Search Results - therapeutics

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Self-Powered Electrical Stimulation Magnetoelastic Bandage for Accelerated Wound Healing (Case No. 2025-99N)
Reference: UCLA Case No. 2025-99N Please reach out to our office for more information.
Published: 9/12/2025   |   Inventor(s): Jun Chen, Kanishk Rai, Song Li, Il Woo Ock, Haochen Nan
Keywords(s):  
Category(s): Therapeutics, Therapeutics > Aesthetic Medicine, Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Flexible Electronics
Human antibodies targeting a novel flu epitope for use as a universal flu vaccine and treatment
Technology Summary: Scientists at Vanderbilt have discovered a new class of human antibodies specific to a novel target for the detection, prevention, and treatment of influenza A viruses (IAV). Using structural characterization, they have identified a novel antigenic site on the hemagglutin (HA) head domain that may be targeted by multiple antibodies...
Published: 8/28/2025   |   Inventor(s):  
Keywords(s): Infectious Disease
Category(s): Therapeutics, Vaccines
Targeting PD-1H to treat Acute Myeloid Leukemia (AML)
Summary Despite the success of immune checkpoint inhibitors (ICI) like anti-PD-1 in treating other cancers, these therapeutics have not been demonstrated to effectively treat acute myeloid leukemia (AML). Vanderbilt researchers have identified PD-1H as a potential target for treating AML, opening the door for effective therapy using an ICI molecule. Addressed...
Published: 8/28/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)
Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...
Published: 8/21/2025   |   Inventor(s): Wentai Liu
Keywords(s): algorithmic cancer detection, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, cancer inhibition, cancer metabolism, Cancer stem cells, cancer target, castration resistant prostate cancer, Chemotherapy, head and neck cancer, lympathic cancers, lymphatic cancer, Mesenchymal Stem Cell Derived Cancer Cells, Neuromodulation, non-small cell lung cancer, Orthotopic cancer models, Pancreatic cancer, prostate cancer, small cell cancer, small cell lung cancer, small cell prostate cancer
Category(s): Medical Devices, Medical Devices > Neural Stimulation, Chemical, Electrical, Therapeutics, Therapeutics > Oncology
A novel method to achieve polymeric nanoparticles loaded with peptide therapeutics, which display high encapsulation efficiency, low burst release, and long acting sustained release profiles
A novel method to achieve polymeric nanoparticles loaded with peptide therapeutics, which display high encapsulation efficiency, low burst release, and long acting sustained release profiles. Overview A major challenge in the field of peptide and protein therapeutics is effective administration and subsequent delivery to the site of action. Due to...
Published: 8/13/2025   |   Inventor(s): Edith Mathiowitz, Cameron Baptista
Keywords(s):  
Category(s): Therapeutics
A novel molecular target for the treatment of heart failure with preserved ejection fraction
Krüppel-like factor 4 regulates pressure-induced cardiac hypertrophy Overview Cardiac hypertrophy, a key risk factor for heart failure and sudden cardiac death, arises from hemodynamic and neurohormonal stress, often culminating in adverse remodeling. While much of the focus has been on activators of hypertrophic signaling, this technology identifies...
Published: 8/13/2025   |   Inventor(s): Mukesh Jain, Xudong Liao, Tapatee Das, Yosuke Nagai
Keywords(s):  
Category(s): Therapeutics
A photocrosslinkable bone derived biomaterial for tissue engineering applications
Summary Demineralized bone matrix has been widely used in the clinic to heal bone injuries due to its remarkable regenerative properties. However, this is not a material that can be synthesized in large batches, with highly reproducible chemistry, and cannot be set/polymerized in-situ for precise adaptation. BoneMA is photopolymerizable material that...
Published: 7/23/2025   |   Inventor(s): Luiz Bertassoni, Avathamsa Athirasala
Keywords(s):  
Category(s): Therapeutics, Device
Methods and Systems for Low-Cost Medical Image Annotation Using Non-experts (Case No. 2025-108)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an AI-based interface designed to enable individuals without specialized training to identify arthritis in medical imaging. Background: The use of artificial intelligence (AI) for medical imaging analysis holds great promise for the future of healthcare....
Published: 7/23/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang
Keywords(s): 3D tissue imaging, AI-guided diagnostics, AI-guided medical imaging, AI-guided medical intervention, arthritis, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, Artificial Neural Network, bioimaging, Computer-Aided Diagnosis, computer-aided radiology, Diagnostic Markers & Platforms, Diagnostic Test, diagnostics, generative artificial intelligence, Image Analysis, Image Resolution, Imaging, infrared thermal imaging, Machine Learning, machine learning modeling, machine perception, Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Pathology, Medical artificial intelligence (AI), Medical diagnostics, Medical Imaging, Microscopy And Imaging, non-invasive imaging, osteoarthritis, radial MRI, radiologic imaging, Radiology, Radiology / Radiomitigation, radiosurgery
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Radiology
Targeted Therapy for Inflammatory Diseases and Cancer
Description This technology is a biologic therapy that modulates macrophage activity to redirect immune responses, reduces inflammation, and suppresses tumor growth. Preclinical studies in mouse models show that treatment with this technology significantly reduces tumor burden, decreases metastasis spread, and reshapes the tumor microenvironment. These...
Published: 7/18/2025   |   Inventor(s): Zhi-Ren Liu, Guangda Peng
Keywords(s):  
Category(s): Therapeutics
Highly Effective Monoclonal Antibodies for Gonorrhea Treatment
Description This technology is a series of novel monoclonal antibodies (mAbs) developed to specifically block the growth of N. gonorrhoeae. In preclinical studies, select mAbs not only reduced clinical symptoms and bacterial load in mice but also conferred cross-protection against invasive Neisseria meningitidis (Nme) infection. These findings support...
Published: 7/18/2025   |   Inventor(s): Cynthia Cornelissen, Julie Stoudenmire-Saylor
Keywords(s):  
Category(s): Therapeutics
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