Search Results - antibodies

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Anticancer Agent with N-Glycan Specificity
Application An engineered protein for targeting disease-associated N-glycans. Key Benefits High affinity, pH insensitive, no cofactors required. Applications in anticancer and antiviral therapeutics and research. Can aid in manufacturing monoclonal antibodies with desired N-glycosylation properties. Market Summary Glycosylation involves post-translation...
Published: 11/3/2025   |   Inventor(s): Eric J. Sundberg, Diego Sastre, Maros Huliciak
Keywords(s): Antibodies, Biologics, Biomarkers, Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Microbiology and Infectious Disease Treatments, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Combinatorial Therapy for Preserving Muscle Mass During Weight Loss
Application A combinatorial therapy to preserve muscle mass during semaglutide weight loss treatment. Key Benefits Preserves lean mass during semaglutide treatment in preclinical mouse models. Increases overall fat loss without affecting food/water intake during semaglutide treatment in preclinical mouse models. Market Summary The prevalence...
Published: 11/5/2025   |   Inventor(s): Todd Golde, Yong Ran, Eric Krause, Annette De Kloet, Karen Scott
Keywords(s): Antibodies, Biologics, Drug Discovery, Drug Target Identification, Metabolic Disease Treatments, Musculoskeletal Treatments, Personalized Medicine
Category(s): TechPub Algolia > Therapeutics
Sweat as a Biofluid for Analysis and Disease Identification
Noninvasive sampling is critical for certain patient populations, such as hemophiliacs, neonates, elderly or immunocompromised individuals, especially if they require daily monitoring. Blood sampling is painful, inconvenient and often difficult and increases the risk of exposure to infectious agents, which can be devastating to immunocompromised populations....
Published: 8/27/2025   |   Inventor(s): Benjamin Katchman, Karen Anderson, Jennifer Blain Christen
Keywords(s): Antibiotic Resistant Bacteria, Antibodies, Autoantibody, biomarker, Defense/military, Diagnostics, Sweat
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity
An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva. Background: Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 5/13/2025   |   Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
A Rapid, High Content, Reagent Sparing, Fluorescent Plasmonic Assay Platform for Multiplexed Serum Antibody Detection in Lyme Disease and COVID-19
A protein microarray, in the form of a compact biochip, that can be analyzed with high sensitivity using GC-FP technology. Background: Some infectious diseases are easy to diagnose, but others are much more difficult. One example is Lyme disease (B. burgdorferi), which is caused by a slow-growing organism that takes many weeks to detect. Current...
Published: 8/13/2025   |   Inventor(s): Nathaniel Cady
Keywords(s): antibodies, assays, COVID-19, nanobioscience, nanobiotechnology, screens and assays, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Screens and Assays, Campus > SUNY Polytechnic Institute
Antibody Against Inositol 1,4,5-Trisphosphate Receptor Type 2 (anti-IP3R antibody)
Antibody against the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) type 2 Background: The inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is an intracellular Ca²⁺-release channel located on the endoplasmic reticulum (ER). IP3R2 is characterized by a high sensitivity to both IP3 and ATP and is biphasically regulated by Ca²⁺. Furthermore,...
Published: 5/13/2025   |   Inventor(s): Richard Wojcikiewicz
Keywords(s): antibodies, antibody
Category(s): Technology Classifications > Antibodies, Campus > Upstate Medical University
Anti-Green Fluorescent Protein Antibodies
Applications Western Blot Immunocytochemistry Immunohistochemistry Specificity Vertebrates Subtype Chicken Polyclonal Immunogen His-tagged green fluorescent protein of the bioluminescent hydrozoan jellyfish (Aequorea Victoria). Technical Summary Drs. Tomasiewicz, Wood, & Flaherty have created a polyclonal anti- green fluorescent...
Published: 2/13/2025   |   Inventor(s): Henry Tomasiewicz, John Wood, Denise Flaherty
Keywords(s): Antibodies
Category(s): TechPub Algolia > Research Tools
Sarcospan Antibodies for Biomedical Application (UCLA Case No. 2024-082)
UCLA researchers in the Department of Integrative Biology and Physiology have developed a set of novel and highly specific sarcospan antibodies for use in basic and translational research. BACKGROUND: Sarcospan (SSPN) is a broadly expressed cell surface 25 kDa transmembrane protein. SSPN is critical for the function of adhesion complexes in skeletal...
Published: 7/17/2025   |   Inventor(s): Rachelle Crosbie, Ekaterina Mokhonova
Keywords(s): Antibodies, Becker muscular dystrophy, Duchenne muscular dystrophy, ELISA, immunoblotting, immunofluorescence, immunoprecipitation, musculoskeletal disorders, sarcospan
Category(s): Life Science Research Tools > Antibodies, Therapeutics > Musculoskeletal Disease
EF-Tu Targeting Antibody for Infection Treatment
Application Therapeutic monoclonal antibodies directed to Elongation Factor-Tu (EF-Tu) for the treatment of infections. Key Benefits An antibody that targets the protein EF-Tu, which is present on many types of bacteria involved in life-threatening infections. A research-grade antibody has been developed with animal data showing the ability to...
Published: 9/22/2025   |   Inventor(s): Joanna Goldberg, Dina Moustafa
Keywords(s): Antibodies, Microbiology and Infectious Disease Treatments, Therapeutic Vaccines
Category(s): TechPub Algolia > Vaccines, TechPub Algolia > Therapeutics
Human and Improved Murine Monoclonal Antibodies Against CD22
Abstract: CD22 is a common cell surface glycoprotein expressed in B-cells and present in B-cell lymphomas; e.g., hairy cell leukemia (HCL), non-Hodgkins lymphoma (NHL), chronic lymphoblastic leukemia (CLL), and other cancers. It is therefore a target for cancer immunotherapy. Conjugation of anti-CD22 monoclonal antibodies with toxins or drugs has shown...
Published: 4/22/2025   |   Inventor(s): Dimiter Dimitrov, Xiaodong Xiao, Ira Pastan
Keywords(s): antibodies, ANTIGEN, B-CELL, B-Cell Lymphoma, Bcl, CANCER, CD22, Chronic Lymphoblastic Leukemia, CLL, Dimitrov, Hairy cell leukemia, HCL, Human, monoclonal, NHL, non-Hodgkins lymphoma, Oncology
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
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