Search Results - memory

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Use of Neurotrophic Factor-alpha1/Carboxypeptidase E (CPE) to Treat Alzheimer Disease
Abstract: There is no known cure for Alzheimer’s disease, a brain disorder that severely affects memory, thinking, learning, and organizing skills. It eventually decreases a person’s ability to carry out simple, daily activities. It is predicted that over 14 million Americans will develop Alzheimer’s without effective treatment options. Mild cognitive...
Published: 4/8/2024   |   Inventor(s): Yoke Loh, Yong Cheng
Keywords(s): “Cognitive impairment”, Ad, Alzheimer’s Disease, BNDF, brain, Brain-Derived Neurotrophic Factor, Carboxypeptidase E, CPE, Hippocampus, LOH, MCI, MEMORY, Mild Cognitive Impairment, NEURODEGENERATION, NEUROTROPHIC
Category(s): TherapeuticArea > Neurology, Application > Therapeutics, Collaboration Sought > Licensing
Single-Cycle Processing-in-SRAM Logic Circuit Design
Traditional von-Neumann computing architectures, such as CPUs and GPUs, demonstrate limitations in memory bandwidth and energy efficiency. However, their high demand lies in their programmability and flexible functionality. Such platforms execute a wide spectrum of bit-wise logic and arithmetic operations. In this regard, recent application-specific...
Published: 7/15/2023   |   Inventor(s): Deliang Fan, Shaahin Angizi
Keywords(s): Algorithm Development, Circuits, Computational Machine, Computing Architecture, Electronics, Memory, PS-Computing and Information Technology
Category(s): Computing & Information Technology, Physical Science
Temperature-Resilient RRAM-Based In-Memory Computing for DNN Inference
Deep neural networks (DNNs) have shown extraordinary performance in recent years for various applications, including image classification, object detection, speech recognition, etc. Accuracy-driven DNN architectures tend to increase model sizes and computations in a very fast pace, demanding a massive amount of hardware resources. Frequent communication...
Published: 5/2/2023   |   Inventor(s): Jae-Sun Seo, Jian Meng, Li Yang, Deliang Fan
Keywords(s): Algorithm Development, Machine Learning, Memory, Neural Computing, PS-Computing and Information Technology
Category(s): Computing & Information Technology, Physical Science
Novel Roles of a DNA Repair Protein, DNA-PKcs, in Obesity, Neurological Function, and Aging
The catalytic subunit of the DNA-dependent protein kinase complex (DNA-PKcs) has been shown to be important in DNA repair and VDJ recombination in lymphocytes. The inventors have discovered that DNA-PKcs also plays novel, important roles in energy regulation and neurological function. The inventors observed that mature DNA-PKcs-deficient mice (also...
Published: 7/25/2024   |   Inventor(s): Jay Chung
Keywords(s): Aging, ANXIETY, Cardiovascular, depression, DIABETES, DNA-Dependent, DNA-PKcs, Endurance, Energy, HEART, IB1XXX, IB3XXX, IB6XXX, IBXXXX, Inflammation, insulin, INSULIN-DEPENDENT, IXXXXX, LEARNING, MEMORY, METABOLIC, Metabolism, Mitochondria, Neurological, OBESITY, REGULATION, TYPE-2, Weight
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Cardiology, TherapeuticArea > Reproductive Health, TherapeuticArea > Immunology
Charge Trap Transistors - Subramanian Iyer
Background: Due to their chemical makeup and heat generation, devices such as high-k/metal gate (HKMG) CMOS often accumulate charges can lead to variation in integrated circuits. Charge Trap Transistors (CTT's) utilize accumulating charge in semiconducting devices as embedded non-volatile memory (eNVM). The introduction of CTT's can prove an...
Published: 7/19/2023   |   Inventor(s): Subramanian Iyer
Keywords(s): Charge Carrier, CMOS, Dynamic Random-Access Memory, Electrical, Electrical Engineering, Electrical Load, Electrical Resistance And Conductance, Logic Gate, Magnetoresistive Random-Access Memory, Medical Device, Memory, Power Electronics, Power Transmission, Programmable Logic Device, Random-Access Memory, Resistive Random-Access Memory, Semiconductor Device, Semiconductor Device Fabrication, Static Random-Access Memory, Transistor
Category(s): Electrical, Electrical > Electronics & Semiconductors > Memory, Electrical > Electronics & Semiconductors
2021-278 Enhancement of Human Memory and Treatment of Alzheimer’s Disease by Closed -Loop Phase-Locked Brain Electric Stimulation During Sleep
­SUMMARY: UCLA researchers in the department of Neurosurgery have developed an implantable brain electrode system which can modulate the brain’s activity to improve sleep and consolidation of memory, several important activities in the treatment of Alzheimer’s Disease. BACKGROUND: Sleep is universally understood to be beneficial to...
Published: 7/19/2023   |   Inventor(s): Itzhak Fried, Yuval Nir, Maya Geva-Sagiv
Keywords(s): Deep Brain Stimulation, Deep Brain Stimulation Current Mirror Output Impedance, Electrical Brain Stimulation, Memory, Neurocognitive, Neurodegeneration, Neurodegeneration Alzheimer's Disease Predictive Testing, Neuromodulation, Neurostimulation
Category(s): Medical Devices > Neural Stimulation, Medical Devices > Monitoring And Recording Systems
Tunable and Reconfigurable Atomically Thin Heterostructures
3 layers can form rotationally-aligned stacks with long-range crystallographic order. Our theory predicts and experiments reveal striking electronic and optical changes when Bi2Se3 is stacked layer-by-layer on monolayer MoS2, including the formation of an indirect bandgap and 100% photoluminescence (PL) suppression, tunable transmittance-edge (1.1 eV®0.75...
Published: 9/10/2024   |   Inventor(s): Swastik Kar, Fangze Liu, Christopher Lane, Daniel Rubin, Arun Bansil, Anthony Vargas, Zachariah Hennighausen
Keywords(s): Data Storage, Devices, Electronics, Energy Technology, Materials, Memory, Optoelectronics
Category(s): -Chemistry, -Materials, -Optics, -Nanotechnology, -Sensors tech, Technology Classifications > 2. Physical Science > Electronics/Semiconductors
An infrastructure for memory management on LLM multi-core architectures
Limited Local Memory (LLM) multi-core architectures substitute cache with scratch pad memories (SPM). As a result, SPMs have much lower power consumption compared to other multi-core architectures. However, SPMs lack an automatic memory management system which presents a challenge to programmers as heap data sizes may be variable and data dependent....
Published: 2/23/2023   |   Inventor(s): Ke Bai, Aviral Shrivastava
Keywords(s): Algorithm Development, Cyber-Physical System, Memory, Simulation, Software
Category(s): Wireless & Networking
An Efficient Stack Data Management for Scratchpad Memory based Multi-core Processors
As technology scales, the number of cores in processors will rapidly increase in order to avoid the power wall. In processors that have hundreds and thousands of cores, traditional memory architectures – in which a coherent memory interface is provided to all the cores in hardware, will not be feasible. The memory management functionality is expected...
Published: 2/23/2023   |   Inventor(s): Ke Bai, Jing Lu, Aviral Shrivastava
Keywords(s): Algorithm Development, Cyber-Physical System, Memory, Software
Category(s): Computing & Information Technology
2014-322 MAGNETIC MEMORY BITS WITH PERPENDICULAR MAGNETIZATION SWITCHED BY CURRENT-INDUCED SPIN-ORBIT TORQUES
Magnetic Memory Bits with Perpendicular Magnetization Switched By Current-Induced Spin-Orbit TorquesTech ID: 30203 / UC Case 2014-322-0SUMMARYUCLA researchers in the Department of Electrical and Computer Engineering have developed a novel spin-orbit-torque (SOT)-controlled magnetic random access memory driven by in-plane currents.BACKGROUNDMagnetization...
Published: 7/19/2023   |   Inventor(s): Kang Wang
Keywords(s): Electronics & Semiconductors, Memory
Category(s): Electrical > Electronics & Semiconductors, Electrical > Electronics & Semiconductors > Memory
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