Search Results - diabetes

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A NON-INVASIVE DIAGNOSTICS PLATFORM FOR MEASURING GLUCOSE LEVELS IN SALIVA
NU 2017-094 Inventors Vinayak P. Dravid* Vikas Nandwana Short Description A non-invasive diagnostic platform for detecting glucose in saliva. Background The glucometer is currently the state-of-the-art technology for at home glucose detection and is based on electrochemical analytics of blood samplings. Patients prick their finger and transfer...
Published: 5/25/2025   |   Inventor(s):  
Keywords(s): Devices, Diabetes, Diagnostics, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Bioresorbable, wireless, and battery-free electrotherapy system for wound healing and monitoring in diabetes
NU 2022-079 INVENTORS Guillermo Ameer* John Rogers* Joseph Woojin Song Han Jun Ryu SHORT DESCRIPTION A revolutionary bioresorbable, wireless, and battery-free electrotherapy system designed for effective wound healing and monitoring in diabetic patients. BACKGROUND Diabetes is a highly prevalent disease, affecting 1 in 3 Americans. Diabetes is associated...
Published: 5/9/2025   |   Inventor(s):  
Keywords(s): Diabetes, Electronics & Circuits, Materials, Medical device, Smart/Functional materials
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Small molecule inhibits the interaction between tristetraprolin and CNOT1 for therapeutic use in metabolic disorders
NU 2024-057 INVENTORS Hossein Ardehali* Jason Shapiro SHORT DESCRIPTION Compound that inhibits the interaction between tristetraprolin (TTP) and CCR4-NOT Transcription Complex Subunit 1 (CNOT1) offers potential therapeutic avenue for metabolic disorders by modulating mRNA degradation without inflammatory side effects. BACKGROUND Metabolic disorders...
Published: 5/5/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Diabetes, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Novel artificial neural network-based (ANN) approach for glycemic forecasting
Project ID: D2009-05 Background: Currently, glycemic control is obtained via point of care (POC) glucose monitoring and delivery of insulin based on a defined insulin infusion protocol. This discrete monitoring is disadvantageous as glucose concentrations are unknown when POC glucose values are not obtained. Neural network based models for real-time...
Published: 11/25/2024   |   Inventor(s): Brent Cameron, Scott Pappada
Keywords(s): CGM, Continuous glucose monitoring, Diabetes, Hyperglycemia
Category(s): Medical Device, Diagnostics
Sensitive and Selective Synthetic Glucose Receptor for Diagnostic Applications
Advantages: Highly sensitive glucose sensor with strong potential for use in biomedical diagnostics and continuous glucose monitoring. Flexible, adaptive binding pocket that selectively targets glucose’s functional groups, improving specificity and detection accuracy. Reversible, non-covalent binding to glucose, allowing real-time response...
Published: 5/5/2025   |   Inventor(s): Wenqi Liu
Keywords(s): Biotechnology, Diabetes, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical
Small Molecule Humanin Mimetics and Enhancers That Normalize Neuronal p-AKT as Novel Therapeutics for Alzheimer's Disease (UCLA Case No. 2023-230)
UCLA researchers in the Department of Neurology have discovered novel small molecule humanin mimetics for the treatment of Alzheimer's disease and other chronic conditions with dysregulated p-Akt. BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia accounting for 60-70% of all cases. Nearly 7 million Americans are living...
Published: 2/14/2025   |   Inventor(s): Varghese John
Keywords(s): Alzheimers disease, Cardiovascular, Cardiovascular Disease, Dementia, diabetes, mimetics, pAKT signaling, small molecules
Category(s): Therapeutics > CNS and Neurology, Therapeutics > Cardiovascular
Localized In Vivo Electro Gene Therapy for Type 1 Diabetes
­Advantages: Novel gene therapy for Type 1 Diabetes (T1D) focused on reprogramming skeletal muscle cells to modulate glucose levels in vivo. Nano plasmid DNA of insulin and glucokinase decreased glucose levels in vitro and in vivo and enhanced insulin expression and secretion. Groundbreaking treatment for long-lasting blood glucose control...
Published: 1/14/2025   |   Inventor(s): Anna Bulysheva
Keywords(s): Diabetes, Medical Therapeutics Gene Therapy
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 2/13/2025   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Nishant Visavadiya
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 2/13/2025   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Indrajit Bandyopadhyay
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine, Neurodegenerative Disorders, Parkinson's Disease, Pharmaceutical
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Novel Human Insulin Cα-Peptide as an Antagonist for Islet and Brain Amyloidosis
Abstract: Over 32 million Americans are living with Diabetes and newly diagnosed cases of type 1 and type 2 diabetes is increasing. A defining feature of type 2 diabetes mellitus (T2DM) is the accumulation of islet amyloid polypeptide (IAPP) fibrils in pancreatic islets. Such accumulations form amyloid plaques, referred to as islet amyloidosis. Mounting...
Published: 4/22/2025   |   Inventor(s): Qing Rong Liu, Min Zhu, Pingbo Zhang, Josephine Egan, Luigi Ferrucci
Keywords(s): Alzheimer’s Disease, Amyloidosis, C-peptide, DIABETES, Egan, insulin, Islet Amyloid Polypeptide, Liu, National Institute on Aging, NIA
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Endocrinology
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