Catalina Raymond
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Bioinformatics
An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...
Published: 1/13/2026   |   Inventor(s): Pei-Yu Chiou, Xiang Zhang
Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping
Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies
Mental Health Functional Movement Scale (MH-FMS) (Case No. 2025-021)
Summary: UCLA researchers in the Department of Psychiatry and Behavioral Sciences have created a novel assessment platform that objectively measures how the brain, body, and autonomic nervous system respond to stress and regulate emotion during real-time movement. By integrating a shear-stress–based neurovascular framework with a polyvagal-informed...
Published: 12/17/2025   |   Inventor(s): Naser Ahmadi, Mike Ramirez, Julien Pineau
Keywords(s): blood flow management, Cardiovascular, cellular, clinical care methodology, clinical decision support, Clinical decision support system, clinical mental health, Clinical tool, exercise physiology, Hemodynamics, Mental health, neurobehavioral impairment, Neurocognitive, Neurocognitive Scientific Method, neurodevelopment, neurological disorders, Neuropsychological Test, neuroscience, Neurostimulation, Psychiatry / Mental Health
Category(s): Diagnostic Markers, Life Science Research Tools, Medical Devices, Medical Devices > Hospital Systems, Therapeutics, Therapeutics > Psychiatry And Mental Health
Machine Learning to Predict Physiological Age Using Features Extracted From Arterial Blood Pressure (ABP) Waveforms (Case No. 2025-264)
Summary: UCLA researchers in the Department of Anesthesiology have introduced a novel machine learning model that accurately predicts physiological aging by analyzing features extracted from patients’ arterial blood pressure (ABP) waveforms. This approach enables efficient, data-driven assessment of biological aging in clinical settings to facilitate...
Published: 12/5/2025   |   Inventor(s): Maxime Cannesson, Ravi Pal
Keywords(s): Aging, Anesthesiology, biomedical sensors, clinical care methodology, clinical decision support, clinical outcome, Clinical tool, Computer-Aided Diagnosis, consumer health products, Digital Health, digital health system, Fatigue (Medical) , Health and fitness, health risk assessment, Machine Learning, machine learning modeling, Medical Device, Medical diagnostics, Monitoring (Medicine), personalized medicine, Preventive Medicine, public health monitoring, Smart medical device, Structural health monitoring, Telemedicine
Category(s): Diagnostic Markers, Diagnostic Markers > Aging, Life Science Research Tools, Medical Devices
Broad-Band Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Neuropsychiatric Disorders (Case No. 2025-99J)
Summary: Researchers in UCLA's Semel Institute and Department of Psychiatry have developed an innovative approach to treating depression by optimizing repetitive Transcranial Magnetic Stimulation (rTMS), improving its effectiveness for the treatment of Major Depressive Disorder (MDD) and possibly diseases of the mind and brain. Background: Depression...
Published: 10/16/2025   |   Inventor(s): Andrew Leuchter, Juliana Corlier, Thomas Valles
Keywords(s): Bioelectromagnetics, Brain, Deep Brain Stimulation, Electrical Brain Stimulation, energy-efficient, frequency modulation, Magnetic Field, Medical Device, medication efficacy, neural information, neural network, neural networks, neural signals, neural stimulation, neurobehavioral impairment, Neurocognitive, neurological disorders, Neuromodulation, Neuron, neurons, neuroscience, Neurostimulation, pulsed load modulation, therapy, treatment efficacy
Category(s): Medical Devices, Medical Devices > Neural Stimulation, Life Science Research Tools, Therapeutics > CNS and Neurology, Therapeutics
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)
Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...
Published: 9/25/2025   |   Inventor(s): Michael Teitell, James Gimzewski, Jason Reed
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems
Pulsed Laser Triggered High Speed Microfluidic Switch and Applications in Flourescent Activated Cell Sorting (Case No. 2009-063)
Summary UCLA researchers have developed a pulsed-laser triggered microfluidic switching mechanism capable of sub-100 µs switching (e.g. ~70 µs), enabling ultrafast cell/particle sorting in a microfluidic fluorescence-activated cell sorting (µFACS) platform using cavitation bubbles rather than mechanical valves. Background Flow cytometry...
Published: 9/25/2025   |   Inventor(s): Pei-Yu Chiou, Ting Hsiang Wu
Keywords(s):  
Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods
TRP: Precursor Towards 18F-Clofarabine (UCLA Case No. 2017-379)
Tangible Research Property (TRP) Contact UCLA Technology Development Group to learn more.
Published: 9/29/2025   |   Inventor(s): Caius Radu
Keywords(s):  
Category(s): Life Science Research Tools
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