Search Results - biomanufacturing

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Downregulation of Promoter Strength for Increased Production of Recombinant Biopolymers
RPI ID: 2021-070-401 Innovation Summary: Recombinant E. coli strains and synthetic protein sequence designs are used to produce disordered polypeptides such as spidroins and elastin-like peptides (ELPs). The system leverages genome engineering to suppress basal expression and redirect cellular resources toward target biopolymer synthesis. This approach...
Published: 3/10/2026   |   Inventor(s): Mattheos Koffas, Derek Nelson, Runye Zha, Alexander Connor
Keywords(s): Biomanufacturing, Biomaterials, Recombinant Protein Engineering, Sustainable Materials
Category(s): Biotechnology and the Life Sciences
Upcycling of Plastic Waste to Recombinant Silk Proteins via Pseudomonas sp
RPI ID: 2021-045-401 Innovation Summary: This method uses engineered Pseudomonas bacteria to convert plastic waste into recombinant silk proteins. The system includes metabolic pathways that degrade polyethylene terephthalate (PET) and redirect carbon into silk protein synthesis. It supports circular bioeconomy models and reduces environmental impact....
Published: 3/10/2026   |   Inventor(s): Runye Zha, Mattheos Koffas, Alexander Connor
Keywords(s): Advanced Materials, Biomanufacturing, Metabolic Engineering, polymer upcycling, sustainability
Category(s): Biotechnology and the Life Sciences
Lab on a 3D Printer (Case No. 2025-094)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel device capable of performing automated liquid handling to a great degree of precision on a miniaturized scale and with customizable features equipped for any laboratory task. Background: Automated liquid handling is essential in pharmaceutical and biotechnology research...
Published: 8/21/2025   |   Inventor(s): Dino Di Carlo, Shun Ye, Zixin Guan, Artem Goncharov, Vivek Rajasenan, Charlotte Rose McDonough, Tristan Lovely
Keywords(s): 3D biofabrication, 3D Printing, Automation, bioimaging, biomanufacturing, Biomaterial 3D Printing, Biomonitoring, Biosensor, Biotechnology, Drug Discovery, fluid mechanics, graphical user interface, Liquid tracking, mechanical durability, Robotic liquid handling
Category(s): Life Science Research Tools, Medical Devices, Diagnostic Markers, Life Science Research Tools > Lab Equipment, Mechanical
2021-285 Chemical Stimulation of Cellular Contractability to Enhance the Quality of Cultured Meat
Summary: UCLA researchers in the Department of Integrative Biology and Physiology have developed a novel methodology to improve the texture and overall quality of muscle grown ex vivo for sustainable biomanufacturing applications. Background: Livestock production is known to be ecologically expensive due to its use of large swaths of land and release...
Published: 7/17/2025   |   Inventor(s): Amy Rowat
Keywords(s): Beyond meat, biomanufacturing, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, Food Chain, meat, meat production, Sustainable nutrition
Category(s): Chemical, Therapeutics > Agtech And Animal Health