Search Results - therapeutics

511 Results

Sort By:

Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia

Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo

Keywords(s): Anti-inflammatory drugs, Drug Delivery

Category(s): Therapeutics

Linking the Gap Between Traumatic Brain Injuries & Cognitive Impairments Through the Creation of Machine Learning Based Diagnostic & Prognostic Clinic (Case No. 2026-251)

Summary: UCLA researchers have developed a machine learning-based clinical decision support tool that predicts patient-specific cognitive impairments following traumatic brain injury (TBI) using neuroimaging and multimodal clinical data. The software leverages MRI-derived structural brain information to generate individualized diagnostic and prognostic...

Published: 5/1/2026 | Updated: 4/30/2026 | Inventor(s): Sonya Ashikyan, Martin Monti, Jeffrey Chiang

Keywords(s):

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > MRI, Therapeutics > CNS and Neurology, Therapeutics

Active Electromagnetic Interference Suppression for Magnetic Resonance Imaging-Guided Interventions (Case No. 2026-217)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a software-based active electromagnetic interference suppression solution for real-time MRI-guided interventions. Background: Microwave ablation (MWA) has emerged as the preferred thermal ablation modality for treating non-surgical patients with primary and metastatic...

Published: 4/16/2026 | Updated: 4/14/2026 | Inventor(s): Holden Wu, Qing Dai

Keywords(s):

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Lab Equipment, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Mechanical, Mechanical > Instrumentation, Mechanical > Sensors, Electrical, Electrical > Electronics & Semiconductors, Electrical > Signal Processing, Electrical > Instrumentation, Electrical > Imaging

Next-Generation Photothermal Nanoagent for Safe Systemic Tumor Ablation

A resonance energy transfer (RET)–engineered nanoplatform enabling complete tumor ablation using near-infrared irradiation Background Photothermal therapy (PTT) uses NIR light to generate localized tumor heating. However, many systems require elevated laser power densities to achieve therapeutic temperatures, limiting translational feasibility....

Published: 4/3/2026 | Updated: 4/3/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Prem Singh

Keywords(s):

Category(s): Therapeutics, Medical Devices

Self-Adjuvanting, Needle-Free Nanoparticle Vaccine Platform for Next-Generation Respiratory Vaccines

Description This technology is a functionalized graphene oxide nanoparticle platform designed to deliver protein antigens efficiently to the immune system, particularly through intranasal administration. When administered intranasally, antigen-loaded nanoparticles stimulate both mucosal and systemic immunity, closely mimicking natural infection while...

Published: 3/19/2026 | Updated: 3/19/2026 | Inventor(s): Baozhong Wang, Chunhong Dong

Keywords(s):

Category(s): Therapeutics

Anti-LILRB5 Monoclonal Antibodies for Therapeutic and Diagnostic Use

Tumor microenvironment (TME) plays a critical role in regulating immune responses to tumors. UTHealth Houston and UTSW researchers discovered certain membrane tyrosine kinase Eph receptors, including EphA7 and EphB1, specifically bind to the immune inhibitory receptors leukocyte Ig-like receptor family B 5 (LILRB5) and result in bi-directional signaling....