Search Results - resolution

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Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems (Case No. 2023-290)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel label-free optical mapping method for profiling real-time biomechanical dynamics over larger areas with high spatiotemporal resolution. Background: Mapping biomechanical dynamics often involves the use of various advanced technologies to measure...
Published: 6/27/2024   |   Inventor(s): Pei Yu Chiou, Yen-Ju Lin
Keywords(s): bioimaging, Biomechanics, cell imaging, Confocal Microscopy, dye, Fluorescence Microscope, labeling, Microscopy, Microscopy And Imaging, resolution, traction force microscopy
Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Cell Counting And Imaging, Medical Devices, Medical Devices > Medical Imaging, Platforms, Platforms > Diagnostic Platform Technologies
Resolution Enhancement for Line-Scanning Excitation Microscopy
The invention describes a method for improving the spatial resolution of optical microscopes that use line-scanning excitation, such as line-scanning confocal microscopes, line-scanning STED microscopes, or line-scanning light-sheet microscopes. Common elements of the invention include: a) an apparatus for exciting and scanning a line-like excitation...
Published: 7/25/2024   |   Inventor(s): Andrew York, John Giannini, Abhishek Kumar, Hari Shroff
Keywords(s): AC1XXX, AC2XXX, AC3XXX, fluorescent, MICROSCOPE, MICROSCOPY, RESOLUTION, XDXXXX, XFXXXX, YFXXXX
Category(s): Collaboration Sought > Collaboration, Application > Software / Apps, Application > Non-Medical Devices, Application > Medical Devices, Application > Diagnostics
Rapid Detection of Multi-Drug-Resistant Mycobacterium tuberculosis Using Real-Time PCR and High-Resolution Melt Analysis
CDC scientists have developed a rapid, sensitive, and specific real-time PCR assay that is capable of detecting the presence of Mycobacterium tuberculosis and determining its resistance profile to antibiotics, such as rifampicin and isoniazid. Currently, there are few assays available that are capable of both detecting M. tuberculosis and determining...
Published: 7/25/2024   |   Inventor(s): Jonas Winchell, Kelley Cowart, Melissa Ramirez, James Posey
Keywords(s): analysis, DA3XXX, DAXXXX, Detection, DXXXXX, High, Melt, Multidrug, PCR, PROCESS, REAL-TIME, RESISTANT, RESOLUTION, TUBERCULOSIS, Tuberculosis (Mycobacterium tuberculosis)
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics
Software to Improve the Quality of Microscopy Images
Available for licensing and commercial use is software based on an iterative deconvolution procedure that recovers images that have been blurred by a known point spread function. The software provides superior results when multiple independent observations of the same specimen are obtained. An example of such observations might be the multiple views...
Published: 4/8/2024   |   Inventor(s): Andrew York, Yicong Wu, Hari Shroff
Keywords(s): AC2XXX, AC3XXX, ACXXXX, AD1XXX, ADXXXX, AXXXXX, Deconvolution, image quality, IMAGING, MICROSCOPY, RESOLUTION, Signal-to-Noise, software
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Multi-Photon Microscopy System Configured for Multiview Non-Linear Optical Imaging
This invention is a microscopy device and system for multi-photon microscopy utilizing multi-view nonlinear optical imaging. Nonlinear optical imaging remains the premier technique for deep-tissue imaging in which typically a multi photon arrangement may be used to illuminate and excite a sample. However, the penetration depth, signal-to-noise ratio,...
Published: 7/25/2024   |   Inventor(s): Ronald Germain, Jianyong Tang, Hari Shroff, Yicong Wu
Keywords(s): AC3XXX, ADXXXX, IMAGING, MICRSCOPY, Multiview, NONLINEAR, optical, RESOLUTION
Category(s): Collaboration Sought > Licensing