Search Results - cell+culture

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A New High-Throughput Cell Biology Method to Screen for Genes Critical for Cell Differentiation
A high-throughput method for identifying genes involved in the process of stem cell differentiation into specialized cells. Background: One of the many draws of stem cells is their potential for regenerating tissues, nerves, and other organs, but the differentiation potential of stem cells is highly regulated by genes. Therefore, the ability to...
Published: 7/11/2023   |   Inventor(s): Chunyu Liu
Keywords(s): cell culture, development, differentiation, high-throughput, neuroscience, regenerative medicine, screen
Category(s): Campus > Upstate Medical University, Technology Classifications > Gene Therapy
2022-067 Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a simple, innovative method for growing 3D cell cultures with improved organoid differentiation and reduced hypoxia-induced cell death. TITLE: Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues Background: 3D tissue culture,...
Published: 4/5/2024   |   Inventor(s): Neil Lin, Marie Payne
Keywords(s): 3D Printing, Biofilm, Biomaterial 3D Printing, Biomedical Engineering, Cancer, cancer detection, Cancer Immunotherapy, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, iPS/stem cells, Laminar flow, Microwell plates, organogenesis, Organoids, Personalized Pharmacotherapy, Pharmaceutical testing, Stem Cells / Regenerative Medicine, Tissue (Biology), tissue detection, Tissue Engineering, Tissue sedimentation
Category(s): Life Science Research Tools > Lab Equipment, Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > Oncology
2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing
Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...
Published: 7/19/2023   |   Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari
Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering
Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2021-285 Chemical Stimulation of Cellular Contractability to Enhance the Quality of Cultured Meat
Summary: UCLA researchers in the Department of Integrative Biology and Physiology have developed a novel methodology to improve the texture and overall quality of muscle grown ex vivo for sustainable biomanufacturing applications. Background: Livestock production is known to be ecologically expensive due to its use of large swaths of land and release...
Published: 7/19/2023   |   Inventor(s): Amy Rowat
Keywords(s): Beyond meat, biomanufacturing, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, Food Chain, meat, meat production, Sustainable nutrition
Category(s): Chemical, Therapeutics > Agtech And Animal Health
Differentiation of Olfactory Mucosa Derived Mesenchymal Stem Cells to Schwann Cells for Peripheral Nerve Repair
rder-collapse: collapse; } INV-21115 Background Peripheral nerve injuries resulting from trauma can be severe and permanently debilitating. Nerve autografting is the current gold standard for the treatment of such injuries. However, after grafting, in approximately one-third of cases, incomplete recovery with poor restoration of function is observed....
Published: 9/10/2024   |   Inventor(s): Ryan Koppes, Katelyn Neuman, Abigail Koppes, Aidan Kenny
Keywords(s): Biomedical implants, Cell Culture, Neurological Disease
Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering
2020-495 Well Plate and Petri Dish Fluid Exchange Plug
SUMMARY: UCLA researchers in the Department of Bioengineering developed an automated fluidic and gas exchange system that is compatible with commercially available petri dishes, well and multi-well plates. BACKGROUND: In vitro assays are typically performed on commercially available petri dishes or well plates. While users can manually modify a dish/well...
Published: 7/3/2024   |   Inventor(s): Peyton Tebon, Darin Williams
Keywords(s): Assay, Bioassay, biological assays, Cell Culture, cost-effective, fluidic exchange, gas exchange, Microwell plates, petri dish, sample environment, Targets And Assays
Category(s): Life Science Research Tools > Cell Lines, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Cell Counting And Imaging
Injectable Microengineered Tissues for Cardiac Regeneration
Each year, millions of patients, globally, suffer from heart failure and cardiovascular disease. Stem cell transplantation and tissue engineering strategies have tremendous potential for repair and/or regeneration of injured myocardium. The major hurdles in stem cell transplantation are poor cell survival, insufficient cardiogenic differentiation,...
Published: 2/23/2023   |   Inventor(s): Mehdi Nikkhah, Brent Vernon
Keywords(s): Biological Cell Manipulation, Cell Culture, MEMS, Tissue, Tissue Repair
Category(s): Life Science (All LS Techs), Biomaterials, Advanced Materials/Nanotechnology, Non-Cancer Therapeutics
Engineering Functional Groups into Electrospun Nanofibers for Cell Culture
Introduction Cell culturing is the process of growing cells in an artificial environment under controlled conditions in an effort to cause the cells to behave as they would in vivo. This is difficult to achieve because, in addition to the conditions such as temperature, pH, and gas concentrations, nutrients and energy requirements must be supplied...
Published: 6/22/2023   |   Inventor(s): Melvin Schindler, Hoo Chung
Keywords(s): Cell Culture, Cell Culture Additives, Nanofibrillar Surfaces, Sythetic Extracellular Matrix
Category(s): Biotechnology, Pharmaceutical, Test and Measurement