Search Results - non-small+cell+lung+cancer

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A Ventilated Artificial Human Lung Exposure System to Analyze and Test Human Exposures to Inhaled Substances (Case No. 2023-306)
Summary: UCLA researchers in the Department of Medicine and Environmental Health Sciences have developed a ventilated human lung system for laboratory testing of inhaled substances. Background: Measuring the toxicology of inhaled air, aerosols and other substances is challenging due to the complexity of human studies and limitations in existing...
Published: 3/27/2025   |   Inventor(s): Michael Roth, Airi Harui, Yifang Zhu, Haoxuan Chen
Keywords(s): aerosol, Angiogenesis Acute Lung Injury, bioaerosol, cardiopulmonary illness, Cellular Respiration, consumer goods and products, Lung, Lung Pulmonology, non-small cell lung cancer, Preclinical model development, Preclinical surgical innovation, pulmonary arterial pressure (PAP), pulmonary failure, Pulmonary fibrosis, Respiratory & Pulmonary, respiratory failure, right atrial to pulmonary canula, Simulation & Modeling, simulation model, small cell lung cancer
Category(s): Platforms, Platforms > Drug Delivery, Life Science Research Tools, Life Science Research Tools > Research Methods, Therapeutics, Therapeutics > Respiratory And Pulmonary, Mechanical, Mechanical > Sensors
Combination Cancer Therapy Methods and Agents (UCLA Case No. 2024-084)
UCLA researchers from the Department of Medicine, Pathology, & Laboratory Medicine and Molecular & Medical Pharmacology have identified a novel cell-based therapy that leads to enhanced immunotherapy efficacy and overcomes treatment resistance to immune checkpoint blockade in non-small cell lung cancer. BACKGROUND: Non-small cell lung cancer...
Published: 2/14/2025   |   Inventor(s): Bin Liu, Steven Dubinett
Keywords(s): anti-tumor immunity, cell-based therapy, Immune checkpoint blockade, Immunotherapy, non-small cell lung cancer, treatment resistance, Tumor microenvironment, Vaccines
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Respiratory And Pulmonary
Nanoparticle delivery of lung cancer therapeutic
Abstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in developed countries.  Despite the availability of several synergistic, targeted therapy regiments, the 5-year survival rate for NSCLC is only 15%.  The poor prognosis of NSCLS is due in part to limitations of current treatments, which do not trigger an immune...
Published: 5/22/2024   |   Inventor(s): Dennis Klinman, Takashi Sato (Unable To Locate)
Keywords(s): Immunotherapy, Nanoparticle, Non-small cell lung cancer, NSCLC
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology
Non-invasive diagnostic and prognostic assay for early stage lung cancer
Abstract: In the United States alone, one of four cancer deaths occur from lung cancer and there are over 8 million individuals considered to be at high-risk due to cigarette smoking and other behaviors. It's well known that early detection of cancer significantly improves survival of this disease, however a lack of lung cancer screenings and analysis...
Published: 4/8/2024   |   Inventor(s): Curtis Harris, Ewy Mathe, Frank Gonzalez, Kristopher Krausz, Soumen Manna, Andrew Patterson, Majda Haznadar
Keywords(s): LDCT, LD-CT, liquid biopsy, low-dose computed tomography, Non-small cell lung cancer, NSCLC, Urine
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Diagnostics, Collaboration Sought > Licensing