Search Results - osteoarthritis

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Tibial Tubercle Osteotomy Fixation Device
Fixation device to secure bone fragment of tibial tuberosity to native bone after osteotomy surgical procedure. Background: Standard osteotomy techniques to join the tibial tubercle fragment to native bone include screw fixation alone or fixation with wire or suture, which are not reliable methods to holding the bone in place to avoid displacement...
Published: 5/7/2024   |   Inventor(s): Timothy Damron
Keywords(s): biomedical, biomedical engineering, hardware, healthcare, instrumentation, medical devices, medical equipment, orthopedics, osteoarthritis, surgery, suturing technique, Technologies
Category(s): Technology Classifications > Medical Devices, Campus > Upstate Medical University
Monoclonal Antibody Fragments for Targeting Therapeutics to Growth Plate Cartilage
Abstract: A child's growth is dependent on the proper functioning of the growth plate, a specialized cartilage structure located at the ends of long bones and within the vertebrae. The primary function of the growth plate is to generate new cartilage, which is then converted into bone tissue and results in the lengthening of bones. Failure of the growth...
Published: 4/8/2024   |   Inventor(s): Jeffrey Baron, Sao Fong (Crystal) Cheung, Chun Lui, Dimiter Dimitrov, Zhongyu Zhu
Keywords(s): Anti-mantrilin-3 Antibody, ARTHRITIS, Baron, Cartilage, Dimitrov, Eunice Kennedy Shriver National Institute on Child Health an, Growth plate, Human Growth Hormone, monoclonal, NICHD, OSTEOARTHRITIS, Short Stature, Skeletal Dysplasia
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics
Occupational Health: Wearable Kneel-Sit Support Device for Manual Labor and Heavy Industry Applications
This CDC-developed technology describes a novel ergonomic device that supports a portion of the worker's weight while kneeling, relieving the knee pressure and pain common to many manual labor occupations. Unfortunately, many of the devices that have been used in the past to relieve pressure on the knees are bulky, heavy, and of questionable durability. This...
Published: 7/25/2024   |   Inventor(s): Ova Johnston, Stephen Hudock, Steven Wurzelbacher
Keywords(s): AB1XXX, AB3GXX, AB3XXX, AE2BXX, AE2XXX, AE4XXX, AEXXXX, AFXXXX, ARTHRITIS, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DEVICE, Knee, Kneel-sit, LABOR, MINING, NIOSH, NIOSH-DART, OSHA, OSTEOARTHRITIS, SAFETY, SUPPORT, VAXXXX, VMXXXX, VPXXXX, Wearable, WEXXXX, WGXXXX, WMXXXX, WORK, WORKER, WORKER safety, WORKERS, XDXXXX, XIXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Medical Devices, TherapeuticArea > Geriatrics, Application > Occupational Safety and Health, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, TherapeuticArea > Immunology, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease
Osteoanabolism by 14-3-3zeta
Project ID: D2021-48 Background Bone loss is one of the common symptoms associated with normal aging and pathologies. An increased bone mass loss and mineral density are the primary reason for osteoporosis, arthritis, fractures, etc. Together it affects millions of individuals in the US alone. While several drugs targeting the prevention of bone...
Published: 6/18/2024   |   Inventor(s): Ritu Chakravarti, Saurabh Chattopadhyay
Keywords(s): 14-3-3z, 14-3-3 zeta, Arthritis, Autoimmune, Osteoarthritis, Rheumatoid Arthritis
Category(s): Inflammation & Immunity, Long Bone/Joint Repair
Bioactive Nanoparticles for an Osteoarthritis Therapeutic
Neutralizes Reactive Oxygen Species to Reduce Oxidative Stress in Osteoarthritic TissueThese nanoparticles break down the reactive oxygen species (ROS) generated during joint trauma and inflammation, thereby mitigating oxidative stress in order to treat or prevent osteoarthritis (OA) as well as other inflammatory diseases. Oxidative stress plays a central...
Published: 6/27/2021   |   Inventor(s): Blanka Sharma, Isaac Adjei, Shreedevi Kumar
Keywords(s): Maganese Disorder, MNO2, Nanoparticle, osteoarthritis, Oxidative stress, PEG, Poly ethylene glycol, Reactive Oxygen Species, ROS
Category(s): Technology Classifications > Human Health Care > Therapeutics