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Search Results - technologies
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Developing a new mechanism-based method to treat behavioral variant frontotemporal dementia
This technology offers a novel, mechanism-based therapeutic method using oxytocin and specific compounds to treat social-affective deficits in behavioral variant frontotemporal dementia (bvFTD). Background: Behavioral variant frontotemporal dementia (bvFTD) is a prevalent form of dementia characterized by severe social and emotional impairments,...
Published: 3/30/2026
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Updated: 3/30/2026
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Inventor(s):
Wei-Dong Yao
Keywords(s):
dementia
,
electrophysiology
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Healthcare
,
Technology Classifications > Therapeutics and Vaccines
Computer vision-based human movement analysis for physical therapists and trainers
This technology is a computer vision-based software platform that enables real-time human movement analysis, providing physical therapists and trainers with objective feedback and progress tracking through a standard webcam. Background: Traditional physical therapy and fitness training often rely on subjective visual assessments, which can limit...
Published: 3/30/2026
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Updated: 3/25/2026
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Inventor(s):
Bokkyu Kim
Keywords(s):
medical devices
,
medical imaging
,
Technologies
Category(s):
Technology Classifications > Computer Software
,
Campus > Upstate Medical University
β-Catenin agonists recapitulate the protective effects of genetic stabilization
This technology uses drugs that stabilize β-catenin to boost protective immune cells in the lungs, reducing damage from pulmonary hemorrhage and inflammatory lung diseases by activating a novel immunomodulatory pathway. Background: Pulmonary hemorrhage and other inflammatory lung diseases represent significant clinical challenges due to their...
Published: 3/30/2026
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Updated: 3/24/2026
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Inventor(s):
Mobin Karimi
Keywords(s):
gene coding
,
gene therapies
,
gene therapy
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Biomedical Science and Engineering
Harnessing IL15C and NKG2D for Potent and Persistent CAR T Cell Therapy in TNBC
This technology is an advanced CAR T-cell therapy for triple-negative breast cancer that uses engineered T-cells to recognize and kill cancer cells regardless of HLA status and includes a built-in IL-15 signal to boost T-cell survival and effectiveness. Background: Triple-Negative Breast Cancer (TNBC) is a particularly aggressive subtype of breast...
Published: 3/30/2026
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Updated: 3/24/2026
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Inventor(s):
Mobin Karimi
Keywords(s):
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Biomedical Science and Engineering
Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties BACKGROUND: The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 3/31/2026
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Updated: 3/23/2026
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Inventor(s):
Chong Cheng
,
Mingxuan Zhang
,
Yun Wu
,
Ziwen Zhang
Keywords(s):
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Biological Materials
,
Technology Classifications > Diagnostics
,
Technology Classifications > Drug Delivery
,
Technology Classifications > Materials and Chemicals
,
Technology Classifications > Research Tools and Reagents
Apelin-Receptor (APJ) Antagonists
A series of stable, small molecule compounds that inhibit an alternative (non-VEGF) angiogenic pathway that is overexpressed in a variety of cancers. Background: Antiangiogenic drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway are widely used to treat solid tumors and ocular conditions such as wet AMD. However, anti-VEGF...
Published: 3/31/2026
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Updated: 3/23/2026
|
Inventor(s):
Youngjae You
,
Sukyung Woo
,
Ganesh Bist
,
Ahmed Elsheikh
Keywords(s):
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Drug Design and Synthesis
Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers BACKGROUND: There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials. TECHNOLOGY...
Published: 3/31/2026
|
Updated: 3/23/2026
|
Inventor(s):
Chong Cheng
,
Mingxuan Zhang
,
Yun Wu
,
Ziwen Zhang
Keywords(s):
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Drug Delivery
,
Technology Classifications > Materials and Chemicals
,
Technology Classifications > Research Tools and Reagents
,
Technology Classifications > Biological Materials
,
Technology Classifications > Diagnostics
Novel Fusion Protein Vaccine for Moraxella Catarrhalis Infections
A fusion protein vaccine designed to prevent COPD exacerbations and pediatric acute otitis media. Background: Respiratory infections caused by Moraxella catarrhalis (Mcat) represent a growing public health concern. In children, Mcat is a leading cause of otitis media, a common middle ear infection affecting most children by age three, frequently...
Published: 3/30/2026
|
Updated: 3/23/2026
|
Inventor(s):
Timothy Murphy
,
Patricia Weber
Keywords(s):
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Antibodies
Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026
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Updated: 3/19/2026
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Inventor(s):
Yamin Li
,
Yuqin Men
,
Qinghe Meng
,
Robert Cooney
Keywords(s):
anti-inflammatory therapeutic
,
drug delivery
,
lipids
,
mRNA
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Healthcare
Swirl Burner with Satellite Combustion Ignitor
This advanced swirl combustion burner uses special mixing vanes, a secondary ignitor, and an oxidation catalyst to ensure stable, efficient burning of any gaseous fuel while reducing carbon monoxide emissions by up to 99%, making it cleaner and more adaptable for industry. Background: Industrial combustion systems are foundational to a wide range...
Published: 3/19/2026
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Updated: 3/19/2026
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Inventor(s):
David Waage
Keywords(s):
Technologies
Category(s):
Campus > SUNY Cobleskill
,
Technology Classifications > Clean Energy
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