Search Results - technologies

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Netrin-4–Mediated Disruption of Basement Membranes for Targeted Therapeutic Delivery
Novel tools that promote the delivery of therapeutics to treat inner retinal diseases such as diabetic retinopathy, retinal vein occlusion, and retinitis pigmentosa. Background: Non-surgical access to tissues for direct biological manipulation, e.g. gene transfer, stem cell transplantation, and drug delivery, can be difficult because many tissues...
Published: 3/3/2026   |   Inventor(s): Dale Hunter, William Brunken, Peter Yurchenco, Karen Mckee
Keywords(s): biologic therapies, drug delivery component, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines
Site-Specific Synthesis of 2D TMDs for High-Performance Nanoelectronic Devices
A lithographically defined, transfer-free CVD process enables site-specific growth of MoS₂ directly on CMOS-compatible SiO₂/Si substrates using patterned MoO₃ as both precursor and high-k dielectric. The approach delivers tunable crystallinity, improved interface quality, and enhanced FET performance while eliminating post-growth transfer and etching...
Published: 3/3/2026   |   Inventor(s): Huamin Li, Fei Yao, Gabriel Lee, Keith Wong, Ajay Yadav, Chu-Te Chen, Anthony Cabanillas
Keywords(s): Materials & Chemicals, Semiconductor and Microprocessing, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Electronics, Technology Classifications > Nanotechnology, Technology Classifications > Materials and Chemicals
Modular Hybrid Simulator (Endovascular Flow model with embedded sensors for operative feedback) powered by 3D auto segmentation software for Endovascular Modeling and Flow Model additions.
The Modular Hybrid Simulator is an advanced training platform for endovascular procedures, combining patient-specific 3D modeling with real-time operative feedback to enhance learning and procedural planning. Background: Endovascular training currently faces challenges such as inconsistent learning curves among trainees and the limitations of existing...
Published: 3/3/2026   |   Inventor(s): Hesham Masoud
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Ultrasonic Transmission System with Modular Cavitation-Enhancing Wire
This device uses ultrasonic vibrations delivered through a specialized wire to safely and efficiently clear blockages or remove implants from medical tubes, offering a non-invasive, customizable solution for maintaining and treating tube obstructions in healthcare settings. Background: Nephrostomy tubes and other indwelling medical devices are critical...
Published: 3/3/2026   |   Inventor(s): Alexander Collins, Scott Wiener
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Methods and Apparatus to Allocate Physical Qubits to Support Distributed Quantum Error Correction (QEC) Codes
A novel distributed quantum computing system and several methods of qubit allocation to enhance scalability to achieve large-scale fault-tolerant Quantum Systems. Background: Quantum Processing Units (QPUs) are specialized components of Quantum Computing systems which leverage the principles of quantum mechanics to perform complex calculations. Current...
Published: 3/3/2026   |   Inventor(s): Chunming Qiao, Shahram Babaie
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Quantum Computing, Technology Classifications > Computers
Targeting RNA Polymerase I Protein–Protein Interfaces Using Peptide Inhibitors: A Computational Strategy Powered by PepTelligence, a Comprehensive Peptide Scoring System
PepTelligence is an innovative computational tool designed to evaluate and optimize therapeutic peptides by integrating multiple biochemical and pharmacological factors into a unified scoring system. Background: The development of PepTelligence addresses a significant challenge in peptide drug discovery: the absence of a comprehensive evaluation...
Published: 2/25/2026   |   Inventor(s): Maryam Kabiri, Bruce Knutson
Keywords(s): multi-parameter scoring, peptide design, peptide drug discovery, peptide scoring system, structural bioinformatics, Technologies, therapeutic peptides
Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Ambient-Temperature Direct Air Capture of Carbon Dioxide
Novel amine-based sorbents for carbon dioxide capture with enhanced oxidative and thermal stability BACKGROUND: Anthropogenic climate change presents an urgent threat to ecosystems, public health and economic stability. Even single degree increases in global temperatures can trigger irreversible impacts, ranging from biodiversity loss and food insecurity...
Published: 3/3/2026   |   Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Environment, Featured, Materials & Chemicals, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
Integrating AI in Back Injury Prevention
This wearable technology integrates sensors into a back brace and shoe inserts to monitor posture and movement. Using AI-driven analysis, it provides real-time feedback via a software application, helping Direct Care Workers prevent the risk of back injuries during lifting and transfer tasks. Background: Workplace injuries, particularly musculoskeletal...
Published: 2/25/2026   |   Inventor(s): Yuchi Young
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Artificial Intelligence, Technology Classifications > Healthcare
A novel synthetic constitutive-active glucocorticoid receptor
Introducing "superGR," a novel synthetic glucocorticoid receptor fusion protein designed to enhance glucocorticoid therapy by providing ligand-independent activation and improved gene regulation for inflammatory diseases. Background: Glucocorticoids are widely used to treat inflammatory conditions like severe alcoholic hepatitis and sepsis,...
Published: 2/19/2026   |   Inventor(s): Hong Lu, Conor Fahy
Keywords(s): gene therapy, glucocorticoid, inflammatory liver disease, lung injury, sepsis, synthetic materials, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Luminescent biosensor for detection of nucleotide sequences, small molecules, and proteins at the point-of-care
This technology is a modular, luminescent biosensor that rapidly detects DNA, RNA, small molecules, and proteins at the point of care, using a visible color change measurable by a smartphone, enabling fast, sensitive, and equipment-free diagnostics. Background: Molecular diagnostics is a rapidly evolving field that plays a critical role in the detection...
Published: 2/19/2026   |   Inventor(s): Harsimranjit Sekhon, Stewart Loh
Keywords(s): bio/chemical sensors, bioluminescence, biomarker diagnostics, biosensor, nanoluciferase, Technologies, therapeutic drug monitoring, Virus Detection
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
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