Search Results - biotechnology

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The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses
Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon...
Published: 9/6/2024   |   Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen
Keywords(s): Biomedical, Human Health, Pharma, Research, Veterinary Medicine
Category(s): Biotechnology, Biomedical, Pharma, Veterinary Medicine
Reagents, Devices, and Accessories for Kinetic Fluorogenic Chemical Quantification
Background Kinetic chromogenic (CG) and fluorogenic (FG) quantification deduces analyte concentration based on the reaction rate between the CG/FG probe and its targeted molecule. Little progress has been made in the past half century in either the theory or the applications of the kinetic spectroscopic quantification methods. Current kinetic CG/FG...
Published: 9/6/2024   |   Inventor(s): Dongmao Zhang, Max Wamsley
Keywords(s): Biomedical, Chemicals, Food, Instruments, Materials, Military or Defense, Research
Category(s): Biomedical, Materials, Instruments, Biotechnology, Agriculture & Food Science
mRNA Treatment to Induce Expression of Molecules to Prevent or Treat Tritrichomonas Foetus Infection in Bulls
Background Bulls and cows are susceptible to reproductive system infection by the protozoal parasite Tritrichomonas foetus (T. foetus). Infected cows are unable to deliver healthy calves, and they can become infected by bulls that, despite showing no signs of the disease, are capable of transmitting the infection to cows. The failure of cows to deliver...
Published: 9/6/2024   |   Inventor(s): Amelia Woolums, Elmer King, Merrilee Thoresen
Keywords(s): Veterinary Medicine
Category(s): Veterinary Medicine, Biotechnology
A Method for Targeting Nanoparticles to Bacterial Biofilm Infections using Bacterial Surface Proteins
Background Biofilm‑related infections are associated with high mortality and morbidity, combined with increased hospital stays and overall treatment costs. Traditional antibiotics play an essential role in controlling biofilms; however, they are becoming less effective due to the emergence of drug‑resistant bacterial strains. The need to treat biofilms...
Published: 9/6/2024   |   Inventor(s): Nicholas Fitzkee, Dhanush Amarasekara
Keywords(s): Human Health, Materials, Medical Devices, Military or Defense, Nanotechnology and Nanoscience
Category(s): Biomedical, Biotechnology, Materials, Medical Devices, Pharma
mRNA Therapy to Induce Expression of Molecules to Prevent or Treat Infectious Respiratory Disease in Cattle
Background Infectious respiratory disease in cattle is the most common cause of sickness and death in many types of cattle in the United States and around the world. It is caused by one or more of multiple different viruses and/or bacteria. Technology Overview Bovine respiratory disease (BRD) is the leading cause of sickness and death in many types...
Published: 9/5/2024   |   Inventor(s): Amelia Woolums
Keywords(s): Veterinary Medicine
Category(s): Veterinary Medicine, Biotechnology
mRNA Treatment to Induce Expression of Relaxin for Reproductive Applications in Animals and Humans
Background Female cattle and other animals, including humans, sometimes have trouble delivering their young (dystocia) at the time they are due because of inadequate relaxation or size of the mother's reproductive tract. Such situations can lead to difficult deliveries that may be harmful to the mother or the offspring. They may also require surgery...
Published: 9/9/2024   |   Inventor(s): Peter Ryan, Amelia Woolums, Elmer King, Merrilee Thoresen, Federico Hoffmann
Keywords(s): Human Health, Veterinary Medicine
Category(s): Biotechnology, Veterinary Medicine
Spectroscopic Bioagent Detection
VALUE PROPOSITION The need for Identifying viruses quickly and accurately has become more apparent than ever. Each cell, virus, nanoparticle vibrates at a natural frequency. This technology is a phonon spectroscopy-based microscope that accurately identifies single nanoparticles and viruses. The device can be used for detecting single viruses or...
Published: 9/24/2024   |   Inventor(s): Elad Harel
Keywords(s):  
Category(s): Medical, Analytical Instruments, Biotechnology, Environmental, Photonics
Therapeutic for Tissue Healing and Resistive Bacteria
INTRODUCTION Healing infected tissue and combating resistant bacteria are significant clinical challenges. Antibiotic-based therapies are increasingly unsuccessful due to the ability of pathogens to develop resistance. Methicillin resistant Staphylococcus aureus (MRSA), for example, is a leading cause of many infections, including skin and soft tissue...
Published: 8/5/2024   |   Inventor(s): Xanthippi Chatzistavrou, Neal Hammer
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical
MRI RF Powered Voltage Sensor
VALUE PROPOSITION For Magnetic Resonance Imaging it is often desirable to measure electrophysical characteristics alongside MRI data. To do so, voltage sensors are employed. This technology is an RF powered voltage sensor which can be configurable to measure a variety of physical indicators with excellent resolution. The design minimizes interference...
Published: 7/29/2024   |   Inventor(s): Chunqi Qian
Keywords(s):  
Category(s): Medical, Test and Measurement, Biotechnology
Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use
Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use Executive Summary: Well-characterized non-genetically modified bovine primary muscle cell lines have been sorted based on genetic information and proliferate well for research use. Background: Animal cell lines are utilized for a variety of medical and veterinary...
Published: 5/6/2024   |   Inventor(s): Jongkyoo Kim
Keywords(s):  
Category(s): Agricultural, Agriculture, Animal/Veterinary, Biotechnology, Veterinary, Therapeutic
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