Search Results - diagnostics

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Quantitative rapid diagnostic platform using porous silicon on paper
Summary While medical diagnostics today typically tradeoff between speed and sensitivity, Vanderbilt researchers have developed a diagnostic platform that is both rapid and quantitative by coupling lateral flow paper-based tests with color changing porous silicon membranes. This platform can be adapted to detect a wide range of biological and chemical...
Published: 9/19/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Diagnostics
LARGE-SCALE WIRELESS BIOSENSOR NETWORKS FOR BIOMEDICAL DIAGNOSTICS
Overview Electronic sensors are increasingly prevalent in the world around us. Scalability, however, is complicated by the fact that the signals at each sensor location can vary both in time and in magnitude, but often must be read at once by a single transceiver. Current brain-computer interface research, as an example, is hampered by inefficiencies...
Published: 8/22/2024   |   Inventor(s): Arto Nurmikko, Jihun Lee, Farah Laiwalla
Keywords(s):  
Category(s): Diagnostics
Machine-learning based forecasting of visual field deficits for glaucoma management
Summary The current technology is a machine learning algorithm that can accurately forecast glaucoma-induced visual field deficits and outperforms existing forecasting methods. This technology could allow for more efficient management of glaucoma by reducing the number of office-based visual field assessments. Technology Overview Glaucoma is characterized...
Published: 8/15/2024   |   Inventor(s): Ashkan Abbasi, Hiroshi Ishikawa, Sowjanya Gowrisankaran, Xubo Song, Bhavna Antony, Gadi (Chaim) Wollstein, Joel Schuman
Keywords(s): Diagnostics, Diagnostics - Other, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Software
Protease Activity Sensing Probes For Early Detection and Prognosis of Pancreatic Cancer
Summary The current technology is a liquid biopsy diagnostic screen for pancreatic ductal adenocarcinoma (PDAC), which is high throughput, requires very small blood volumes and has been validated in a large patient dataset. Technology Overview Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers and is typically discovered by accident...
Published: 7/31/2024   |   Inventor(s): Jared Fischer, Jose Luis Montoya Mira
Keywords(s): Diagnostics, Diagnostics - Cancer
Category(s): Diagnostics
5th Amendment to A Radio-Frequency-Free Hybrid Electrostatic/ Magnetostatic Cell for Transporting, Trapping, and Dissociating Ions in Mass Spectrometers - Internal Electron Source Configurations
Background The need to identify complex molecules in real-world samples has propelled mass spectrometry into a $3 billion industry growing 8% annually. The fragmentation of molecules within a mass spectrometer is necessary to accurately reveal their identity. The current approach uses a sledgehammer that complicates identification. Our technology...
Published: 6/17/2024   |   Inventor(s): Joseph Beckman, Valery Voinov, Douglas Barofsky
Keywords(s):  
Category(s): Diagnostics
Two Compartment Model for Detecting the Toxicity of Liver Metabolites
Overview Liver toxicity is a significant reason many new drugs fail in clinical trials. Primary human hepatocytes (PHHs) are the current gold standard for in vitro liver models; however, they have a number of limitations. We have invented an easy-to-use two-compartment device that provides in vitro 3D high-throughput prediction for safety assessments...
Published: 5/20/2024   |   Inventor(s): Kim Boekelheide, Jeffrey Morgan, Blanche Ip, Susan Hall, Hui Li
Keywords(s):  
Category(s): Diagnostics
Sealable Microvalve That Can Be Repeatedly Opened and Sealed
ink;color: #0000FF;text-decoration: underline; } INV-1243 Background The typical structure for a MEMS microvalve includes an orifice and a moveable plate that can be actuated to press against the orifice. When the plate does not press against the orifice, fluid can flow through the orifice and therefore through the valve. When the plate is pressed...
Published: 9/10/2024   |   Inventor(s): Carol Livermore, Chenye Yang
Keywords(s): Chemistry, Diagnostics, Environment, Homeland Security, Sensor Technology
Category(s): -Chemistry, -Equipment, -Homeland Security, -Sensors tech, -Health, Diagnostics, Technology Classifications > 2. Physical Science > Environmental/Clean tech, Technology Classifications > 2. Physical Science > Lab tech/equipment
Monoclonal Antibodies Against PCDH7 for Therapeutic and Diagnostic Use
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-associated deaths worldwide. UTHealth researchers discovered that the cell surface protein Protocadherin 7 (PCDH7) is highly expressed in NSCLC and promotes lung cancer development. Inventors at UTH in collaboration with Dr. O’Donnell’s group at UTSW have discovered a panel...
Published: 5/28/2024   |   Inventor(s): Zhiqiang An, Ningyan Zhang, Kathryn O'Donnell
Keywords(s):  
Category(s): Diagnostics, Oncology, Therapeutics, Biologics
RNA Biomarkers for Mild Traumatic Brain Injuries
With generous support from Riddell, TGen has developed a noninvasive diagnostic method for mild traumatic brain injury (mTBI) using advanced genomic analyses of circulating DNA and extracellular RNA (exRNA) existing in bodily fluids that can be easily sampled in the field such as blood, urine, and salvia, and bodily fluids that can be further sampled...
Published: 6/24/2024   |   Inventor(s): Kendall Van-Keuren Jensen, Matt Huentelman, Ashish Yeri
Keywords(s):  
Category(s): Diagnostics
CD74 as a biomarker and therapeutic target for familial platelet (FPD) disorder
Summary Research at OHSU has identified the CD74 signaling cascade as a potential therapeutic target and diagnostic biomarker for RUNX1-mutated familial platelet disorder (FPD), which is a premalignant condition for acute myeloid leukemia. Technology Overview Current estimates suggest as many as 18,000 people may be living with RUNX1-FPD in the United...
Published: 2/27/2024   |   Inventor(s): Anupriya Agarwal, Mona Mohammadhosseini
Keywords(s): Diagnostics, Diagnostics - Cancer, Diagnostics - Other, Therapeutics, Therapeutics - Cancer, Therapeutics - Other
Category(s): Diagnostics, Therapeutics
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