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ATR_FTIR spectroscopy of saliva and machine learning as a screening test for the Sjögren disease

This technology uses saliva analysis with infrared spectroscopy and machine learning to provide a fast, non-invasive, and accurate test for Sjögren’s Disease, filtering out unreliable data to improve diagnosis and potentially screen for other diseases. Background: Sjögren’s disease is a chronic autoimmune disorder that primarily...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Igor Lednev, Bhavikkumar Vyas, Jürgen Popp, Oleg Ryabchykov

Keywords(s): diagnostics, Salivary biomarkers, Sjogren Disease, spectroscopy, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Diagnostics

Temporal Control of CRISPR-Cas9 using Bio-orthogonal Chemistry.

This technology enables precise, time-controlled activation or deactivation of CRISPR-Cas9 genome editing using biocompatible chemical reactions, reducing off-target effects and improving the safety and accuracy of gene editing for research and therapeutic applications. Background: Genome editing technologies, particularly CRISPR-Cas9, have revolutionized...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Maksim Royzen, Bhoomika Pandit

Keywords(s): biochemistry, CRISPR, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Gene Therapy

Bruton's Tyrosine Kinase as Anti-Cancer Drug Target

This technology identifies Bruton's Tyrosine Kinase (BTK) as a novel target in breast cancer therapy and provides methods for treatment and diagnosis by inhibiting a specific BTK variant. Background: Protein tyrosine kinases (PTKs) are essential enzymes involved in cellular communication and regulation, often playing a significant role in cancer...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Douglas Conklin, Antonis Kourtidis, Cheryl Eifert

Keywords(s): breast cancer, cancer, TAF, Technologies, therapeutic targets

Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany

Spectroscopic Method for Diagnostics of Alzheimer's Disease

This technology provides a non-invasive, spectroscopic method using Raman spectroscopy to diagnose and monitor Alzheimer’s disease by analyzing biochemical changes in blood serum. Background: Alzheimer’s disease presents significant diagnostic challenges, often requiring invasive or costly procedures with limited early detection capabilities....

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Igor Lednev

Keywords(s): Alzheimer's, blood, diagnostics, neurodegeneration, Raman spectroscopy, statistical analysis, TAF, Technologies, vibrational spectroscopy

Category(s): Technology Classifications > Diagnostics, Campus > University at Albany

Diagnosing Alzheimer's via Raman Spectroscopic Analysis of Saliva

This technology provides a non-invasive method for early detection of cognitive diseases using spectroscopic analysis of saliva samples combined with advanced statistical and neural network models. Background: Cognitive diseases such as Alzheimer's and mild cognitive impairment (MCI) represent significant challenges in healthcare due to their...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Igor Lednev, Nicole Ralbovsky, Cay Anderson-Hanley

Keywords(s): Alzheimer's, diagnostics, saliva, solar cells, TAF, Technologies

Category(s): Technology Classifications > Diagnostics, Campus > University at Albany

Structurally and Functionally Diverse Heterocyclic Dipeptide Isosteres and Their Derivatives as Antimicrobial Agents and Peptidomimetic Building Blocks

This technology enables rapid, modular synthesis of diverse heterocyclic dipeptide isosteres with potent antimicrobial activity, which can be easily incorporated into peptides to create stable, bioactive molecules for drug discovery and therapeutic applications. Background: The field of antimicrobial drug discovery and peptidomimetic development...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Sujit Suwal, Olga Novikova

Keywords(s): antibacterial, Bioactive heterocyclic amino esters and peptidomimetics, Chemo-selective synthesis of heterocyclic amino esters, iterative Buchwald Hartwig amination and Suzuki coupling, Technologies

Category(s): Campus > Buffalo State College, Technology Classifications > Drug Design and Synthesis

A layer-by-layer mass spectrometry intensity method for de novo direct sequencing of RNA therapeutics and impurities

3D NGMS-Seq is a mass spectrometry-based technology that accurately sequences all RNA types and impurities in mixed samples, enabling comprehensive analysis of RNA therapeutics for drug development, quality control, and regulatory compliance. Background: The field of RNA-based therapeutics has experienced rapid growth due to the success of mRNA vaccines...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Shenglong Zhang

Keywords(s): Mass spectrometry imaging, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Bioinformatics, Technology Classifications > Therapeutics and Vaccines

Optomechanical Acoustic Particle Velocity Sensor

Inspired by biological hearing systems, this invention provides an ultrasensitive, low-noise, miniaturized optomechanical acoustic particle velocity sensor that detects weak velocity signals in confined spaces. By directly sensing acoustic particle velocity rather than pressure, it measures vector components of sound fields, enabling enhanced localization...

Published: 4/30/2026 | Updated: 4/30/2026 | Inventor(s): Jian Zhou., Ronald Miles, Wanyin Zheng, Wei Sun, Xiangyu Wei

Keywords(s): Technologies

Category(s): Campus > Binghamton University, Technology Classifications > Electronics, Technology Classifications > Engineering

Electromotive anti fibrotic substance administration for fibrotic diseases

This technology uses a gentle electrical current to deliver antifibrotic drugs like collagenase directly into fibrotic tissues, such as the bladder wall, enabling noninvasive, targeted treatment of fibrosis and improving tissue function without surgery. Background: Fibrosis of the bladder wall, particularly in the context of neurogenic bladder, represents...

Published: 4/28/2026 | Updated: 4/28/2026 | Inventor(s): Jeffrey Villanueva

Keywords(s): fibrosis, fibrous materials, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering

Fluorescent Peptides for Membrane Tension Reporting and Biomarkers

A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension. Background: The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...

Published: 4/23/2026 | Updated: 4/15/2026 | Inventor(s): Thomas Suchyna, Sergei Sukharev

Keywords(s): Featured, Research Tool, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials

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