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Search Results - oncology
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Benzofuranoindoline-Containing Fungal RiPP-Derived Anticancer Compounds
Benzofuranoindoline-containing fungal RiPP-derived compounds and analogs, plus pharmaceutical compositions, and administration methods for treating cancers, including leukemia. Problem: The disclosure targets diseases and disorders where new therapeutic compounds are needed, including cancers such as leukemia. Fungal ribosomally synthesized and post-translationally...
Published: 4/16/2026
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Updated: 4/16/2026
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Inventor(s):
Xue Sherry Gao
,
Hans Renata
,
Qiuyue Nie
Keywords(s):
Oncology
,
Small Molecule
Category(s):
Technology Classifications > Therapeutics
A Fast and Accurate Computational Method for Radiation Treatment Planning
A computational method for calculating the dose, Linear Energy Transfer and Relative Biological Effectiveness of proton treatment planning and optimization. Problem: In radiation therapy, the dose absorbed by cells determines their probability of survival. However, the biological effectiveness of the dose can vary. Multiple factors influence this variability,...
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Alejandro Carabe Fernandez
,
Alejandro Bertolet Reina
,
Miguel Cortes Giraldo
Keywords(s):
Oncology
,
Platform Technology
,
Radiology
Category(s):
Technology Classifications > Testing & Measurement
,
Technology Classifications > Imaging
,
Technology Classifications > Medical Devices
A Precise and Effective Method of Proton Beam Therapy for Cancer Treatment
A method of proton beam therapy using a single energy proton beam delivered at multiple angles to the tumor. Problem: Proton therapy is a type of radiation treatment that uses high-energy protons to damage and kill cancer cells. To maximize therapeutic efficacy while limiting collateral damage to healthy cells, proton pencil beams are delivered from...
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Alejandro Carabe Fernandez
Keywords(s):
Oncology
,
Platform Technology
,
Radiology
Category(s):
Technology Classifications > Imaging
,
Technology Classifications > Medical Devices
Instant, Calibration-Free Blood-Flow Measurement With A Single Optical Snapshot
A single-frame, multi-exposure time optical method enabling accurate extraction of absolute speckle decorrelation time and optimized for recovery of absolute deep-tissue blood flow. Problem: Accurately recovering absolute speckle decorrelation time without the use of calibration or complex instrumentation is challenging. For the use case of monitoring...
Published: 1/8/2026
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Updated: 1/8/2026
|
Inventor(s):
Arjun Yodh
,
Wesley Baker
,
Joseph Majeski
,
Rodrigo Menezes Forti
Keywords(s):
Bioengineering
,
Cardiovascular
,
Electronic Materials
,
Gastroenterology
,
Internet of Things
,
Nephrology and Urology
,
Neurology
,
Oncology
,
Ophthalmology
,
Optics & Photonics
,
Platform Technology
,
Surgery
Category(s):
Technology Classifications > Computer Information Systems
,
Technology Classifications > Diagnostics
,
Technology Classifications > Digital Health
,
Technology Classifications > Hardware & Components
,
Technology Classifications > Imaging
,
Technology Classifications > Research Tools & Reagents
,
Technology Classifications > Medical Devices
,
Technology Classifications > Testing & Measurement
Anticancer IgG Against Multiple Epitopes on Live Tumors Upon Disruption of ‘Self’ Signaling by CD47
A method to combine two or three monoclonal antibodies (mABs) into one treatment to successfully bind to multiple cancer cell surface epitopes and promote targeted degradation by phagocytosis. Problem: Phagocytosis of ‘self’ cells is generally inhibited by a key macrophage checkpoint interaction between SIRPα on the macrophage and...
Published: 12/15/2025
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Updated: 12/15/2025
|
Inventor(s):
Dennis Discher
,
Jason Andrechak
,
Lawrence Dooling
Keywords(s):
Antibody
,
Bioengineering
,
Cell Therapy
,
Drug Target
,
Immunology
,
Immun
oncology
,
Immunotherapy
,
Oncology
,
Platform Technology
Category(s):
Technology Classifications > Therapeutics
Novel AKR1C3 Inhibitors in Cancer
Inhibitors and tools to block the local formation of steroid hormones in hormone-dependent malignancies of the prostate, breast and endometrium Value Proposition: Standard treatment of care for hormone-dependent tumors utilizes hormone ablative therapies. These agents non-discriminately block the action of estrogens and androgens and have untoward side...
Published: 10/30/2025
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Updated: 10/30/2025
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Inventor(s):
Trevor Penning
,
Adegoke Adeniji
,
Michael Byrns
,
Jeffrey Winkler
,
Barry Twenter
,
Lawrence Marnett
,
Andy Liedtke
Keywords(s):
Men's Health
,
Oncology
,
Small Molecule
,
Women's Health
Category(s):
Technology Classifications > Therapeutics
Profiling Chemically Modified DNA/RNA Units for Disease and Cancer Diagnosis
Diagnose a wide variety of conditions by analyzing DNA and RNA nucleotides/nucleosides. Background: In theory, RNA and DNA can be used to diagnose a broad range of diseases. Unfortunately, there are no existing technologies capable of providing comprehensive profiles of variant DNA/RNA components. Established approaches for the analysis/detection of...
Published: 1/30/2026
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Updated: 10/24/2025
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Inventor(s):
Daniele Fabris
,
Rebecca Rose
Keywords(s):
cancer
,
DNA modifications
,
epigenetics
,
genome-wide analysis
,
infection
,
oncology
,
RNA modifications
,
Technologies
Category(s):
Technology Classifications > Diagnostics
,
Campus > University at Albany
Decision Support Tool for Detection of Prostate Lesions on MRI
Prostate cancer diagnostic software that provides expert-level lesion detection, localization, automated segmentation, and automated report generation in less than 45 seconds. Background: According to the American Cancer Society, about 1 in 8 men will be diagnosed with prostate cancer during their lifetime. American Urologic Association guidelines...
Published: 9/25/2025
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Updated: 9/25/2025
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Inventor(s):
Thomas Sanford
,
Gennady Bratslavsky
Keywords(s):
magnetic resonance imaging
,
oncology
,
prostate
,
software
,
Technologies
Category(s):
Technology Classifications > Healthcare IT
,
Campus > Upstate Medical University
Treatment of viral induced cancers
Docket# S4039 Technology: Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus(KSHV) are human γ-herpesviruses associated with a broad spectrum of B-cell lymphomas typically in immune-compromised populations. There are no drugs which can specifically target EBV/KSHV-associated B-cell tumors. Using a High-throughput Screen...
Published: 8/7/2025
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Updated: 8/7/2025
|
Inventor(s):
Erle Robertson
Keywords(s):
Oncology
Category(s):
Technology Classifications > Therapeutics
Peptides For Solid Cancer Tumor Immunotherapy Treatment
Short, multivalent peptide antagonists to block macrophage immune-receptor SIRPα, promoting cancer cell phagocytosis. Problem: Modern cancer cell immunotherapies incorporate immune checkpoint blockade mechanisms, where prominent therapies target functionally suppressed immune cells in tumor microenvironments. Relieving this suppression allows...
Published: 9/17/2025
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Updated: 8/1/2025
|
Inventor(s):
Dennis Discher
,
AbdelAziz Jalil
Keywords(s):
Cell Therapy
,
Immunology
,
Oncology
Category(s):
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Therapeutics
,
Technology Classifications > Vaccines
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