Search Results - alexander+ploss

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Development of a dual channel detection system for pan-genotypic simultaneous quantification of hepatitis B and delta viruses
Development of a dual channel detection system for pan-genotypic simultaneous quantification of hepatitis B and delta viruses Princeton Docket: 24-4106-1 Hepatitis B virus (HBV) remains a major public health problem, causing chronic infection in at least 257 million people who are at risk of developing severe liver disease, including fibrosis,...
Published: 10/9/2024   |   Inventor(s): Alexander Ploss, Yongzhen Liu
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals
A Genetically Humanized Mouse for Preclinical Testing of Specific Reagents Targeting Human CD81 and/or Human Occludin and for the Study of B Cell Lymphoma and Hepatitis C
A Genetically Humanized Mouse for Preclinical Testing of Specific Reagents Targeting Human CD81 and/or Occludin for study of B cell Lymphoma and Hepatitis C Docket# 19-3577-1The tetraspanin CD81, which is part of the B cell receptor complex, has emerged as an important immunotherapeutic target for treating B cell lymphoma. Researchers at Princeton University...
Published: 2/15/2024   |   Inventor(s): Alexander Ploss
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals
Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika Viruses
Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika VirusesPrinceton Docket # 18-3474Researchers in the Department of Molecular Biology have discovered a human host factor that is required for effective yellow fever virus (YFV) infection of human cells. This molecule is unlike anything, in both structure and...
Published: 2/14/2024   |   Inventor(s): Alexander Ploss, Florian Douam, Qiang Ding
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals
Novel Cell Line for Hepatitis B Drug Discovery and Research
Novel Cell Line for Hepatitis B Drug Discovery and Research Princeton Docket # 15-3077 Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...
Published: 2/14/2024   |   Inventor(s): Alexander Ploss, Benjamin Winer
Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology
Category(s): Biotechnology/Pharmaceuticals