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Search Results - diagnostic+markers+%26+platforms
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Swabseq Universal Pathogen Diagnostic Platform (Case No. 2026-121)
Summary: UCLA researchers in the Department of Computer Science have developed a next-generation universal pathogen diagnostic platform combining scalable genomic sequencing, simplified laboratory workflows, and integrated logistics infrastructure to enable rapid, low-cost, high-throughput infectious disease detection. Background: The rise of pathogen-specific...
Published: 6/5/2026
|
Updated: 6/5/2026
|
Inventor(s):
Eleazar Eskin
,
Valerie Arboleda
,
Chongyuan Luo
,
Taryn Jakub
,
Traci Toy
Keywords(s):
AI-guided diagnostics
,
Assay
,
Computer-Aided Diagnosis
,
COVID-19
,
Diagnostic Markers & Platforms
,
diagnostic platforms
,
Diagnostic Test
,
diagnostics
,
Infectious Diseases
,
Infrastructure
,
Medical diagnostics
,
metagenomic diagnostic platform
,
Pathogen
,
platform technology
,
scalable platform
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Infectious Diseases > COVID
,
Software & Algorithms > Digital Health
,
Software & Algorithms
,
Platforms > Diagnostic Platform Technologies
,
Platforms
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
Enzyme-Based Method for the Amplified Detection of Molecules on Particles (Case No. 2026-130)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel enzyme-based particle platform that enables amplified molecular detection in fully aqueous systems for sensitive, multiplexed analysis of low-abundance analytes. Background: The detection of molecules and determination of enzymatic activity are foundational across...
Published: 6/5/2026
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Updated: 6/5/2026
|
Inventor(s):
Alyssa Arnheim
,
Dino Di Carlo
Keywords(s):
Antibody
,
Aptamers
,
Assay
,
barcode
,
Biomarker
,
Biosensor
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Drug Discovery
,
ELISA
,
enzyme functionalization
,
Enzyme Substrate (Biology)
,
Flow Cytometry
,
Fluorescence
,
High-Throughput Screening
,
hydrogel
,
Immunoassay
,
Medical diagnostics
,
microparticles
,
Molecular Biology
,
multiplexed analysis
,
multiplexing
,
Nucleic Acids
,
protein
,
Signal-To-Noise Ratio
Category(s):
Diagnostic Markers > Targets And Assays
,
Diagnostic Markers
,
Platforms > Diagnostic Platform Technologies
,
Chemical > Chemical Sensors
,
Life Science Research Tools > Antibodies
Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)
UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...
Published: 9/11/2025
|
Updated: 9/11/2025
|
Inventor(s):
David Wong
,
Jordan Cheng
Keywords(s):
Cancer
,
cell-free DNA
,
circulating DNA
,
Diagnostic Markers & Platforms
,
DNA methylation
,
liquid biopsy
,
next generation sequencing (NGS)
Category(s):
Software & Algorithms > Bioinformatics
,
Life Science Research Tools > Research Methods
,
Platforms > Diagnostic Platform Technologies
Methods and Systems for Low-Cost Medical Image Annotation Using Non-experts (Case No. 2025-108)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an AI-based interface designed to enable individuals without specialized training to identify arthritis in medical imaging. Background: The use of artificial intelligence (AI) for medical imaging analysis holds great promise for the future of healthcare....
Published: 11/6/2025
|
Updated: 7/23/2025
|
Inventor(s):
Xiang Chen
,
Youngseung Jeon
,
Christopher Hwang
Keywords(s):
3D tissue imaging
,
AI-guided diagnostics
,
AI-guided medical imaging
,
AI-guided medical intervention
,
arthritis
,
Artifical Intelligence (Machine Learning, Data Mining)
,
Artificial Intelligence
,
artificial intelligence algorithms
,
artificial intelligence augmentation
,
artificial intelligence/machine learning models
,
Artificial Neural Network
,
bioimaging
,
Computer-Aided Diagnosis
,
computer-aided radiology
,
Diagnostic Markers & Platforms
,
Diagnostic Test
,
diagnostics
,
generative artificial intelligence
,
Image Analysis
,
Image Resolution
,
Imaging
,
infrared thermal imaging
,
Machine Learning
,
machine learning modeling
,
machine perception
,
Magnetic Resonance Imaging Medical Physics
,
Magnetic Resonance Imaging Pathology
,
Medical artificial intelligence (AI)
,
Medical diagnostics
,
Medical Imaging
,
Microscopy And Imaging
,
non-invasive imaging
,
osteoarthritis
,
radial MRI
,
radiologic imaging
,
Radiology
,
Radiology / Radiomitigation
,
radiosurgery
Category(s):
Software & Algorithms
,
Software & Algorithms > AI Algorithms
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > Digital Health
,
Software & Algorithms > Image Processing
,
Life Science Research Tools
,
Life Science Research Tools > Lab Equipment
,
Life Science Research Tools > Microscopy And Imaging
,
Medical Devices
,
Medical Devices > Medical Imaging
,
Medical Devices > Monitoring And Recording Systems
,
Therapeutics
,
Therapeutics > Musculoskeletal Disease
,
Therapeutics > Radiology
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....
Published: 2/14/2025
|
Updated: 4/1/2024
|
Inventor(s):
Aydogan Ozcan
,
Hyouarm Joung
,
Hyun-June Jang
,
Junhong Chen
Keywords(s):
Biomarker
,
biomarkers
,
Biomaterial
,
Biosensor
,
Computer-Aided Diagnosis
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Electrical
,
Electrical Engineering
,
electrically-mediated sensing
,
electrochemical sensors
,
enzyme functionalization
,
field-effect transistors (FETs)
,
Medical diagnostics
,
multiplexed analysis
,
Point Of Care
,
point-of-care
,
porous media
,
sample matrix effects
,
transistors
Category(s):
Electrical
,
Electrical > Sensors
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Platforms
,
Platforms > Diagnostic Platform Technologies
Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)
Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...
Published: 3/20/2025
|
Updated: 10/12/2023
|
Inventor(s):
Eleazar Eskin
,
Valerie Arboleda
Keywords(s):
agnostic detection
,
Bioinformatics
,
bioinformatics pipeline
,
Computer-Aided Diagnosis
,
Diagnostic Markers & Platforms
,
Diagnostic Test
,
DNA Sequencing
,
Medical diagnostics
,
metagenomic diagnostic platform
,
meta-genomics
,
next generation sequencing (NGS)
,
Pathogen
,
Pathogenesis
,
Sequencing
Category(s):
Platforms
,
Platforms > Diagnostic Platform Technologies
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Diagnostic Markers > Targets And Assays
,
Software & Algorithms
,
Software & Algorithms > Digital Health
,
Software & Algorithms > Bioinformatics
Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...
Published: 2/14/2025
|
Updated: 8/30/2023
|
Inventor(s):
Dino Di Carlo
,
Michael Bogumil
Keywords(s):
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Flow Cytometry
,
Medical diagnostics
Category(s):
Diagnostic Markers > Cancer
,
Diagnostic Markers > Targets And Assays
,
Chemical > Emulsions
,
Life Science Research Tools > Microfluidics And Mems
,
Life Science Research Tools > Research Methods
,
Platforms > Diagnostic Platform Technologies
Stain-Free, Rapid, and Quantitative Viral Plaque Assay Using Deep Learning and Holography (Case No. 2022-326)
Intro Sentence: UCLA researchers in the Department of Electrical and Computer Engineering have developed a rapid and stain-free quantitative assay using lens-free holography and deep learning to efficiently and cost-effectively determine the presence of viral plaque-forming units (PFUs) in samples. Background: A broad range of viruses have caused...
Published: 2/14/2025
|
Updated: 8/11/2023
|
Inventor(s):
Aydogan Ozcan
,
Yuzhu Li
,
Tairan Liu
Keywords(s):
Antiviral Drug
,
Artifical Intelligence (Machine Learning, Data Mining)
,
Assay
,
Bioassay
,
Computer Aided Learning
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Digital Holography
,
Electrical
,
Electrical Brain Stimulation
,
Electrical Breakdown
,
Electrical Engineering
,
Electrical Impedance
,
Electrical Load
,
Electrical Load Equation Of State
,
Electrical Resistance And Conductance
,
Electrical Resistivity And Conductivity
,
Holography
,
Immunoassay
,
Immunoassay Sense (Molecular Biology)
,
Lentivirus Viral Vector
,
Machine Learning
,
Machine Learning Autonomous Car Gradient Descent
,
Machine Learning Pain Management
,
Machine Learning Particulates Global Climate Model
,
Network Analysis (Electrical Circuits)
,
Perceptual Learning
,
Plasmid Trabecular Meshwork Aqueous Humour Viral Vector
,
Targets And Assays
,
Transcutaneous Electrical Nerve Stimulation
,
Transfection Viral Vector
,
Unsupervised Learning
,
Viability Assay
,
Viral Delivery Systems
,
Viral Envelope
,
Viral Load
Category(s):
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Electrical
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Life Science Research Tools > Other Reagents
,
Software & Algorithms > Artificial Intelligence & Machine Learning
2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule
SUMMARY: UCLA researchers in the Department of Chemistry and Biochemistry have designed and developed a protein cage which can be easily tailored to sense other proteins, opening in response, and thus delivering enclosed biological compounds across a wide variety of applications, including biosensing, molecular diagnostics, and targeted drug delivery....
Published: 9/12/2025
|
Updated: 10/31/2022
|
Inventor(s):
Todd Yeates
Keywords(s):
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Drug Delivery
Category(s):
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Nucleic Acid Platform Systems
,
Platforms > Drug Delivery > Nanoparticles
,
Platforms > Drug Delivery > Nucleic Acids
Robot-On-A-Dish: Automating Cellular Sorting and Analysis via Robotic Motor-Driven Flow (Case No. 2023-002)
Summary: UCLA researchers in the Department of Bioengineering have built a new cell sorting system that can handle and maintain linear flow control for a broad range of mesoscale particles in fluids. Background: The global market for drug discovery technologies was valued at $65.3 billion in 2019, and it is expected to grow at a CAGR of 9.6%....
Published: 2/14/2025
|
Updated: 10/26/2022
|
Inventor(s):
Dino Di Carlo
,
Reem Khojah
Keywords(s):
Cell Counting/Imaging
,
Content Analysis
,
Diagnostic Markers & Platforms
,
Drug Discovery
,
Flow Cytometry
,
Flow Device
,
High-Throughput Screening
,
mesoscale
,
mesoscale particles
,
Robotic liquid handling
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Chemical
,
Chemical > Instrumentation & Analysis
,
Life Science Research Tools > Lab Equipment
,
Life Science Research Tools > Cell Counting And Imaging
,
Life Science Research Tools > Microfluidics And Mems
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