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Search Results - infectious+disease
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Antibodies for treatment of coronavirus disease
NU 2023-247 INVENTORS Huiping Liu* Deyu Fang* Hannah Mubarak Andrew Hoffmann Nurmaa Dashzeveg Lamiaa El-Shennawy Juncheng Wei Wuwei Tan Yang Shen SHORT DESCRIPTION Computationally redesigned antibodies targeting SARS-CoV-2 for treating COVID-19. BACKGROUND The continuous evolution of SARS-CoV-2 has allowed the virus to escape most therapeutic...
Published: 2/26/2026
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Inventor(s):
Keywords(s):
Antibody
,
Artificial Intelligence & Machine Learning
,
Biologic
,
Infectious disease
,
Research tool
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
System for Reversible Control of Morphotype Switching in Mycobacterium abscessus for Enhanced Disease Modeling and Therapeutic Research
Invention Description Antibiotic-resistant nontuberculous mycobacteria (NTM) infections are increasing at ~8% annually, placing a significant burden on healthcare systems. Mycobacterium abscessus (Mabs) represents one of the most treatment-refractory pathogens, particularly in cystic fibrosis (CF) patients. Mabs disease severity is strongly associated...
Published: 2/26/2026
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Inventor(s):
Shelley Haydel
,
Rodrigo Aguilera Olvera
,
Lexi Yakimovich
Keywords(s):
Antibiotic Resistance Treatments
,
Antibiotic Resistant Bacteria
,
CRISPR-Cas
,
Gene Expression
,
Infectious Disease
,
Microbes, bacteria, fungi, virus, yeast
,
Microbiology
,
Mycobacteria
,
mycobacterial genetics
,
Pathogen
Category(s):
Life Science (All LS Techs)
,
Non-Cancer Therapeutics
,
Nucleic Acid/Peptide/Protein Therapies
ACE2+ Exosomes for COVID-19 Decoy Therapy
PROPOSED TITLE: ACE2+ Exosomes for COVID-19 Decoy Therapy NU NUMBER NU 2020-145 INVENTORS Deyu Fang* Huiping Liu* Andrew Hoffmann Emma June Schuster Lamiaa El-Shennawy Nurmaa Dashzeveg SHORT DESCRIPTION This invention provides exosomes loaded with ACE2 protein or viral antigen-specific IgGs for treatment of COVID-19. BACKGROUND The COVID-19...
Published: 11/17/2025
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Inventor(s):
Keywords(s):
COVID-19
,
Drug delivery
,
Infectious disease
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Methods for assembling peptides into peptide amphiphile nanofibers
TITLE: Peptide Nanofiber Assembly for Enhanced Therapeutic Delivery NU 2020-081 SHORT DESCRIPTION This technology uses self-assembling peptide amphiphile nanofibers to protect and deliver therapeutic peptides. It reduces degradation and improves delivery efficiency for advanced treatment applications. BACKGROUND Peptide therapeutics offer promise...
Published: 1/9/2026
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Inventor(s):
Keywords(s):
Brain injury
,
Drug delivery
,
Infectious disease
,
Nanomaterials
,
Neurodegenerative disease
,
Neurologic disease
,
Neurology
,
Neurovascular
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Human antibodies targeting a novel flu epitope for use as a universal flu vaccine and treatment
Technology Summary: Scientists at Vanderbilt have discovered a new class of human antibodies specific to a novel target for the detection, prevention, and treatment of influenza A viruses (IAV). Using structural characterization, they have identified a novel antigenic site on the hemagglutin (HA) head domain that may be targeted by multiple antibodies...
Published: 8/28/2025
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Inventor(s):
Keywords(s):
Infectious Disease
Category(s):
Therapeutics
,
Vaccines
Self-powered, bioresorbable drug release systems
NU 2023-045 INVENTORS John Rogers* Colin Franz* Yamin Zhang SHORT DESCRIPTION Northwestern and Shirley Ryan AbilityLab researchers have developed a novel, self-powered, bioresorbable drug delivery system that enables light-controlled, targeted drug release without the need for surgical removal post-treatment. BACKGROUND Current drug delivery systems...
Published: 11/6/2025
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Inventor(s):
Keywords(s):
Biomaterials
,
Cancer/Oncology
,
Drug delivery
,
Infectious disease
,
Medical device
,
Therapeutics
Category(s):
Life Sciences > Healthcare Devices, Tools & IT
An iron oxide nanozyme formulation for augmenting the efficacy of oral care products.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay. Problem: Tooth decay (dental caries), caused by the destruction of the outer layer (enamel) of teeth by bacteria in biofilms, affects nearly half of the global population and remains the most prevalent chronic disease...
Published: 8/19/2025
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Inventor(s):
Yue Huang
,
Hyun (Michel) Koo
,
David Cormode
Keywords(s):
Bioengineering
,
Dentistry
,
Infectious Disease
,
Microbiome
,
Nanotechnology
,
Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Materials
,
Technology Classifications > Therapeutics
Methods and Sequences for mRNA and Other HIV Vaccine Development
Unique sequences eliciting broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) that could be used to develop effective mRNA-based and other types of HIV vaccine. Problem: Despite decades of research, there is currently no vaccine to prevent HIV infection. A major goal of HIV vaccine programs is to generate bNAbs, which...
Published: 8/1/2025
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Inventor(s):
George Shaw
,
Edward (Ted) Kreider
,
Beatrice Hahn
,
Ashwin Skelly
,
Hui Li
,
Drew Weissman
Keywords(s):
Bioengineering
,
HIV/AIDS
,
Immunology
,
Infectious Disease
,
Protein/Peptide (Non-Antibody)
Category(s):
Technology Classifications > Vaccines
Intranasally-Delivered Therapy For The Treatment Of Depression And Dementia
Intranasal nasal dantrolene nanoparticles alone, or in combination with lithium, can provide protection against depression and dementia with minimal or no side effects. Problem: Major depression disorder (MDD) affects 350 million patients in the world and about 16% of the population in USA. In addition, up to 50% of Alzheimer’s disease (AD)...
Published: 8/1/2025
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Inventor(s):
Huafeng Wei
Keywords(s):
Aging
,
Immunology
,
Immunoncology
,
Infectious Disease
,
Inflammation
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Therapeutics
Compositions and Methods for the Treatment of Intestinal Inflammation
NU 2021-252 INVENTORS Matthew Bury Muthukumar Gunasekaran Sunjay Kaushal Arun Sharma* Tiffany Sharma BACKGROUND Crohn’s Disease (CD) is partly caused by a highly pro-inflammatory lesion microenvironment which subsequently causes numerous clinical complications. Northwestern University scientists have developed a method to control...
Published: 2/6/2026
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Inventor(s):
Keywords(s):
AUTM26C1
,
BIAUTM1
,
Cell therapy
,
IBD - Inflammatory bowel disease
,
Immunotherapy
,
Infectious disease
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
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