Search Results - biocompatible

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Customized Telodendrimer Nanocarriers for Targeted Drug Delivery for Disease Treatments
A suite of nanocarrier technologies that provide targeted drug delivery of hydrophobic and hydrophilic drugs to specific disease sites. Background: Delivery of therapeutic and diagnostic compounds is limited by the lack of efficient carriers to improve in vivo stability, selectivity as well as to reduce immunogenicity. Conventional nanocarrier design...
Published: 9/24/2024   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, affinity alkylating agent, autoimmune, autoimmune disease, bioactivity, biocompatible, biomaterials, chemical formulation, chemistry, cisplatin, combintorial conjugated dendrimer, dendritic drug delivery, drug delivery component, drug formulation, Featured, graft rejection, hydrophilic drug, hydrophobic drug, immune modulating, immunogenicity inflammation, inflammatory, inflammatory, inflammatory, inflammatory, inflammatory response, inflammatory response, intracellular delivery, methotrexate, moieties, nanocarriers, nanomedicine, nanoparticle, nanoparticle drug delivery, nanoparticle-enhanced delivery, nanotherapy, polyethylene glycol, polymyxin, targeted biologics delivery, targeted delivery, targeted drug delivery, targeted therapeutic delivery, targeting drug, Technologies, therapeutic drug, topoisomerase, vitamin E
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing
Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...
Published: 7/19/2023   |   Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari
Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering
Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
Neurostimulation Device for the Treatment of Chronic Pain
Chronic pain is a common, complex, and distressing problem that afflicts more than 20 percent (50 million) of the population in the United States and more than 1.9 billion people worldwide. The condition arises from a series of events or injuries, including but not limited to traumatic injury, obesity, congenital disorders, nerve damage and sports injuries....
Published: 2/13/2024   |   Inventor(s): Xue Wei, Jeffrey Hettinger, Xiao Hu, Robert Hirsh
Keywords(s): Biocompatible, Inflammation, Neurostimulation, Pain, Polymers, Protein
Category(s): Human Health Care > Medical Devices
Orthopedic Implants that are Safely Absorbed after the Body has Healed
Promotes new bone and prevents stress shielding to speed recoveryThese nontoxic biomedical implants stabilize fractures or temporarily assist the healing of damaged bone. The body safely absorbs these devices once they are no longer needed. Composed of a magnesium alloy that contains calcium and strontium, these implants not only mimic natural bone's...
Published: 6/27/2021   |   Inventor(s): Benjamin Keselowsky, Michele Manuel, Harpreet Brar, Malisa Sarntinoranont, Ida Svensson Berglund
Keywords(s): Bioabsorbable, biocompatible, Composite, dissolution, Drug-eluting, Magnesium, Medical Device, Orthopedic, Strontium
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Medical Devices > Consumable
Total Energy Shaping for Task-Invariant Control of Lower-Limb Exoskeletons
We present a total energy shaping control methodology for the development of portable lower-limb assistive exoskeletons and orthotic devices that help reduce the human’s effort and augment natural motion. Current robotic exoskeletons restrict joint motion to pre-defined position trajectories during gait rehabilitation; such methods aim to replicate...
Published: 5/20/2020   |   Inventor(s): Robert Gregg, Ge Lv
Keywords(s): Biocompatible, Devices, Electronics, Engineering & Physical Sciences, Mechanical Systems, Medical Devices, Research Tools, Sensors & Controls, Signal Processing, Software, Therapeutics, Transportation, Wireless
Category(s): Robotics, Healthcare, Control Strategy
Amorphous Silicon Carbide Ultramicroelectrode Arrays for Neural Interfaces
The clinical ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response (FBR), which can lead to neuron damage and reduced reliability. Minimizing this tissue response is necessary for the development of implantable interfaces for studying neural...
Published: 4/26/2019   |   Inventor(s): Stuart Cogan, Timothy Gardner
Keywords(s): Biocompatible, Electronics, Engineering & Physical Sciences, Implantable, Life Sciences, Materials, Medical, Sensors & Controls, Therapeutics
Category(s): Research Tools, Devices, Healthcare
Neurocase: Peripheral Nerve Electrode for Neural Recording and Stimulation
The ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response, which can lead to neuron damage and reduced reliability of results. Minimizing such tissue responses is necessary to develop implantable interfaces for studying neural activity and even...
Published: 1/5/2022   |   Inventor(s): Stuart Cogan, Atefeh Ghazavi, Alexandra Joshi-Imre
Keywords(s): Biocompatible, Biotechnology, Electronics, Engineering & Physical Sciences, Healthcare, Implantable, Life Sciences, Materials, Medical, Medical Devices, Therapeutics
Category(s): Biomedical, Devices, Research Tools
Noninvasive & High-Contrast Imaging of Kidney Function Enabled by Renal Clearable Nanofluorophores
The University of Texas at Dallas is seeking companies interested in commercializing a renal-clearable contrast agent that is the first to enable high-resolution, noninvasive, fluorescent imaging of kidney function. Kidney disease affects more than 10% of adults worldwide and the current technologies used to detect and track the progress of renal complications...
Published: 4/26/2019   |   Inventor(s): Jie Zheng, Mengxiao Yu
Keywords(s): Biocompatible, Biomarkers, Chemistry, Diagnostics, Healthcare, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools
Category(s): Biomedical, Imaging
Small Molecule Inhibitor of Forkhead Box Protein C2 (FOXC2): Therapeutic Candidate and Diagnostic Tool for Metastatic Cancers
The transcription factor Forkhead Box Protein C2 (FOXC2) is known to be necessary to initiate and maintain the epithelial-mesenchymal transition (EMT), which has been a hot target for therapeutic intervention against cancers. The overexpression of FOXC2 bestows cancer cells with metastatic and cancer stem cell (CSC)‐like phenotypes, i.e., higher motility,...
Published: 4/26/2019   |   Inventor(s): Jiyong Lee, Maria Castaneda
Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Drug Delivery, Healthcare, Imaging, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools, Therapeutics
Category(s): Biomedical, Diagnostics
Compact System for Label-Free Analysis of Binding Kinetics for Multiple Analytes
There are numerous problems faced with many of the standard biomolecular analysis tools, such as limited sensitivity, expensive set-up and per-test necessities, and space requirements that have prohibited their use outside of a dedicated laboratory space. The need for a portable and inexpensive diagnostic tool that can be customized for various target...
Published: 6/26/2024   |   Inventor(s): Shalini Prasad, Anjan Panneer Selvam
Keywords(s): Biocompatible, Biomarkers, Devices, Electronics, Engineering & Physical Sciences, Healthcare, Life Sciences, Medical, Medical Devices, Molecular Biology
Category(s): Diagnostics
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