Search Results - biotechnology

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Lab on a 3D Printer (Case No. 2025-094)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel device capable of performing automated liquid handling to a great degree of precision on a miniaturized scale and with customizable features equipped for any laboratory task. Background: Automated liquid handling is essential in pharmaceutical and biotechnology research...
Published: 7/2/2025   |   Inventor(s): Dino Di Carlo, Shun Ye, Zixin Guan, Artem Goncharov, Vivek Rajasenan, Charlotte Rose McDonough, Tristan Lovely
Keywords(s): 3D biofabrication, 3D Printing, Automation, bioimaging, biomanufacturing, Biomaterial 3D Printing, Biomonitoring, Biosensor, Biotechnology, Drug Discovery, fluid mechanics, graphical user interface, Liquid tracking, mechanical durability, Robotic liquid handling
Category(s): Life Science Research Tools, Medical Devices, Diagnostic Markers, Life Science Research Tools > Lab Equipment, Mechanical
Computerized Cognitive Training for Insomnia (COGMUSE)
Advantages Gamified cognitive training that is aimed at adults with both autism and insomnia Flexibility in terms of the ability to incorporate user feedback Summary Older adults with insomnia as well as autistic adults with co-occurring insomnia often struggle with persistent cognitive and sleep disturbances. These issues are only marginally...
Published: 5/30/2025   |   Inventor(s): Ashley Curtis
Keywords(s): Biotechnology, Computer Science, Computers Software and Information Technology, Health Tech, Human Computer Interfaces, Neuroscience, Psychiatry / Mental Health, Therapeutics
Category(s): Technology Classifications > Computer Science > Computers Software & Information Technology, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics, Technology Classifications > Engineering > Computer Engineering
Drill Guide/Suture Passer for Posterior Approach Total Hip Soft Tissue Repair
­Combined drill guide and suture passer for use in assisting repair following posterior approach total hip arthroplasty. Background: The posterior approach to the hip for total hip replacement as well as trauma, pediatric orthopedic surgery, and tumors is the most common approach for total hip arthroplasties. However, the performance of this...
Published: 5/13/2025   |   Inventor(s): Timothy Damron
Keywords(s): biomedical engineering, biotechnology, hardware, healthcare, medical devices, medical equipment, orthopedics, surgery, suturing technique, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices
DsDNA-templated Substrates as Fluorescent Probes for CRISPR-Cas12a-based Diagnostics
New design for CRISPR-based fluorescent probes improves disease diagnostics and sensing. Background: Scientists use the naturally occurring CRISPR-Cas12a gene editing system as a valuable tool for disease diagnostics. When Cas12a finds its target -- a sequence of double-stranded DNA -- it cuts it. In the process, it also cuts other nearby DNAs. Scientists...
Published: 5/13/2025   |   Inventor(s): Mehmet Yigit, Christopher Smith
Keywords(s): agriculture, biotechnology, Cas12a, Cas12a, CRISPR, CRISPR, detection, detection, DNA, DNA, fluorescence, fluorescence, RNA, RNA, sensor, sensor
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
Wireless, Miniaturized Sensing Platforms for Inflammatory Bowel Diseases
­LUNU 2023-223 INVENTORS John Rogers* Arun Sharma* Surabhi Madhvapathy Matthew Bury SHORT DESCRIPTION Miniaturized, implantable temperature sensors for real-time, minimally invasive monitoring of inflammatory bowel diseases. BACKGROUND Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, affects over 10...
Published: 6/10/2025   |   Inventor(s):  
Keywords(s): Autoimmune disease, Biomedical, Biotechnology, Devices, Diagnostics, Electronics & Circuits, Gastrointestinal and Hepatic disease, Healthcare, Medical device, Obesity, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Engineered Lipid Tags for Extracellular Vesicle Loading
NU 2022-178 INVENTORS Neha Kamat* Joshua Leonard* Justin Alexander Peruzzi Taylor Gunnels SHORT DESCRIPTION This technology enhances the loading of protein cargo into extracellular vesicles (EVs) by directing protein association with membrane lipid rafts, utilizing engineered lipid tags for targeted delivery. BACKGROUND Extracellular...
Published: 6/10/2025   |   Inventor(s):  
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Leveraging Lipid-Protein Interactions to Engineer Spatial Organization in Cell-free Systems
NU 2021-231 INVENTORS Neha Kamat* Justin Alexander Peruzzi Jan Steinkuehler SHORT DESCRIPTION This innovative method enables the control of membrane protein location and distribution in synthetic lipid membranes using lipid-protein interactions, without chemical conjugation, facilitating the development of advanced cell-free systems. BACKGROUND Spatially...
Published: 6/10/2025   |   Inventor(s):  
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Physical Sciences > Engineering & Technology
New Target for Heart Failure Therapies: Modifying MRPS5/ATF4 Signaling in Cardiomyocytes
Advantages: Identification of MRPS5 as a Therapeutic Target: Reduction of MRPS5 expression stimulates cardiomyocyte proliferation and enhances heart function Discovery of the MRPS5 signaling axis: Decreased MRPS5 enhances ATF4 and Knl1, which promote cardiomyocyte, boosting cardiac recovery after myocardial injury Improved Survival and Cardiac...
Published: 1/17/2025   |   Inventor(s): Da-Zhi Wang, John Mably
Keywords(s): Biotechnology, Cardiological Diseases Treatment, Cell & Tissue Culture & Engineering, Medical Diagnostics, Pharmaceuticals
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Pharmaceuticals
Sensitive and Selective Synthetic Glucose Receptor for Diagnostic Applications
Advantages: Highly sensitive glucose sensor with strong potential for use in biomedical diagnostics and continuous glucose monitoring. Flexible, adaptive binding pocket that selectively targets glucose’s functional groups, improving specificity and detection accuracy. Reversible, non-covalent binding to glucose, allowing real-time response...
Published: 5/5/2025   |   Inventor(s): Wenqi Liu
Keywords(s): Biotechnology, Diabetes, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical
Aesthetics and Wound Healing-related Technologies
NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-071; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094 Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes hydrogels...
Published: 6/10/2025   |   Inventor(s):  
Keywords(s): Adhesive, Biomedical, Biotechnology, General surgery, Hydrogel, Wound Healing
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT
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