Search Results - anti-inflammatory

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Thalidomide Analogs that Inhibit Inflammation and Angiogenesis
Abstract: Thalidomide and its close analogs (lenalidomide and pomalidomide) are widely used to treat a variety of diseases, such as multiple myeloma and other cancers as well as the symptoms of several inflammatory disorders. However, thalidomide is known for its teratogenic adverse effects when first clinically introduced in the 1950s, and is associated...
Published: 4/8/2024   |   Inventor(s): Nigel Greig, Weiming Luo, David Tweedie, Nell Vargesson, Shaunna Beedle, William Figg
Keywords(s): anti-angiogenesis, ANTI-INFLAMMATORY, Lenalidomide, Pomalidomide, THALIDOMIDE
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
NAG-1: A Non-Steroidal Anti-Inflammatory Drug Related Gene Which Has Anti-Tumorigenic Properties
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of inflammatory disease, and their anti-inflammatory effects are believed to result from their ability to inhibit the formation of prostaglandins by prostaglandin H synthase (COX). Two forms of prostaglandin H have been identified, COX-1 and COX-2. The former seems to...
Published: 10/28/2024   |   Inventor(s): Richard Diaugustine, Baek Seung, Thomas Eling
Keywords(s): ANTI-INFLAMMATORY, Anti-Tumorigenic, CAXXXX, CBXXXX, CXXXXX, Diagnostics, DRUG, Duke DNA Project, GAXXXX, GBXXXX, Gene, GXXXXX, NAG-1, Non-Steroidal, Patent Category - Biotechnology, PROPERTIES, Protein, RELATED, screening, SECRETED, That, therapeutics
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Oncology
Natural Compounds for Modulation of Cell Secretome Production and Composition
Reference #: 01421 The University of South Carolina is offering licensing opportunities for Natural Compounds for Modulation of Cell Secretome Production and Composition Background: Plants are the oldest source of natural compounds with medicinal and cosmetic properties explored by the world. 11% of the existed essential drugs used in modern human...
Published: 8/9/2023   |   Inventor(s): Ehsan Jabbarzadeh, Maria Yanez, Sara Eslambolchimoghadam
Keywords(s): anti-inflammatory, anti-inflammatory biotech, anti-inflammatory pharma, catalyzing stem cell secretome, cell-free therapy, chronic wound treatment, condition media, natural, Natural product, regenerative therapy
Category(s): Biomedical and Life Sciences, Health Sciences
Therapeutic Compounds to Enhance Cognition, Counteract Depression and Treat Smoking Addiction
Chemicals Selectively Modulate Cell Receptors Linked to Neurological Disorders in Humans and Other MammalsThese compounds enable effective treatment of neurological disorders involving cognitive deficits (including Alzheimer’s and Parkinson’s diseases), depression and drug dependences such as tobacco (nicotine) and betel nut addictions....
Published: 6/27/2021   |   Inventor(s): William Kem, Ferenc Soti, Hong Xing
Keywords(s): Alzheimer's Disease, Anti-Inflammatory, Cognition Enhancer, Dementia, Parkinson's Disease, Post Traumatic Stress Disorder, Schizophrenia, Wound Healing
Category(s): Technology Classifications > Human Health Care > Therapeutics
Non-Opioid-Based Anti-Inflammatory Medication
Compounds Modulate Inflammatory Responses in Human Cells and Reduce Pain Response in MiceThis therapeutic compound reduces inflammation without opioid-based pharmacology, offering pain relief without the threat of addiction and showing potential for neurocognition processes. Inflammation is associated with a number of disease states and physiologic...
Published: 8/24/2021   |   Inventor(s):  
Keywords(s): Anti-Inflammatory, Inflammation Reduction, nicotinic acetylcholine
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Therapeutics
A Functional Monoclonal Antibody Against DC-STAMP
Brief Description: Bone is a very dynamic organ as evidenced by the process of bone remodeling which relies on a delicate balance between bone formation and bone resorption and is orchestrated by osteoblasts (OB) and osteoclasts (OC). The coordinated interplay of OB and OC continuously remodels bone through highly regulated molecular and cellular...
Published: 10/28/2024   |   Inventor(s): Kofi Mensah, Yahui Grace Chiu, Christopher Ritchlin, Edward Schwarz
Keywords(s): Antibody, Anti-inflammatory, Inflammation, Orthopaedics, Osteoporosis, Reagent
Category(s): Research Tools
Novel Isoselenazolone Derivatives Show Effectiveness Against Multiple Human Disease-causing Pathogens
Project ID: D2015-17Invention Description:Neurodegenerative, inflammatory and other physiological diseases are linked to the activity of reactive oxygen species (ROS). Glutathione peroxidase is a Selenium-based enzyme that has been shown to protect biomembranes and other cellular components from damage caused by ROS, by scavenging hydrogen peroxide...
Published: 6/18/2024   |   Inventor(s): Steven Sucheck, Donald Ronning, Sandeep Thanna, Alexander Landgraf
Keywords(s): Antibiotics, Anti-inflammatory, Antioxidant, Bipolar, Cancer, Cytoprotective, Hearing, Neurodegenerative, Reperfusion, Stroke
Category(s): Inflammation & Immunity