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Novel Antifungal Agents with Dual Mechanism of Action

With a clear and growing unmet need, a novel mechanism of action, and demonstrated in vitro superiority over current standard-of-care agents, these novel boron-based antifungal agents represent a compelling early-stage opportunity with significant commercial and public health relevance. Background: Invasive fungal infections caused by opportunistic...

Published: 7/24/2026 | Updated: 7/24/2026 | Inventor(s): Bhaskar Das, Joshua Nosanchuk, Daniel Miranda

Keywords(s): Chemistry, Featured, Healthcare, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines

Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines

Luminous roof for NICU incubators for regulating circadian rhythms in infants and for providing high visibility of infant anatomy for healthcare staff

color: #f5f5f5; } RPI ID: 2014-057 Innovation Summary: A multipurpose lighting architecture integrates a flexible, sheet-based “illuminance blanket” embedded with distributed light sources and an intelligent controller capable of dynamically adjusting lighting parameters for neonatal incubators. The system delivers diffuse, shadow-free...

Published: 7/1/2026 | Updated: 7/1/2026 | Inventor(s): Mariana Figueiro, Jean Paul Freyssinier, Martin Overington, Mark Rea

Keywords(s): Biomedical Engineering, detector, Devices, Electrical Engineering, Electronics, health, healthcare, Mechanical Devices & Systems, medical, Medical Device\Diagnostic Systems, Parkinson's disease, quality of life, Sensors, Software, tremor, watch

Category(s): Biotechnology and the Life Sciences

BKHI Prototype

A survey instrument is a tool used to collect data and information from people, often through questionnaires or interviews. Background: Survey instruments are fundamental tools in the fields of social science, market research, public health, and education, among others. They enable researchers and organizations to systematically collect data on attitudes,...

Published: 6/12/2026 | Updated: 6/12/2026 | Inventor(s): Montgomery Douglas, Aimee Afable, Carla Boutin-Foster, Margaret Salisu, Mark Hoglund, Gwendolyn Lewis, Tenya Blackwell, Anthony DiVittis

Keywords(s): healthcare, Technologies

Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Computer Software, Technology Classifications > Data

Tibial Tubercle Osteotomy Fixation Device

Fixation device to secure bone fragment of tibial tuberosity to native bone after osteotomy surgical procedure. Background: Standard osteotomy techniques to join the tibial tubercle fragment to native bone include screw fixation alone or fixation with wire or suture, which are not reliable methods to holding the bone in place to avoid displacement...

Published: 5/13/2026 | Updated: 5/13/2026 | Inventor(s): Timothy Damron

Keywords(s): biomedical, biomedical engineering, hardware, healthcare, instrumentation, medical devices, medical equipment, orthopedics, osteoarthritis, surgery, suturing technique, Technologies

Category(s): Technology Classifications > Medical Devices, Campus > Upstate Medical University

Échafaudage super déformable inspiré de l'origami pour l'ostéogenèse par distraction

ORIGAMI INSPIRED FLAT-FOLDABLE SCAFFOLD (OIFFS) FOR DISTRACTION OSTEOGENESIS Innovative solution to accelerate bone healing after the distraction surgical process UNMET NEED Congenital limb asymmetry, complex long-bone fractures caused by accidents, and segmental bone loss following tumor resection are common clinical conditions that affect more...

Published: 7/3/2026 | Updated: 1/9/2026 | Inventor(s): Isabelle Villemure, Marie-Lyne Nault, Mohammad Ali Bagheri, Carl-Éric Aubin

Keywords(s): Healthcare, Innovation, Medical devices, Medical supplies, Medical technology

Category(s): Applications, English Applications > Health and care, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Secteurs, Secteurs > Sciences de la vie, Sectors > Life sciences, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Applications > Soins et santé > Traitement > Dispositifs médicaux, English Applications > Health and care > Treatment > Medical devices-T > Orthopedics-Md, Applications > Soins et santé, Applications > Soins et santé > Traitement > Dispositifs médicaux > Orthopédie

Method to Determine Quality of Mitochondrial Cargo in Extracellular Vesicles

A novel method that measures mitochondrial membrane potential in extracellular vesicles, providing a direct readout of mitochondrial quality and utility. Background: Studies have shown that EV-mediated intercellular communication is influenced, at least in part, by the mitochondrial cargo contained within EVs. This highlights the importance of rigorous...

Published: 6/19/2026 | Updated: 1/6/2026 | Inventor(s): Barbara Alevriadou, Zahid Manzar, Hans Minderman

Keywords(s): Biotechnology, Diagnostic, Healthcare, Pharmaceutical, Research Tool, Technologies, Therapeutic and Vaccines

Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

UNAFold® - Software suite for simulating and predictig nucleic acid folding, hybridization, and melting behavior

RPI ID: 2017-042 Innovation Summary: UNAFold® is a comprehensive software suite designed to simulate and predict nucleic acid folding, hybridization, and melting behavior using experimentally derived free energy parameters. It models secondary structures of single-stranded DNA or RNA, either individually or in pairs, under customizable temperature...

Published: 4/27/2026 | Updated: 12/22/2025 | Inventor(s): Nicholas Markham, Michael Zuker

Keywords(s): Bioinformatics, Biotechnology, Design, Diagnostics, discovery tool, DNA, healthcare, Human healthcare, modeling and simulation, molecular beacon, Molecular Biology, Molecular diagnostics, Nucleic acids, PCR primer, pharmaceutical, RNA, Software

Category(s): Biotechnology and the Life Sciences

Drill Guide/Suture Passer for Posterior Approach Total Hip Soft Tissue Repair

Combined drill guide and suture passer for use in assisting repair following posterior approach total hip arthroplasty. Background: The posterior approach to the hip for total hip replacement as well as trauma, pediatric orthopedic surgery, and tumors is the most common approach for total hip arthroplasties. However, the performance of this...

Published: 2/19/2026 | Updated: 5/13/2025 | Inventor(s): Timothy Damron

Keywords(s): biomedical engineering, biotechnology, hardware, healthcare, medical devices, medical equipment, orthopedics, surgery, suturing technique, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices

Novel Suturing Device Kit

A surgical "sewing machine" for rapid graft quilting and suturing in challenging spaces. Background: Grafts are commonly employed in urologic reconstructive surgery, but anchoring them in less accessible areas -- as in luminal stenosis surgery -- can be difficult. A novel surgical "sewing machine" capable of quilting and suturing...

Published: 5/28/2026 | Updated: 5/13/2025 | Inventor(s): Dmitriy Nikolavsky, Gennady Bratslavsky

Keywords(s): #SUNYresearch, barbed suture, healthcare, medical devices, surgery, suturing technique, Technologies

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare, Campus > Upstate Medical University

Liquid Tissue Graft

A minimally invasive option for treating urogenital stricture and other wounds using liquid buccal mucosa tissue graft. Background: There is no agreed upon optimal treatment for urogenital stricture disease, which occurs when inflammation or scar tissue narrows the ureter/urethra. Noninvasive options include: 1. using dilators of increasing size or...

Published: 1/30/2026 | Updated: 5/13/2025 | Inventor(s): Dmitriy Nikolavsky

Keywords(s): healthcare, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare

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