Search Results - cancer

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Bruton's Tyrosine Kinase as Anti-Cancer Drug Target

This technology identifies Bruton's Tyrosine Kinase (BTK) as a novel target in breast cancer therapy and provides methods for treatment and diagnosis by inhibiting a specific BTK variant. Background: Protein tyrosine kinases (PTKs) are essential enzymes involved in cellular communication and regulation, often playing a significant role in cancer...

Published: 5/5/2026 | Updated: 5/4/2026 | Inventor(s): Douglas Conklin, Antonis Kourtidis, Cheryl Eifert

Keywords(s): breast cancer, cancer, TAF, Technologies, therapeutic targets

Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany

Method and Apparatus for Implantable Tumor-Treating Field via Shape-Engineered Ultrasonic Powering Receiver

Advantages Enables battery-free, implantable tumor-treating field delivery directly at the tumor site Eliminates skull attenuation and cerebrospinal fluid shunting that limit conventional scalp-based TTF systems Fourfold higher ultrasonic-to-electric power conversion compared to standard cubic receivers Closed-loop field control maintains stable,...

Published: 5/5/2026 | Updated: 3/13/2026 | Inventor(s): Albert Kim, Sophia Selvarajan, Zeng-jie Yang, Silvia Valdes Rives

Keywords(s): Biotechnology, Cancer, Medical Devices, Medical Implants

Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Cancer, Technology Classifications > Energy & Environment > Energy Engineering

Dual Inhibition of RNA Polymerase I and III as a Novel Strategy for Targeting Ribosome Biogenesis in Cancer

A specially designed peptide blocks two key enzymes needed for ribosome production in cancer cells, shutting down their protein-making machinery and offering a new, more effective way to treat cancer and prevent drug resistance. Background: Ribosome biogenesis is a fundamental cellular process involving the coordinated synthesis of ribosomal RNA...

Published: 3/26/2026 | Updated: 2/19/2026 | Inventor(s): Haleigh Pascual, Bruce Knutson

Keywords(s): cancer, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines

HistoTME: an AI tool for prediction of the tumor microenvironment molecular composition from histopathology images

HistoTME is an AI software that predicts the tumor microenvironment’s molecular makeup from standard pathology images, helping identify lung cancer patients likely to benefit from immunotherapy without needing costly molecular tests. Background: The tumor microenvironment (TME) plays a crucial role in the progression and treatment response...

Published: 4/2/2026 | Updated: 2/3/2026 | Inventor(s): Tamara Jamaspishvili, Sushant Patkar, Alex Chen, Stephanie Harmon, Ismail Turkbey

Keywords(s): artificial intelligence, cancer, computational biology, digital image processing, disease diagnosis, Technologies

Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Medical Imaging

Profiling Chemically Modified DNA/RNA Units for Disease and Cancer Diagnosis

Diagnose a wide variety of conditions by analyzing DNA and RNA nucleotides/nucleosides. Background: In theory, RNA and DNA can be used to diagnose a broad range of diseases. Unfortunately, there are no existing technologies capable of providing comprehensive profiles of variant DNA/RNA components. Established approaches for the analysis/detection of...

Published: 1/30/2026 | Updated: 10/24/2025 | Inventor(s): Daniele Fabris, Rebecca Rose

Keywords(s): cancer, DNA modifications, epigenetics, genome-wide analysis, infection, oncology, RNA modifications, Technologies

Category(s): Technology Classifications > Diagnostics, Campus > University at Albany

OPTIMIZING CANCER CHEMOTHERAPY WITH THE GUT MICROBIOME

Researchers at UCSF have developed a novel innovation in harnessing the gut microbiome to alleviate severe side effects of chemotherapy. Dose-limiting toxicities remain a significant barrier in the advancement of drug therapies, particularly in oncology. Although decades of pharmacogenomic research have identified specific human genetic variants that...

Published: 4/15/2026 | Updated: 10/23/2025 | Inventor(s): Peter Turnbaugh, Chloe Atreya, Kidder Wesley, Kai Trepka

Keywords(s): Cancer, Diagnostics, Therapeutic

Category(s): Technology Classifications > Biology

METHODS, COMPOSITIONS, AND SYSTEMS TO DETECT NON-SMALL CELL LUNG CANCER

Researchers at CZ Biohub SF and UCSF have developed novel methods for the early detection of non-small cell lung cancer. Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in the U.S., with many cases diagnosed at an advanced stage, significantly reducing survival rates. Although low-dose chest CT (LDCT) scans are effective...

Published: 4/15/2026 | Updated: 10/23/2025 | Inventor(s): Chukwuka Didigu, Joseph DeRisi, David Jablons, Johannes Kratz, Andrew Kung

Keywords(s): Cancer, Diagnosis

Category(s): Technology Classifications > Biology

Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)

UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...

Published: 9/11/2025 | Updated: 9/11/2025 | Inventor(s): David Wong, Jordan Cheng

Keywords(s): Cancer, cell-free DNA, circulating DNA, Diagnostic Markers & Platforms, DNA methylation, liquid biopsy, next generation sequencing (NGS)

Category(s): Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)

Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...

Published: 4/29/2026 | Updated: 8/21/2025 | Inventor(s): Wentai Liu

Keywords(s): algorithmic cancer detection, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, cancer inhibition, cancer metabolism, Cancer stem cells, cancer target, castration resistant prostate cancer, Chemotherapy, head and neck cancer, lympathic cancers, lymphatic cancer, Mesenchymal Stem Cell Derived Cancer Cells, Neuromodulation, non-small cell lung cancer, Orthotopic cancer models, Pancreatic cancer, prostate cancer, small cell cancer, small cell lung cancer, small cell prostate cancer

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Chemical, Electrical, Therapeutics, Therapeutics > Oncology

Pericellular oxygen-controlling cell culture incubator

Incubator system that directly measures and controls pericellular oxygen levels enabling precise regulation of the cellular microenvironment Background: Cell culture is a fundamental technique in biomedical research that aims to replicate physiological conditions for cellular studies. While oxygen is a critical factor affecting cell behaviour and...

Published: 1/7/2026 | Updated: 6/13/2025 | Inventor(s): Sidi Bencherif, Thibault Colombani, Zachary Rogers

Keywords(s): biomedical research, Cancer, Cell Culture, Hypoxia

Category(s): Technology Classifications > 1. Life Science > Bio-sensors

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