Search Results - anti-infectives

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Antibacterial Peptides, Synbodies, and Methods of Discovery
Antibiotic resistance is a worldwide clinical and public health problem, primarily stemming from the overuse of antibiotics. One of the most critical resistant pathogens is Methicillin-resistant Staphylococcus aureus (MRSA), which accounts for over 2,000,000 illnesses and 11,000 deaths each year. MRSA has developed resistance to all beta-lactam antibiotics....
Published: 2/23/2023   |   Inventor(s): Chris Diehnelt, Stephen Johnston
Keywords(s): Antibiotic Resistance Treatments, Antibiotics, Anti-Infectives, Infectious Disease, Therapeutics
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Vaccines/Antimicrobials, Pharmaceuticals, Proteomic Assays/Reagents/Tools
Antibacterial Peptides, Synbodies, and Methods of Discovery
Antibiotic resistance is a worldwide clinical and public health problem, primarily stemming from the overuse of antibiotics. One of the most critical resistant pathogens is Methicillin-resistant Staphylococcus aureus (MRSA), which accounts for over 2,000,000 illnesses and 11,000 deaths each year. MRSA has developed resistance to all beta-lactam antibiotics....
Published: 2/23/2023   |   Inventor(s): Chris Diehnelt, Stephen Johnston, Pamela Hall
Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, Antibiotics, Anti-Infectives, Drug Discovery, Infectious Disease, Peptides, Therapeutics
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools, Pharmaceuticals, Vaccines/Antimicrobials
Antibiotic Susceptibility Testing
Antibiotic-resistant bacterial infections cost billions of dollars to the US in healthcare and result in 2 million hospitalizations and 23,000 deaths. Clinical treatment of bacterial infections, especially in acute cases of sepsis, requires multiple steps, including antibiotic susceptibility tests (AST). Current AST techniques are slow and limited to...
Published: 2/23/2023   |   Inventor(s): Nongjian (nj) Tao, Karan Syal
Keywords(s): Antibiotic Resistant Bacteria, Antibiotics, Antibodies, Antibody Therapeutics, Anti-Infectives
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Imaging, Life Science (All LS Techs), Medical Diagnostics/Sensors
Scalable, Highly Immunogenic, Polysaccharide-Peptide Nanoparticle Vaccine for Protection against Many Bacterial Serotypes
Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...
Published: 7/18/2024   |   Inventor(s): Nikolas Weissmueller, Robert Prud'homme, Ruth Rosenthal
Keywords(s): anti-infectives, drug delivery, nanotechnology, vaccines
Category(s): Biotechnology/Pharmaceuticals
Behaviorally-motivated Innovation for Hand Hygiene and Infection Control
Princeton Docket # 15-3154-1Researchers at Princeton University, departments of psychology and public affairs, along with researchers at Sunnybrook Health Sciences Centre, Toronto, have co-developed a behaviorally motivated innovation for infection control and hand hygiene.Clinician failure to wash hands before interacting with patients is a well-recognized...
Published: 2/14/2024   |   Inventor(s): Eldar Shafir, Donald Redelmeir
Keywords(s): anti-infectives
Category(s): Chemistry, Medical Devices/Diagnostics
ClpP is a Major Regulator in NO Stressed E Coli
Discovery of ClpP Protein, a Major Regulator in Nitric Oxide Stressed Escherichia coli, for Anti-infective Development Strategies Princeton Docket # 15-3064 Antibiotic resistance has become a public health crisis, while the rate of new antibiotic development declines. A promising solution is antivirulence therapy, which targets host-pathogen interactions,...
Published: 2/14/2024   |   Inventor(s): Mark Brynildsen, Jonathan Robinson
Keywords(s): antibiotics, anti-infectives, biomarker/diagnostic, life science research tools, metabolic engineering, protein engineering
Category(s): Biotechnology/Pharmaceuticals, Chemistry
Novel Cell Line for Hepatitis B Drug Discovery and Research
Novel Cell Line for Hepatitis B Drug Discovery and Research Princeton Docket # 15-3077 Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...
Published: 2/14/2024   |   Inventor(s): Alexander Ploss, Benjamin Winer
Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology
Category(s): Biotechnology/Pharmaceuticals
Clinical Trial Capability
Researchers who perform both clinical work and research in their specific fields of expertise are highly sort after by industry to study the latest therapies. They provide customers with credible, reliable and unbiased results which are highly regarded by regulators.The University of Adelaide's areas of expertise include:- Pain and Anaesthesia- Cardiology-...
Published: 9/7/2017   |   Inventor(s):  
Keywords(s): Addiction / Drug Dependency, Analytical Services, Anti-infectives, Assays, AutoImmune, Biology, Biomaterials, Biopharmaceuticals, Biosensing, Cancer, Cardiovascular Disease, CNS, Contraception, Diabetes, Drug Delivery, Drug Development, Endocrinology, Gastroenterology, Gastrointestinal, Gene/Cell Therapy, Genetic Disorders, Haematology, Hormone Therapy, Immunology, Infectious Disease, Inflammation, Medical Device, Mental Health, Metabolic Disease, Musculoskelatal, Neurology, Oncology, Ophthalmic, Osteo / Bone, Pathology, Pharmacogenetics, Pulmonary, Regenerative Medicine, Renal, Reproductive, Respiritory, Skin/Dermatological, Systems Biology, Urological, Vaccines
Category(s): Medical, Biomedical, Biotechnology, Dental, Devices, Diagnostic, Drug Delivery, Drug Discovery, Drug Screening, Gene Therapy, Genomics/Genetics, Nanotechnology, Therapeutic
Three Dimensional Multi-resolution Microscope (3DMM) for High-definition Imaging of Cell-biological Events
Docket # 13-2834-1The market for biological microscopes is greater than $1 billion annually. There is a high demand in the biomedical research field for microscopes which are capable of resolving ever smaller features and faster dynamics in live cells. However, currently available biological microscopes are limited in their ability to follow phenomena...
Published: 12/12/2022   |   Inventor(s): Haw Yang, Kevin Welsher
Keywords(s): anti-infectives, anti-viral, Biotechnology/Pharmaceuticals, cancer/oncology, Imaging, life science research tools, microscopy, research tool
Category(s): Medical Devices/Diagnostics, Chemistry, Biotechnology/Pharmaceuticals
Microfluidic Device for the Study and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices
Methods and Microfluidic Device for the Study, Testing and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices Docket # 13-2880Researchers at Princeton University have developed a microfluidic system and method to investigate biofilm morphologies under more realistic physical conditions which could be used to screen potential...
Published: 9/8/2022   |   Inventor(s): Bonnie Bassler, Howard Stone, Martin Semmelhack, Knut Drescher, Yi Shen, Colleen O'loughlin, Laura Miller Conrad
Keywords(s): antibiotics, anti-infectives, Biotechnology/Pharmaceuticals, life science research tools, medical device
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics