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Search Results - nanotechnology
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Netrin-1 mimetic peptide amphiphiles
Netrin-1 Mimetic Peptide Amphiphile Assemblies NU 2024-174 INVENTORS Samuel Stupp* Cara Smith Zaida Alvarez Pinto SHORT DESCRIPTION Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration. BACKGROUND Neurotrophic factors are essential for...
Published: 2/20/2026
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Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
CNS - Central Nervous System
,
CVA - Cerebrovascular Accident
,
Nanomaterials
,
Nanotechnology
,
Neurodegenerative disease
,
Regenerative medicine
,
SCI - Spinal cord injury
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Deuterized Low-K Dielectric Materials for TDDB Mitigation
Simple, scalable and inexpensive process to replace the hydrogen in low-k dielectrics with deuterium to improve semiconductor performance. Background: Low-k dielectrics are a class of materials used in the manufacture of nanoscale semiconductor devices. The problem with low-k dielectrics is that they are susceptible to a phenomenon known as time dependent...
Published: 1/30/2026
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Inventor(s):
James Lloyd
,
Patrick Lenahan
,
Niaz Mahmud
Keywords(s):
nanotechnology
,
semiconductors
Category(s):
Technology Classifications >
Nanotechnology
,
Campus > SUNY Polytechnic Institute
An Improved In Vivo Gene-Editing System Using Plug-and-Play Lipid Nanoparticles (LNPs) to Support CRISPR, Small Interfering RNA (siRNA), and Adenine Base Gene Editing Platforms
Simple, plug-and-play biodegradable lipids that form highly potent lipid nanoparticles (LNPs) for CRISPR mRNA delivery, outperforming benchmark gene-editing systems. Problem: CRISPR therapies can permanently correct disease-causing genes, but today's CRISPR delivery systems are either too risky or not potent enough. Viral vectors raise red flags...
Published: 1/14/2026
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Inventor(s):
Michael Mitchell
,
Xuexiang Han
,
Kelsey Swingle
,
Alex Hamilton
Keywords(s):
Bioengineering
,
Drug Delivery
,
Gene Editing
,
Gene Therapy
,
Nanotechnology
,
Platform Technology
,
Protein/Peptide (Non-Antibody)
,
Small Molecule
Category(s):
Technology Classifications > Therapeutics
,
Technology Classifications > Vaccines
,
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Materials
,
Technology Classifications > Research Tools & Reagents
A New Method for Dual Detection of Magnetic and Dielectric Signals from Core/Shell Nanoparticles for Advanced Biodetection and Diagnostics
Advantages Simultaneously detects magnetic and dielectric signals from core/shell nanoparticles with high sensitivity. Provides rapid, real-time biodetection in microfluidic systems using minimal sample volumes. Accurately differentiates healthy and cancer cells through enhanced signal responsiveness. Easily integrates into scalable biomedical...
Published: 12/1/2025
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Inventor(s):
Manh-Huong Phan
,
Kee Young Hwang
,
T. Lee
,
Minh Nguyen
,
Supawitch Hoijang
,
Dakota Brown
Keywords(s):
Biomarker
,
Nanotechnology
,
Sensors
Category(s):
Technology Classifications > Electronics >
Nanotechnology
Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090 INVENTORS Chad Mirkin (Northwestern University, Department of Chemistry)* Keith Brown Shu He Guoliang Liu Xing Liao Wooyoung Shim Abrin Schmucker SHORT DESCRIPTION This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks. BACKGROUND Current...
Published: 12/9/2025
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Inventor(s):
Keywords(s):
Lithography
,
Nanomaterials
,
Nanotechnology
,
Research tool
Category(s):
Life Sciences > Biomarkers & Biomedical Research Tools
Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169 INVENTORS Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for
Nanotechnology
(IIN)) Brian Meckes Wuliang Zhang SHORT DESCRIPTION For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Inventor(s):
Keywords(s):
Biologic
,
Biomarker
,
Biomedical
,
Cancer/Oncology
,
Chemicals
,
Diagnostics
,
Drug delivery
,
Nanoparticle
,
Nanotechnology
,
Personalized medicine
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
,
Life Sciences > Healthcare Devices, Tools & IT
,
Life Sciences > Biomarkers & Biomedical Research Tools
Video-Rate Infrared Focal Plane Array Based on Solution-Processed Black Phosphorus Films
NU 2025-012 INVENTORS Hooman Mohseni* Mark Hersam* Simone Bianconi Vinod Sangwan SHORT DESCRIPTION This innovation demonstrates a video-rate infrared focal plane array fabricated by integrating solution-processed black phosphorus films with modified CMOS read-out integrated circuits, enabling high-performance mid-infrared imaging. BACKGROUND Conventional...
Published: 11/6/2025
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Inventor(s):
Keywords(s):
Nanomaterials
,
Nanotechnology
Category(s):
Physical Sciences > Engineering & Technology
,
Physical Sciences > Materials and Industrial Processes
Structured Spiropyran Chelators for Rare Earth Element Separation Using Light (Case No. 2026-047)
Summary: UCLA researchers in the Department of Chemical & Biomolecular Engineering have developed structured spyropyran chelators that utilize light to selectively separate rare earth elements, offering an efficient approach to element recovery. Background: Rare earth elements (REEs) are essential materials that power modern technologies, from...
Published: 12/9/2025
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Inventor(s):
Aaron Moment
,
Andrew Grorud
,
Ah-Hyung Alissa Park
Keywords(s):
advanced materials processing
,
efficient separation
,
light-controlled chelation
,
metal deposition
,
metal nanocomposites
,
Metal process monitoring
,
Metalation
,
Metallurgy
,
Metal-Organic Framework
,
Metals
,
nanobody
,
Nanocomposites
,
Nanocrystal
,
Nanoelectronics
,
Nanotechnology
,
phase-transfer chelation
,
rare earth element separation
,
reversible ligand
,
selective metal binding
,
spiropyran-based chelator
,
stimuli-responsive ligand
,
structured ligand
,
sustainable rare earth recovery
,
targeted extraction
Category(s):
Materials
,
Materials > Metals
,
Materials > Functional Materials
,
Materials >
Nanotechnology
LNP + Squeeze: Enhancing Chimeric Antigen Receptor T-Cell Generation via Mechanoporation and Lipid Nanoparticles
Synergistic combination of mechanoporation and lipid nanoparticle (LNP) based transfection for an efficient, non-viral method of gene transfer to generate CAR-T cell therapies. Problem: Chimeric antigen receptor (CAR)-T cell therapy has transformed cancer treatment by engineering patients' T cells to precisely target and eradicate cancer cells....
Published: 8/28/2025
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Inventor(s):
Jina Ko
,
Jianhua Lim
Keywords(s):
Bioengineering
,
Cell Therapy
,
Gene Editing
,
Immunology
,
Immunoncology
,
Microfluidics
,
Nanotechnology
Category(s):
Technology Classifications > Research Tools & Reagents
,
Technology Classifications > Therapeutics
,
Technology Classifications > Chemical Processes and Synthesis
Using
Nanotechnology
to Target Aggressive Cancers
A modified gold nanoparticle is used to target aggressive triple negative breast cancer and melanoma by inhibiting RAD6 which is overexpressed in aggressive and chemo resistant cancers. Technology Summary This technology utilizes gold nanoparticles (GNPs) conjugated with a small molecule inhibitor (SMI#9) designed to target RAD6, a protein overexpressed...
Published: 9/26/2025
|
Inventor(s):
Malathy Shekhar
,
Guangzhao Mao
,
Yanhua Zhang
Keywords(s):
Breast Cancer
,
Driving Lifelong Health
,
Nanotechnology
Category(s):
Technology Category > Therapeutics
,
Technology Category > Oncology
,
Technology Category > Nanomaterials
,
Technology Category > Life Science
,
Technology Category > Drug Delivery
,
Technology Category > Cancer
,
Technology Category > Women's Health
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