Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - that
16975
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
First in class Small Molecule Agonists of the mammalian Relaxin family receptor 1 (RXFP1) and use in treatment of cancer, fibrotic, and vascular disorders (HHS Ref No. E-145-2024-0-US-02)
It is well documented in literature
that
activation of RXFP1 by relaxin induces: 1) up-regulation of the endothelin system which leads to vasodilation; 2) extracellular matrix remodeling through regulation of collagen deposition, cell invasiveness, proliferation, and overall tissue homeostasis; 3) a moderation of inflammation by reducing levels of inflammatory...
Published: 5/29/2025
|
Inventor(s):
Juan Marugan
,
Mark Henderson
,
Kenneth Wilson
,
Wenwei Huang
,
Wenjuan Ye
,
Noel Southall
,
Jiankang Jiang
,
Khalida Shamim
,
Bing Li
,
Alexander Agoulnik
,
Abhijeet Kapoor
,
Joshua Hutcheson
,
Ana Cabrera
,
Irina Agoulnik
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Research Materials
,
TherapeuticArea > Oncology
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Pulmonology
,
TherapeuticArea > Dermatology
,
TherapeuticArea > Reproductive Health
,
TherapeuticArea > Geriatrics
Wireless Sensors for Breast Milk Monitoring
NU 2024-030 INVENTORS John Rogers* Craig Garfield Matthew Grayson Jihye Kim Seyong Oh Daniel Robinson Jennifer Wicks Jaeyoung Yoo SHORT DESCRIPTION A compact, wireless, wearable bioimpedance sensor system for real-time monitoring of breast milk volume during breastfeeding. BACKGROUND Traditional methods for assessing milk intake rely...
Published: 5/29/2025
|
Inventor(s):
Keywords(s):
Category(s):
Life Sciences > Healthcare Devices, Tools & IT
BAC Transgenic Prox1CreERT2 Mouse Line: Allows for Deletion of 'Floxed' Genes Specifically in the Lymphatic Vasculature
Advantages Distinct BAC backbone allows for transgene integration on a separate chromosome, avoiding linkage and complex breeding schemes observed in current strains. Demonstrates >90% Cre-mediated excision in Prox1+ lymphatic endothelial cells, outperforming previous models which demonstrate ~60-70%. Restricts recombination to lymphatic vasculature...
Published: 5/29/2025
|
Inventor(s):
Joshua Scallan
Keywords(s):
Animal Models
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
DGR-MIL: Diverse Global Representation in Multiple Instance Learning
Histological whole slide image (WSI) processing techniques are critical for identifying and classifying tissues, particularly cancerous tissues. AI-aided methods for analyzing these WSIs have become increasingly important to enhance diagnostic precision and high throughput processing. However, WSIs have gigapixel resolution, leading to computational...
Published: 5/28/2025
|
Inventor(s):
Wenhui Zhu
,
Xiwen Chen
,
Peijie Qiu
,
Yalin Wang
,
Aristeidis Sotiras
,
Abolfazl Razi
Keywords(s):
Category(s):
Artificial Intelligence/Machine Learning
,
Computing & Information Technology
,
Imaging
,
Life Science (All LS Techs)
Mouse Models for Studying Hyperglycemia-induced Hyperfiltration via NOS1 and NKCC2 Proteins (NOS1Cre / NKCC2ftox / NOS1Cre-NKCC2ftox Mice)
Advantages Future applications for treatment of diabetic nephropathy Three mouse models for utilization in diabetic research Defined mechanism behind glomerular hyperfiltration Summary Our inventors have discovered a novel mechanism of hyperglycemia-induced hyperfiltration via the NOS1 and NKCC2 proteins within the body. By increasing the level...
Published: 5/28/2025
|
Inventor(s):
Ruisheng Liu
Keywords(s):
Animal Models
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Mouse Models for Studying Hyperglycemia-induced Hyperfiltration via NOS1 and NKCC2 Proteins (NOS1Cre / NKCC2ftox / NOS1Cre-NKCC2ftox Mice)
Advantages Future applications for treatment of diabetic nephropathy Three mouse models for utilization in diabetic research Defined mechanism behind glomerular hyperfiltration Summary: Our inventors have discovered a novel mechanism of hyperglycemia-induced hyperfiltration via the NOS1 and NKCC2 proteins within the body. By increasing the level...
Published: 5/28/2025
|
Inventor(s):
Ruisheng Liu
Keywords(s):
Animal Models
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Glycosylated RNA in Exosome Extracellular Vesicles
Overview of experimental approach used to demonstrate exosome-mediated intercellular transfer of glycoRNAs Invention Summary: Exosomes play a significant role in diverse cellular functions and responses. These structures are believed to furnish cells with a signaling mechanism facilitated by the cargo enclosed within the exosome. This cargo...
Published: 5/28/2025
|
Inventor(s):
Megerditch Kiledjian
,
Sunny Sharma
,
Xinfu Jiao
Keywords(s):
Category(s):
Technology Classifications > Therapeutics
,
Technology Classifications > Gene Therapy
Multi-Object Grasping -- Grasping from Surface of Pile
Advantages: High Efficiency in Cluttered Environments Vision-Guided Dexterity with 6D Pose Estimation Confidence-Driven Grasp Optimization Adaptive to Real-World Variability Scalable for Industrial Automation Summary: Robotic grasping in industries like manufacturing, warehousing, and logistics is still a bottleneck when dealing with dense...
Published: 5/28/2025
|
Inventor(s):
Tianze Chen
,
Yu Sun
Keywords(s):
Robotics
Category(s):
Technology Classifications > Engineering > Chemical Engineering
,
Technology Classifications > Engineering > Mechanical Engineering
,
Technology Classifications > Engineering > Industrial Engineering
Using Audible EEGs for Assisting in Brain Disease Diagnosis
This technology makes electroencephalogram (EEG) recordings audible to hear differences in real time by putting the filtered waves through an algorithm. This allows specialists to better identify where brain activity is different in real time rather than through visual analysis, which may take longer and may be harder to capture. Background: Currently,...
Published: 5/28/2025
|
Inventor(s):
Tally Milnes
,
Matthew Flowers
,
Cynthia Stokes
,
Michael Vince
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Creative Works
,
Technology Classifications > Life Sciences > Diagnostics
Methods and considerations for estimating parameters in biophysically detailed neural models with simulation based inference
Methods and considerations for estimating parameters in biophysically detailed neural models with simulation based inference Overview Biophysically detailed neural models are powerful tools for bridging scales in neuroscience, linking cellular and circuit-level mechanisms to macro-scale signals like EEG/MEG. These models incorporate ion channels,...
Published: 5/28/2025
|
Inventor(s):
Stephanie Jones
,
Nicholas Tolley
Keywords(s):
Category(s):
Neuroscience
1
2
3
4
5
6
7
8
9
10
...