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Search Results - martin+semmelhack
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Antibacterial Adjuvants for Pseudomonas Aeruginosa
Antibacterial Adjuvants for Reduced Cationic Antimicrobial Peptide Dosing and Combination TherapyPrinceton Docket # 20-3616-1 Researchers in the Department of Chemistry at Princeton University and the Department of Chemistry at San Jose State University have discovered compounds which increase the susceptibility of both CAP-resistant as well...
Published: 2/15/2023
|
Inventor(s):
Laura Conrad
,
Martin Semmelhack
,
Zinan Zhang
,
Minh Tran
,
Lauren Blankenship
Keywords(s):
antibiotics
Category(s):
Biotechnology/Pharmaceuticals
Double-Caged GABA: A Novel Light-Activated Probe as a Neuroscience Research Tool
Double-caged GABA: A Novel Light-activated Probe as a Neuroscience Research Tool Princeton Docket # 13-2896-1 Researchers at Princeton University, Departments of Molecular Biology and Chemistry, have developed a light-activated probe that can be used as a neuroscience research tool. Current methods of probing neural...
Published: 9/12/2024
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Inventor(s):
Diana Shi
,
Samuel Wang
,
Martin Semmelhack
Keywords(s):
Biotechnology/Pharmaceuticals
,
Chemistry
,
CNS
,
life science research tools
Category(s):
Biotechnology/Pharmaceuticals
,
Chemistry
Microfluidic Device for the Study and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices
Methods and Microfluidic Device for the Study, Testing and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices Docket # 13-2880Researchers at Princeton University have developed a microfluidic system and method to investigate biofilm morphologies under more realistic physical conditions which could be used to screen potential...
Published: 9/8/2022
|
Inventor(s):
Bonnie Bassler
,
Howard Stone
,
Martin Semmelhack
,
Knut Drescher
,
Yi Shen
,
Colleen O'loughlin
,
Laura Miller Conrad
Keywords(s):
antibiotics
,
anti-infectives
,
Biotechnology/Pharmaceuticals
,
life science research tools
,
medical device
Category(s):
Biotechnology/Pharmaceuticals
,
Medical Devices/Diagnostics
Novel Compounds for Treating Cholera and Other Infections: Potent Agonists of the Quorum Sensing Circuit
Princeton Dockets # 08-2418, 12-2775 & 12-2776 Cholera, an infection caused by the bacterium Vibrio cholerae, is a life-threatening disease. It is estimated that cholera affects 3-5 million people worldwide, and causes 100,000-130,000 deaths a year as of 2010. Antibiotics such as doxycycline and cotrimoxazole have been used to shorten the...
Published: 3/30/2022
|
Inventor(s):
Martin Semmelhack
,
Bonnie Bassler
,
Lark Perez
,
Megan Bolitho
,
Matthew Koch
,
Wai-Leung Ng
Keywords(s):
antibiotics
,
Biotechnology/Pharmaceuticals
,
small molecule
Category(s):
Biotechnology/Pharmaceuticals
Anti-Biofilm Compound 1 (ABC-1) and Associated Derivative Molecules
IntroductionBacteria commonly attach to living and nonliving surfaces in the form of biofilms. In this morphology, the bacteria synthesize a matrix of extracellular polymeric substances (EPS) that provide the biofilm with protection and structural support. The EPS also gives the biofilm resistance to antibiotics and immune system clearance, making biofilms...
Published: 11/21/2023
|
Inventor(s):
Christopher Waters
,
Karthik Sambanthamoorthy
,
Matthew Neiditch
,
Martin Semmelhack
Keywords(s):
Biofilm
,
Film
,
Pathogen
Category(s):
Biotechnology