Search Results - technologies

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Generation of a single-chain recombinant IgA1 isotype antibody compatible with in vivo nucleic acid delivery for the treatment and prevention of flavivirus infection
This technology uses a single-chain IgA1 antibody delivered by DNA or RNA to enable the body to produce its own protection against dengue and Zika viruses, offering rapid, safe, and scalable prevention and treatment without risk of antibody-dependent enhancement. Background: Flavivirus infections, including those caused by dengue and Zika viruses,...
Published: 2/6/2026   |   Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): antibody therapy, infectious diseases, nucleic acid, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
Use of recombinant IgA1 isotype mAbs to prevent and antagonize transplacental transmission of flaviviruses in pregnant women
This technology is a single-chain IgA1 antibody delivered by DNA or RNA, enabling the body to produce its own dengue-neutralizing antibodies safely and quickly, without the risk of worsening infection, for rapid prevention and treatment of flavivirus diseases. Background: The field of flavivirus therapeutics, particularly for diseases like dengue,...
Published: 2/6/2026   |   Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): infectious diseases, monoclonal antibodies, pregnancy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
DEVICE FOR ORAL FLUID COLLECTION CONSISTING OF ABSORBANT MATERIAL AND NESTED TUBES REQUIRING CENTRIFUGATION
This is a simple, low-cost device using absorbent material and nested tubes to collect clean, mucous-free oral fluid samples by centrifugation, making sample collection easier, more hygienic, and affordable for labs and research. Background: Oral fluid collection is an essential process in various fields, including clinical diagnostics, biomedical...
Published: 2/6/2026   |   Inventor(s): Aaron Glass
Keywords(s): saliva, Salivary biomarkers, specimen collection, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics
Targeted Immune-Activating Antibody Conjugates for Cancer and Infectious Disease Therapy
This technology enables precise activation of the immune system by delivering potent TLR7/8 agonists directly to diseased cells. By combining immune stimulators with antibody targeting, it enhances therapeutic impact while minimizing systemic side effects. The approach offers a safer and more effective way to treat cancer and infectious diseases by...
Published: 2/3/2026   |   Inventor(s): Lawrence Tumey, Emmanuel Olawode
Keywords(s): Technologies, XCEED
Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering
HistoTME: an AI tool for prediction of the tumor microenvironment molecular composition from histopathology images
HistoTME is an AI software that predicts the tumor microenvironment’s molecular makeup from standard pathology images, helping identify lung cancer patients likely to benefit from immunotherapy without needing costly molecular tests. Background: The tumor microenvironment (TME) plays a crucial role in the progression and treatment response...
Published: 2/3/2026   |   Inventor(s): Tamara Jamaspishvili, Sushant Patkar, Alex Chen, Stephanie Harmon, Ismail Turkbey
Keywords(s): artificial intelligence, cancer, computational biology, digital image processing, disease diagnosis, Technologies
Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Medical Imaging
Contact Lens Design
This technology is a novel specialty soft contact lens that helps align the eyes in children with intermittent exotropia type strabismus, while preventing any adverse myopia progression, offering both vision correction and cosmetic improvement without worsening nearsightedness. Background: Strabismus, particularly exotropia, is a condition characterized...
Published: 1/29/2026   |   Inventor(s): Zi Rui Li
Keywords(s): Technologies
Category(s): Campus > SUNY College of Optometry, Technology Classifications > Healthcare
Designable Polymer Substrates for Correlative Light and Electron Microscopy
This technology uses customizable, transparent polymer substrates with precise pores and indexing patterns to facilitate correlative light and electron microscopy, enabling accurate correlation of live cell fluorescence imaging with ultrastructural details of sectioned cells on permeable supports for advanced biological research. Background: Correlative...
Published: 1/29/2026   |   Inventor(s): Haixin Sui, Yubing Xie, Dipayan Sarkar, Adam Koplas, Julia Garrison, Natalya Tokranova, Yanfeng Zhang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Imaging, Technology Classifications > Medical Imaging
Novel three-dimensional, conformal microelectrode arrays for interrogating and manipulating three-dimensional cell culture systems
A flexible, biocompatible microelectrode array wraps around 3D cell cultures such as organoids, enabling comprehensive electrical recording and stimulation for advanced research, drug testing, and personalized medicine, overcoming the limitations of traditional flat electrode arrays. Background: Three-dimensional (3D) cell culture systems, such as...
Published: 1/29/2026   |   Inventor(s): Susan Sharfstein, Nathaniel Cady, Yubing Xie, Natalya Tokranova, Anthony Manning, Fernando Pesantez Torres
Keywords(s): 3D culture, 3D flexible microelectrode, electrophysiology, microelectrode array, microfabrication, neurodegeneration, organoid, polymer materials, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
Pharmacological strategy to treat hydrocephalus
This technology offers a non-surgical treatment for hydrocephalus by using drugs to enhance the removal of harmful macromolecules from the brain’s ventricles, targeting specific cellular transport mechanisms to reduce fluid buildup and disease progression. Background: Hydrocephalus is a neurological disorder characterized by the abnormal accumulation...
Published: 1/29/2026   |   Inventor(s): Satish Krishnamurthy, David Lehmann
Keywords(s): hydrocephalus, pharmacology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
Polyphasic Ultrasonic Power transfer for wireless charging of implants.
This technology uses multiple piezoelectric transducers with controlled phase shifts to create engineered ultrasonic waves, enabling efficient, wireless power transfer through tissue to implanted medical devices or sensors, overcoming limitations of traditional electromagnetic intra-body power transfer systems. Background: Wireless power transfer...
Published: 1/29/2026   |   Inventor(s): Amit Sangwan, Dante Riccoboni
Keywords(s): bioelectronics, biomedical engineering, biotechnology, Medical Device, Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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