Search Results - research+tools

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Novel Fabrication of an SLA 3D Printed Microfluidic Chip
Advantages Reversible compression sealing system enables reliable leak prevention without drilling through the chip Luer-compatible bracket design supports secure, standardized fluid connections up to high operating pressures Multi-layer architecture allows easy disassembly, cleaning, and repeated sterilization for cost-effective reuse Integrated...
Published: 2/13/2026   |   Inventor(s): Truman Roland, Ryan Fosnot, Randall Buck, Jade Houston
Keywords(s): Biotechnology, Cell & Tissue Culture & Engineering, Research Tools
Category(s): Technology Classifications > Medical > Medical Devices
Robotic Test Platform for Lower Extremity Prosthesis
Advantages Enables standardized testing for both above-knee and below-knee prostheses on a single platform Simulates real-world gait conditions, including multi-axis ankle motion and variable ground orientations Reduces reliance on amputee subjects during development, lowering cost and time Supports static, cyclic, and walking tests aligned with...
Published: 2/12/2026   |   Inventor(s): Serdar Kucuk, Redwan Alqasemi, Rajiv Dubey, Umut Mayetin
Keywords(s): Devices for Disabilities / Rehabilitation, Health Tech, Laboratory Devices, Medical Devices, Prosthetics, Research Tools, Robotics, Simulation Training Aid
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Medical Prosthetics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 11/12/2025   |   Inventor(s): Monika Raj
Keywords(s): Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Protein and Peptide Therapeutics, Research Tools
Category(s): TechPub Algolia > Therapeutics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 1/20/2026   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
A Novel Preclinical Model of Neonatal Necrotizing Enterocolitis
Advantages: Uniquely replicates the clinical scenario of RBC transfusion-exacerbated NEC in anemic neonates, providing a more accurate model than the traditional method Provide superior mechanistic insights, offering precise investigation of molecular pathways compared to in vitro intestinal injury assays Cost-effective and high-throughput experimentation,...
Published: 12/5/2025   |   Inventor(s): Akhil Maheshwari, Mohan Krishnan
Keywords(s): Animal Models, Research Tools
Category(s): Technology Classifications > Medical
Spine Simulator for Assessing Spinal Biomechanics
Advantages: Spine simulator helps assess the biomechanical effects of various interventions to the spine that include surgical implants, excision, or fusion, previously limited by range of motion Interventions for spinal injuries can be tested through highly customizable repeat simulations before and after various injuries / interventions Improved...
Published: 1/29/2026   |   Inventor(s): Nathan Schilaty
Keywords(s): Medical Devices, Research Tools, Surgical Tools
Category(s): Technology Classifications > Medical > Medical Devices
The Sudden Head Acceleration & Kinetic Encephalopathy (SHAKEn™) Device for Preclinical Modeling of Rotational Brain Injury
­Advantages: User control to adjust the positioning of the body plate (in the x/y plane) to optimize spinal alignment relative to the axis of rotation prior to insult. An aeronautics-grade angular rate sensor for direct measurement of angular velocity and to calculate rotational acceleration of the head. An electric plug to power accelerations...
Published: 7/18/2024   |   Inventor(s): Travis Jackson
Keywords(s): Animal Models, Lab Apparatus, Laboratory Devices, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience
A microcontroller for easier whole-cell patch clamping on dendrites and axons
Summary The current technology is a microcontroller that allows for the application of controlled negative pressure and simultaneous electrical impulses to make it easier to obtain whole-cell patch clamp recordings on small cellular structures. Technology Overview Whole-cell patch clamping is a technique commonly employed to study the electrical...
Published: 2/27/2025   |   Inventor(s): Stephen Smith, Timur Tsintsadze
Keywords(s): Research Tools, Research Tools - Other
Category(s): Research Tools
New Cancer Research Model: Spontaneously Transformed Mouse Epithelial Cancer Cell Lines
Abstract: The National Cancer Institute Cancer Genetics Branch is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize mouse epithelial cancer cell lines. Investigators at the NIH have created a collection of 45 mouse epithelial cancer cell lines derived from six...
Published: 8/19/2025   |   Inventor(s): Hesed Padilla-Nash, Karl Ried, Karen Hathcock, Nicole McNeil Ford
Keywords(s): Mouse Epithelial Cancer Cell Lines, Research Tools
Category(s): Application > Research Materials, TherapeuticArea > Oncology, Collaboration Sought > Licensing
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