Search Results - nanomedicine

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Customized Telodendrimer Nanocarriers for Targeted Drug Delivery for Disease Treatments
A suite of nanocarrier technologies that provide targeted drug delivery of hydrophobic and hydrophilic drugs to specific disease sites. Background: Delivery of therapeutic and diagnostic compounds is limited by the lack of efficient carriers to improve in vivo stability, selectivity as well as to reduce immunogenicity. Conventional nanocarrier design...
Published: 9/24/2024   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, affinity alkylating agent, autoimmune, autoimmune disease, bioactivity, biocompatible, biomaterials, chemical formulation, chemistry, cisplatin, combintorial conjugated dendrimer, dendritic drug delivery, drug delivery component, drug formulation, Featured, graft rejection, hydrophilic drug, hydrophobic drug, immune modulating, immunogenicity inflammation, inflammatory, inflammatory, inflammatory, inflammatory, inflammatory response, inflammatory response, intracellular delivery, methotrexate, moieties, nanocarriers, nanomedicine, nanoparticle, nanoparticle drug delivery, nanoparticle-enhanced delivery, nanotherapy, polyethylene glycol, polymyxin, targeted biologics delivery, targeted delivery, targeted drug delivery, targeted therapeutic delivery, targeting drug, Technologies, therapeutic drug, topoisomerase, vitamin E
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Nanopreparation for Co-Delivery of Drugs and siRNA
INV-13004 Background Overexpression of p‑glycoprotein (encoded by MDR1 gene) is often associated with multidrug-resistant cancer. This protein leads to drug resistance by the efflux of chemotherapeutic drugs from the cancerous cells. Small interfering RNA (siRNA), also known as post-transcriptional gene silencer, can suppress the expression of specific...
Published: 9/10/2024   |   Inventor(s): Vladimir Torchilin, Swati Biswas
Keywords(s): Delivery, Drug Delivery, Healthcare Innovation, Medical, Nanomedicine, Nanotechnology, Pharmaceutical Composition, Therapeutic
Category(s): -Nanotechnology, -Nanomedicine, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery
Nanococktail for combination therapy, compositions, methods, and uses
INV-20007 Background It is difficult to achieve optimal exposure of all agents in combination therapy with drugs that exhibit different properties. Nanoparticle delivery systems are a well-known means to modify the pharmacokinetics and distribution of drugs. Northeastern researchers have demonstrated that through nanoencapsulation, similar pharmacokinetic...
Published: 9/10/2024   |   Inventor(s): Srinivas Sridhar, Paige Baldwin, Bijay Singh
Keywords(s): Combination therapy, Drug Delivery, Nanomedicine, Therapeutic, Treatment
Category(s): -Nanotechnology, -Materials
Man 1-2 Man-PEGylated Derivative as a Tool for in vitro and in vivo Dendritic Cell Targeting
INV-1151 Background The immune system (IS) has a delicate equilibrium between its cells. The most important cells of the IS are the B lymphocytes (BL), macrophages (MO), and dendritic cells (DC), so-called antigen presenting cells (APC). They are the key-linkers between the innate and the adaptive immunity, which is a crucial factor that will lead...
Published: 9/10/2024   |   Inventor(s): Vladimir Torchilin, Tatiana Levchenko, Juan Pappalardo, Stefano Salmaso, Micaela Toniutti
Keywords(s): Cancer, Chemistry, COVID, Drug Delivery, Genome, Health, Healthcare Innovation, Medical, Nanomedicine, Research Tool
Category(s): -Health, -Nanomedicine, -Cancer, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery
Macrophage-Targeted Multi-Compartmental Delivery Systems
INV-1028 Background Macrophages are important immune cells in the body that regulate different biological processes involved in inflammatory and infectious diseases. Macrophages originate from the mononuclear phagocyte system (MPS) in the bone marrow. The MPS system comprises of monocytes and tissue, it matures into a larger phagocytic cell called...
Published: 9/10/2024   |   Inventor(s): Mansoor Amiji, Husain Attarwala, Shardool Jain, Mayur Kalariya
Keywords(s): Biotech, Breast Cancer, Cancer, Chemotherapy, Drug Delivery, Drugs, Health, Medical, Nanomedicine
Category(s): -Biomedical Materials, -Health, -Nanomedicine, -Cancer, Technology Classifications > 1. Life Science > Drug Delivery