Search Results - cholesterol

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2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing
Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...
Published: 7/19/2023   |   Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari
Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering
Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
A Method of Reducing Cholesterol Biosynthesis with Specific MicroRNAs
This technology is directed to the discovery of specific microRNAs that target and downregulate enzymes within the cholesterol biosynthetic pathway and is currently being tested in vivo. Briefly, microRNAs regulate the translation of messenger RNAs (mRNAs) into protein. The inventors have discovered a set of specific microRNAs that downregulate the...
Published: 4/8/2024   |   Inventor(s): Alan Remaley, Kasey Vickers
Keywords(s): BBXXXX, BIOSYNTHESIS, CHOLESTEROL, ICXXXX, IXXXXX, MicroRNAs, Novel, Patent Category - Biotechnology, REGULATE, STRATEGY
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, Application > Diagnostics, Application > Research Materials
PEGylated Bilirubin for the treatment of Hyperlipidemia, Obesity, and Type II Diabetes
Project ID: D2018-40 Background: Obesity, a low-grade inflammatory disease, has affected more than 150 million people in the US. Obesity and its associated risk factors are a prelude to the development of type II diabetes that accounts for a vast majority of the 25.8 million diabetes cases in the US. Bilirubin, a yellow pigment produced during...
Published: 5/9/2024   |   Inventor(s): Terry Hinds, David Stec
Keywords(s): Bilirubin, Brown Adipose Tissue, Cholesterol, Obesity, PEGylated, PPARα, Triglycerides, Type II Diabetes, White Adipose Tissue
Category(s): Cardiovascular, Renal, & Metabolism