Search Results - schizophrenia

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Methods of making and using dopamine receptor selective antagonists/partial agonists
Abstract: Dopamine is a major neurotransmitter in the central nervous system and among other functions is directly related to the rewarding effects of drugs of abuse.  Dopamine signaling is mediated by D1, D2, D3, D4 and D5 receptors.  The dopamine D3 receptor is a known target to treat a variety of neuropsychiatric disorders, including substance use...
Published: 4/8/2024   |   Inventor(s): Amy Newman, Vivek Kumar, Anverbasha Shaik
Keywords(s): Bipolar Disorder, Cannabis, DEPENDENCE, dopamine D3 receptor, drug addiction, oxycodone, SCHIZOPHRENIA
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology, Application > Therapeutics
A Mouse Model for Mental Disorders and Epilepsy
Current State of the Art The Neuregulin/ErbB4 signaling pathway is involved in GABAergic neurotransmission, an important inhibitory neurotransmission that regulates several processes in the central nervous system including muscle tone. Aberrant GABAergic function has been implicated in Schizophrenia, Schizo-affective disorder and in Epilepsy....
Published: 4/29/2020   |   Inventor(s): Lin Mei, Wen-Cheng Xiong
Keywords(s): Drug Discovery, Drug Testing, Epilepsy, Mouse, Schizophrenia
Category(s): Research Tools
Therapeutic Compounds to Enhance Cognition, Counteract Depression and Treat Smoking Addiction
Chemicals Selectively Modulate Cell Receptors Linked to Neurological Disorders in Humans and Other MammalsThese compounds enable effective treatment of neurological disorders involving cognitive deficits (including Alzheimer’s and Parkinson’s diseases), depression and drug dependences such as tobacco (nicotine) and betel nut addictions....
Published: 6/27/2021   |   Inventor(s): William Kem, Ferenc Soti, Hong Xing
Keywords(s): Alzheimer's Disease, Anti-Inflammatory, Cognition Enhancer, Dementia, Parkinson's Disease, Post Traumatic Stress Disorder, Schizophrenia, Wound Healing
Category(s): Technology Classifications > Human Health Care > Therapeutics