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Search Results - robert+prud%27homme
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Amphiphilic Polymer Stabilized Nanoparticles with Enhanced Biological Stability and Activity
Experimental oxLDL macrophage cellular uptake results after 24-hr incubation with AM micelle or NP configurations under serum free conditions (white bars), 5% FBS (gray bars) and 20% FBS (black bars). Invention Summary: According to Centers for Disease Control and Prevention nearly 25% of deaths in the US is due to cardiovascular...
Published: 4/17/2024
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Inventor(s):
Kathryn Uhrich
,
Prabhas Moghe
,
Adam York
,
Robert Prud'homme
Keywords(s):
Biomaterials
,
Cardiovascular
,
Drug Delivery
,
Nanoparticles
,
Polymers & Composites
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Therapeutics
Sequential Multi-Step Flash Nanoprecipitation for the Formation of Small Nanoparticles with High Core Loading
Flash NanoPrecipitation for Preparing High Capacity NanoparticlesPrinceton Docket # 20-3636 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new Flash NanoPrecipitation process, to form nanoparticles with high loadings. The new process, synthesizes nanoparticles with core loadings as...
Published: 9/6/2022
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Inventor(s):
Leon Wang
,
Kurt Ristroph
,
Robert Prud'homme
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
Efficient Encapsulation of Hydrophilic Biologics into Nanocarriers
Efficient Encapsulation of Hydrophilic Biologics into NanocarriersPrinceton Docket # 18-3414-1The research team at Princeton University has demonstrated a novel and efficient method to encapsulate highly water-soluble biologic active pharmaceutical ingredients into nanocarriers using a single precipitation step.Nanoprecipitation of active pharmaceutical...
Published: 6/5/2023
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Inventor(s):
Robert Prud'homme
,
Kurt Ristroph
,
Nathalie Pinkerton
,
Hoang (Jack) Lu
,
Paradorn Rummaneethorn
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
An Economical Design and Processing of Lipophilic Drugs for Fast-Releasing Water Dispersible Formulations
An Economical Design and Processing of Lipophilic Drugs for Fast-Releasing Water Dispersible FormulationsPrinceton Docket # 18-3396-1The Prud’homme group has developed a novel, economical, and scalable formulation and process to prepare nanoparticles from poorly water soluble drugs in order to improve oral bioavailability and dissolution rate...
Published: 12/22/2023
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Inventor(s):
Jie Feng
,
Kurt Ristroph
,
Hoang Lu
,
Yingyue Zhang
,
Simon McManus
,
Robert Prud'homme
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction
Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction Princeton Docket #14-3014 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....
Published: 4/19/2022
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Inventor(s):
Rodney Priestley
,
Robert Prud'homme
,
Rui Liu
,
Chris Sosa
Keywords(s):
catalyst
,
Chemistry
,
drug delivery
,
energy
,
Imaging
,
nanotechnology
Category(s):
Chemistry
Scalable, Highly Immunogenic, Polysaccharide-Peptide Nanoparticle Vaccine for Protection against Many Bacterial Serotypes
Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...
Published: 7/18/2024
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Inventor(s):
Nikolas Weissmueller
,
Robert Prud'homme
,
Ruth Rosenthal
Keywords(s):
anti-infectives
,
drug delivery
,
nanotechnology
,
vaccines
Category(s):
Biotechnology/Pharmaceuticals
Highly loaded (Depot) Microparticle Delivery System for the Controlled Release of Aqueous Soluble Biologics and Therapeutics
Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...
Published: 6/20/2024
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Inventor(s):
Robert Pagels
,
Robert Prud'homme
,
Chester Markwalter
Keywords(s):
Chemistry
,
drug delivery
,
Imaging
Category(s):
Biotechnology/Pharmaceuticals
,
Medical Devices/Diagnostics
Nano-Encapsulation Using GRAS Materials
Nanoparticle Compositions and Methods using Gras Materials for encapsulation and delivery of active pharmaceutical ingredients Princeton Docket # 15-3169Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nano-encapsulation process using generally recognized as safe (GRAS) material. Through...
Published: 6/20/2024
|
Inventor(s):
Nikolas Weissmueller
,
Robert Prud'homme
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
Enhanced Adjunctive Therapies for Microbial Infections and Imaging
Princeton Docket # 16-3183-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a nanocarrier based approach to enable and enhance adjunctive therapies for microbial infections by simultaneous encapsulation and delivery of all components.Microbial infections have become increasingly difficult to...
Published: 9/11/2024
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Inventor(s):
Robert Prud'homme
,
Hoang Lu
Keywords(s):
antibiotics
,
drug delivery
,
Imaging
,
nanotechnology
Category(s):
Biotechnology/Pharmaceuticals
Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging Agents
Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging AgentsPrinceton Docket # 14-3045The encapsulation and controlled release of peptides and bio-active materials is a significant challenge in the nanoparticle field. Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a novel...
Published: 3/17/2023
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Inventor(s):
Robert Pagels
,
Robert Prud'homme
Keywords(s):
biologics
,
nanotechnology
,
research tool
Category(s):
Chemistry
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