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Search Results - alexander+ploss
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A Genetically Humanized Mouse for Preclinical Testing of Specific Reagents Targeting Human CD81 and/or Human Occludin and for the Study of B Cell Lymphoma and Hepatitis C
A Genetically Humanized Mouse for Preclinical Testing of Specific Reagents Targeting Human CD81 and/or Occludin for study of B cell Lymphoma and Hepatitis C Docket# 19-3577-1The tetraspanin CD81, which is part of the B cell receptor complex, has emerged as an important immunotherapeutic target for treating B cell lymphoma. Researchers at Princeton University...
Published: 2/15/2024
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Inventor(s):
Alexander Ploss
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika Viruses
Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika VirusesPrinceton Docket # 18-3474Researchers in the Department of Molecular Biology have discovered a human host factor that is required for effective yellow fever virus (YFV) infection of human cells. This molecule is unlike anything, in both structure and...
Published: 2/14/2024
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Inventor(s):
Alexander Ploss
,
Florian Douam
,
Qiang Ding
Keywords(s):
Category(s):
Biotechnology/Pharmaceuticals
Novel Cell Line for Hepatitis B Drug Discovery and Research
Novel Cell Line for Hepatitis B Drug Discovery and Research Princeton Docket # 15-3077 Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...
Published: 2/14/2024
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Inventor(s):
Alexander Ploss
,
Benjamin Winer
Keywords(s):
anti-infectives
,
anti-viral
,
biomarker/diagnostic
,
Biotechnology/Pharmaceuticals
,
infectious disease
,
life science research tools
,
research tool
,
therapeutic
,
vaccines
,
virology
Category(s):
Biotechnology/Pharmaceuticals