Search Results - antibiotic+resistant+bacteria

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System for Reversible Control of Morphotype Switching in Mycobacterium abscessus for Enhanced Disease Modeling and Therapeutic Research
Invention Description Antibiotic-resistant nontuberculous mycobacteria (NTM) infections are increasing at ~8% annually, placing a significant burden on healthcare systems. Mycobacterium abscessus (Mabs) represents one of the most treatment-refractory pathogens, particularly in cystic fibrosis (CF) patients. Mabs disease severity is strongly associated...
Published: 2/26/2026   |   Inventor(s): Shelley Haydel, Rodrigo Aguilera Olvera, Lexi Yakimovich
Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, CRISPR-Cas, Gene Expression, Infectious Disease, Microbes, bacteria, fungi, virus, yeast, Microbiology, Mycobacteria, mycobacterial genetics, Pathogen
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Nucleic Acid/Peptide/Protein Therapies
Sweat as a Biofluid for Analysis and Disease Identification
Noninvasive sampling is critical for certain patient populations, such as hemophiliacs, neonates, elderly or immunocompromised individuals, especially if they require daily monitoring. Blood sampling is painful, inconvenient and often difficult and increases the risk of exposure to infectious agents, which can be devastating to immunocompromised populations....
Published: 2/26/2026   |   Inventor(s): Benjamin Katchman, Karen Anderson, Jennifer Blain Christen
Keywords(s): Antibiotic Resistant Bacteria, Antibodies, Autoantibody, biomarker, Defense/military, Diagnostics, Sweat
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Antibacterial Peptides, Synbodies, and Methods of Discovery
Antibiotic resistance is a worldwide clinical and public health problem, primarily stemming from the overuse of antibiotics. One of the most critical resistant pathogens is Methicillin-resistant Staphylococcus aureus (MRSA), which accounts for over 2,000,000 illnesses and 11,000 deaths each year. MRSA has developed resistance to all beta-lactam antibiotics....
Published: 2/26/2026   |   Inventor(s): Chris Diehnelt, Stephen Johnston, Pamela Hall
Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, Antibiotics, Anti-Infectives, Drug Discovery, Infectious Disease, Peptides, Therapeutics
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools, Pharmaceuticals, Vaccines/Antimicrobials
Antibiotic Susceptibility Testing
Antibiotic-resistant bacterial infections cost billions of dollars to the US in healthcare and result in 2 million hospitalizations and 23,000 deaths. Clinical treatment of bacterial infections, especially in acute cases of sepsis, requires multiple steps, including antibiotic susceptibility tests (AST). Current AST techniques are slow and limited to...
Published: 2/13/2025   |   Inventor(s): Nongjian (nj) Tao, Karan Syal
Keywords(s): Antibiotic Resistant Bacteria, Antibiotics, Antibodies, Antibody Therapeutics, Anti-Infectives
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Imaging, Life Science (All LS Techs), Medical Diagnostics/Sensors