Search Results - oncology

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Novel AKR1C3 Inhibitors in Cancer
Inhibitors and tools to block the local formation of steroid hormones in hormone-dependent malignancies of the prostate, breast and endometrium Value Proposition: Standard treatment of care for hormone-dependent tumors utilizes hormone ablative therapies. These agents non-discriminately block the action of estrogens and androgens and have untoward side...
Published: 9/25/2025   |   Inventor(s): Trevor Penning, Adegoke Adeniji, Michael Byrns, Jeffrey Winkler, Barry Twenter, Lawrence Marnett, Andy Liedtke
Keywords(s): Men's Health, Oncology, Small Molecule, Women's Health
Category(s): Technology Classifications > Therapeutics
Decision Support Tool for Detection of Prostate Lesions on MRI
Prostate cancer diagnostic software that provides expert-level lesion detection, localization, automated segmentation, and automated report generation in less than 45 seconds. Background: According to the American Cancer Society, about 1 in 8 men will be diagnosed with prostate cancer during their lifetime. American Urologic Association guidelines...
Published: 9/25/2025   |   Inventor(s): Thomas Sanford, Gennady Bratslavsky
Keywords(s): magnetic resonance imaging, oncology, prostate, software, Technologies
Category(s): Technology Classifications > Healthcare IT, Campus > Upstate Medical University
Treatment of viral induced cancers
Docket# S4039 Technology: Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus(KSHV) are human γ-herpesviruses associated with a broad spectrum of B-cell lymphomas typically in immune-compromised populations. There are no drugs which can specifically target EBV/KSHV-associated B-cell tumors. Using a High-throughput Screen...
Published: 8/7/2025   |   Inventor(s): Erle Robertson
Keywords(s): Oncology
Category(s): Technology Classifications > Therapeutics
Peptides For Solid Cancer Tumor Immunotherapy Treatment
Short, multivalent peptide antagonists to block macrophage immune-receptor SIRPα, promoting cancer cell phagocytosis. Problem: Modern cancer cell immunotherapies incorporate immune checkpoint blockade mechanisms, where prominent therapies target functionally suppressed immune cells in tumor microenvironments. Relieving this suppression allows...
Published: 9/17/2025   |   Inventor(s): Dennis Discher, AbdelAziz Jalil
Keywords(s): Cell Therapy, Immunology, Oncology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics, Technology Classifications > Vaccines
Stratification Method that Determines the Prognosis of Breast Cancer at a Personalized Level
A reliable, accurate, and versatile method for determining the prognosis of primary breast cancer tumors post-surgery. Background: Breast cancer is the second most common type of cancer in women in the United States, after skin cancer. On rare occasions, it can also occur in men. According to the American Cancer Society, nearly 300,000 new cases...
Published: 5/13/2025   |   Inventor(s): Vladimir Kuznetsov, Leszek Kotula
Keywords(s): biomarkers, biostatistics, breast cancer, diagnostics, functional genomics, gene expression analysis, oncology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
Synthesis of Anticancer Agents Nannocystins and Their Analogs
Synthetic route to producing nannocystins, an anticancer agent that is typically found in myxobacteria. Background: Myxobacteria are some of the top producers of microbial secondary metabolites, a large portion of which have shown activity against human diseases. One of these metabolite groups are nannocystins, since they have shown excellent anticancer...
Published: 5/13/2025   |   Inventor(s): Zhang Wang, Jun Huang
Keywords(s): drug delivery, oncology
Category(s): Technology Classifications > Research Tools and Reagents, Campus > University at Albany
Profiling Chemically Modified DNA/RNA Units for Disease and Cancer Diagnosis
Diagnose a wide variety of conditions by analyzing DNA and RNA nucleotides/nucleosides. Background: In theory, RNA and DNA can be used to diagnose a broad range of diseases. Unfortunately, there are no existing technologies capable of providing comprehensive profiles of variant DNA/RNA components. Established approaches for the analysis/detection of...
Published: 5/13/2025   |   Inventor(s): Daniele Fabris, Rebecca Rose
Keywords(s): cancer, DNA modifications, epigenetics, genome-wide analysis, infection, oncology, RNA modifications, Technologies
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
Reducing The Adverse Side Effects Of Using Native T-Cells To Destroy Cancer Cells
A Switchable Bispecific T-Cell Nanoengager (sBiTNE) to link T cells with cancer cells that can be reversed if off-tumor toxicity is detected. Problem: Compounds which link native T-cells with the surface antigens found on cancer cells have emerged as an effective treatment for blood malignancies and are currently being developed for solid tumors....
Published: 10/10/2025   |   Inventor(s): Michael Mitchell, Ningqiang Gong
Keywords(s): Bioengineering, Immunology, Immunoncology, Immunotherapy, Oncology, Platform Technology, Protein/Peptide (Non-Antibody), Small Molecule
Category(s): Technology Classifications > Therapeutics
Targeted, Enhanced Modification Of Lipid NanoparticlesTto Improve Tumor Therapeutic Efficacy
A method to inhibit small extracellular vesicles (sEVs) released by tumor cells to enhance lipid nanoparticle (LNP) accumulation in tumors. Problem: Lipid nanoparticles (LNPs) have shown promise as drug delivery systems for various diseases with several clinically approved products. However, their ability to deliver genes specifically to tumor cells...
Published: 10/3/2025   |   Inventor(s): Michael Mitchell, Ningqiang Gong, Wenqun Zhong, Wei Guo
Keywords(s): Bioengineering, Drug Delivery, Immunoncology, Oncology
Category(s): Technology Classifications > Therapeutics
Brain Cancer: Novel Prognostic Method and Therapeutic Target for Glioblastoma
Advantages: A precision-guided method for identifying glioblastoma-related genes that improves assessment of the current prognostic biomarker Enables the identification of potential novel therapeutic targets: GLP1R agonists, which are already used for managing obesity and type 2 diabetes, could be explored as treatments for GBM Broader Applications:...
Published: 9/3/2025   |   Inventor(s): George Blanck, Teresa Thomas
Keywords(s): Cancer Diagnostics, Medical Diagnostics, Oncology, Therapeutics
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Oncology, Technology Classifications > Medical > Therapeutics
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