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Dual-Action-Only Proteolysis Targeting Chimeras

PRODUCT OPPORTUNITIES Targeted protein degradation platform Precision therapeutics PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Selectivity Reduced off-target toxicity Platform versatility and compatibly with established PROTAC approaches TECHNOLOGY DESCRIPTION This invention demonstrates an AND-logic gated Proteolysis...

Published: 8/5/2026 | Updated: 8/5/2026 | Inventor(s): Sankaran Thayumanavan, Ranit Dutta

Keywords(s):

Category(s): Biotechnology, Healthcare, Life Sciences, Therapeutics & prevention

LASER SYSTEM FOR BLOOD OR TISSUE ASSESSMENT

VALUE PROPOSITION It is useful in multiple situations to provide rapid, accurate, and non-invasive blood health assessments. A portable, cost-effective, and user-friendly solution is desired to enhance patient care and safety across various medical settings, from hospitals and clinics to emergency services and disaster relief scenarios. Its potential...

Published: 7/7/2026 | Updated: 7/7/2026 | Inventor(s): Marcos Dantus

Keywords(s):

Category(s): Biotechnology, Devices, Analytical Instruments, Test and Measurement

CENTRAL BLOOD PRESSURE MONITORING

VALUE PROPOSITION Automatic arm cuff devices provide non-invasive, convenient, and clinically valuable blood pressure monitoring. These devices offer a high level of accuracy, ensuring reliable data collection and analysis. They are cost-effective, as they eliminate the need for frequent visits to healthcare facilities for blood pressure checks. Moreover,...

Published: 7/6/2026 | Updated: 7/6/2026 | Inventor(s): Ramakrishna Mukkamala, Keerthana Natarajan, Jin-Oh Hahn

Keywords(s):

Category(s): Medical, Biotechnology

MONITORING PATIENTS FOR AORTIC ANEURYSMS

VALUE PROPOSITION Aortic aneurysm, which are potentially life-threatening bulges in the aorta, often go unnoticed until it reaches a critical stage. By enabling early detection, healthcare providers may intervene promptly, potentially saving lives and reducing the risk of catastrophic rupture. Cost-effectiveness and scalability are important for widespread...

Published: 7/1/2026 | Updated: 7/1/2026 | Inventor(s): Ramakrishna Mukkamala, Mohammad Yavarimanesh, Jin-Oh Hahn

Keywords(s):

Category(s): Medical, Biotechnology

Multiplexing, signal rechanneling and optical powered oscillator

VALUE PROPOSITION For Magnetic Resonance Imaging it is often desirable to measure electrophysical characteristics alongside MRI data. To do so, voltage sensors are employed. This technology is an RF powered voltage sensor which can be configurable to measure a variety of physical indicators with excellent resolution. The design minimizes interference...

Published: 6/30/2026 | Updated: 6/30/2026 | Inventor(s): Chunqi Qian

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Category(s): Medical, Biotechnology

COMPUTED TOMOGRAPHY AND ADDITIVELY MANUFACTURED BIOMATERIAL IMPLANT

VAlue proposition The use of implantable biomedical tissue engineering scaffolds (TES) in the clinic is growing rapidly. Often, TES are engineered to perform critical functions in regenerative medicine, including providing mechanical support, delivering therapeutic molecules, and creating protective barriers. Clinically approved TES for these purposes...

Published: 1/9/2026 | Updated: 1/9/2026 | Inventor(s): Kendell Pawelec, Erik Shapiro, James Siegenthaler

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Category(s): Medical, Biotechnology

Antimicrobial bioactive glass-ceramic scaffold

Executive Summary Healing infected tissue and combating resistant bacteria are significant clinical challenges. Antibiotic-based therapies are increasingly unsuccessful due to the ability of pathogens to develop resistance. Methicillin resistant Staphylococcus aureus (MRSA), for example, is a leading cause of many infections, including skin and soft...

Published: 12/1/2025 | Updated: 12/1/2025 | Inventor(s): Xanthippi Chatzistavrou, Neal Hammer

Keywords(s):

Category(s): Medical, Biotechnology, Pharmaceutical

Demineralized Bone Paper and Applications Thereof

PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...

Published: 4/20/2026 | Updated: 10/1/2025 | Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak

Keywords(s):

Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention

An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease

PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...

Published: 9/25/2025 | Updated: 9/25/2025 | Inventor(s): Lisa Minter, Gregory Tew, Emrah Ozay

Keywords(s):

Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Therapeutics & prevention

Novel Targets and Compounds to Treat Bladder Cancer

Alternative splicing modulating antisense oligonucleotides (ASOs) targeting novel identified alternative splicing changes associated with RBM10 mutations in bladder cancer. We are developing lead ASOs to treat bladder, and eventually other, cancers. Technology: Bladder cancer is the 9th most common malignant disease worldwide and 13 most frequent...

Published: 8/6/2025 | Updated: 8/6/2025 | Inventor(s): Juan Valcarcel, Ángel Guerra, Tobias Hoffmann

Keywords(s):

Category(s): Biotechnology, Drug Targets & Mechanisms, Therapeutics (Biologics & Compounds)

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