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XR Platform for Personalized Neurological Rehabilitation and Diagnostics (Case No. 2025-99L)

Summary: UCLA researchers in the Department of Neurology have developed a novel AI-driven mixed reality headset for precision stroke rehabilitation. Background: Stroke is a leading cause of long-term motor disability, often requiring prolonged and intensive rehabilitation to restore motor function. Current methods for evaluating motor impairments...

Published: 7/21/2026 | Updated: 7/21/2026 | Inventor(s): Ahmet Arac, Nicolas Jeong Lee, John Krakauer

Keywords(s):

Category(s): Electrical, Electrical > Displays, Electrical > Visual Computing, Electrical > Visual Computing > AR/VR/Mixed Reality, Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Psychiatry And Mental Health

Next-Generation ROS Nanotherapy for Targeted Cancer Destruction

Produces complementary reactive oxygen species in tumors, enabling efficient tumor killing without external activation Background Conventional cancer treatments such as surgery, chemotherapy, and radiotherapy are often invasive, non-specific, and associated with systemic toxicity and long-term side effects. Emerging nanomedicine approaches improve...

Published: 5/8/2026 | Updated: 5/8/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Chao Wang

Keywords(s): breast cancer, chemodynamic therapy (CDT), Fenton reaction, ferrous, immuno-oncology, metal-organic framework (MOF), nanomedicine, oncology therapeutics, porphyrin, reactive oxygen species (ROS), Russell mechanism, solid tumor, tumor microenvironment, tumor suppression, tumor targeting, tumour microenvironment

Category(s): Therapeutics

Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia

Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo

Keywords(s): anti-inflammatory, Anti-inflammatory drugs, biodegradable, biodistribution, blood-brain barrier, brain delivery, brain inflammation, CNS drug delivery, cytokine expression, Drug Delivery, Drug Development, glutathione, immune cell, immunohistochemistry, irak4 inhibitor, lipopolysaccharides, microglia, mouse model, nanocarrier, nanocarriers, nanomedicine, neuroinflammation, pancreatic cancer, pharmaceuticals, pharmacokinetics, preservation, pro-inflammatory cytokine, small molecules, water-soluble, weight maintenance

Category(s): Therapeutics

Next-Generation Photothermal Nanoagent for Safe Systemic Tumor Ablation

A resonance energy transfer (RET)–engineered nanoplatform enabling complete tumor ablation using near-infrared irradiation Background Photothermal therapy (PTT) uses NIR light to generate localized tumor heating. However, many systems require elevated laser power densities to achieve therapeutic temperatures, limiting translational feasibility....

Published: 4/3/2026 | Updated: 4/3/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Prem Singh

Keywords(s):

Category(s): Therapeutics, Medical Devices

Self-Adjuvanting, Needle-Free Nanoparticle Vaccine Platform for Next-Generation Respiratory Vaccines

Description This technology is a functionalized graphene oxide nanoparticle platform designed to deliver protein antigens efficiently to the immune system, particularly through intranasal administration. When administered intranasally, antigen-loaded nanoparticles stimulate both mucosal and systemic immunity, closely mimicking natural infection while...

Published: 3/19/2026 | Updated: 3/19/2026 | Inventor(s): Baozhong Wang, Chunhong Dong

Keywords(s):

Category(s): Therapeutics

Anti-LILRB5 Monoclonal Antibodies for Therapeutic and Diagnostic Use

Tumor microenvironment (TME) plays a critical role in regulating immune responses to tumors. UTHealth Houston and UTSW researchers discovered certain membrane tyrosine kinase Eph receptors, including EphA7 and EphB1, specifically bind to the immune inhibitory receptors leukocyte Ig-like receptor family B 5 (LILRB5) and result in bi-directional signaling....